scholarly journals MR Imaging Texture Analysis of the Corpus Callosum and Thalamus in Amnestic Mild Cognitive Impairment and Mild Alzheimer Disease

2010 ◽  
Vol 32 (1) ◽  
pp. 60-66 ◽  
Author(s):  
M.S. de Oliveira ◽  
M.L.F. Balthazar ◽  
A. D'Abreu ◽  
C.L. Yasuda ◽  
B.P. Damasceno ◽  
...  
Keyword(s):  
Cognitive Impairment ◽  
Mild Cognitive Impairment ◽  
Alzheimer Disease ◽  
Corpus Callosum ◽  
Mr Imaging ◽  
Texture Analysis ◽  
Amnestic Mild Cognitive Impairment

scholarly journals Amnestic Mild Cognitive Impairment: Structural MR Imaging Findings Predictive of Conversion to Alzheimer Disease

2008 ◽  
Vol 29 (5) ◽  
pp. 944-949 ◽  
Author(s):  
G. Karas ◽  
J. Sluimer ◽  
R. Goekoop ◽  
W. van der Flier ◽  
S.A.R.B. Rombouts ◽  
...  
Keyword(s):  
Cognitive Impairment ◽  
Mild Cognitive Impairment ◽  
Alzheimer Disease ◽  
Mr Imaging ◽  
Amnestic Mild Cognitive Impairment ◽  
Imaging Findings

Plasma BDNF levels are correlated with aggressiveness in patients with amnestic mild cognitive impairment or Alzheimer disease

2013 ◽  
Vol 121 (4) ◽  
pp. 433-441 ◽  
Author(s):  
Tomoyuki Nagata ◽  
Nobuyuki Kobayashi ◽  
Shunichiro Shinagawa ◽  
Hisashi Yamada ◽  
Kazuhiro Kondo ◽  
...  
Keyword(s):  
Cognitive Impairment ◽  
Mild Cognitive Impairment ◽  
Alzheimer Disease ◽  
Amnestic Mild Cognitive Impairment

3D Texture Analysis of Corpus Caliosum Based on MR Images Inpatients with Alzheimer’s Disease and Mild Cognitive Impairment

2014 ◽  
Vol 533 ◽  
pp. 415-420 ◽  
Author(s):  
Wei Fang Liu ◽  
Xu Wang ◽  
Hong Xia
Keyword(s):  
Cognitive Impairment ◽  
Mild Cognitive Impairment ◽  
Corpus Callosum ◽  
Texture Analysis ◽  
Three Dimensional ◽  
Texture Features ◽  
Grey Level ◽  
Run Length ◽  
3D Texture ◽  
3D Texture Analysis

This study investigated three-dimensional (3D) texture as a possible diagnostic marker of Alzheimers disease (AD). Methods: T1-weighted MRI of 18 AD patients, 18 Mild Cognitive Impairment (MCI) patients and 18 normal controls (NC) were selected.3D Texture parameters of the corpus callosum,including contrast, inverse difference moment , entropy, short run emphasis, long run emphasis, grey level nonuniformity, run length nonuniformity and fraction were extracted from the gray level co-occurrence matrix and run length matrix. Finally statistic significance was tested among three groups, and the correlations between parameters and Mini-Mental State Examination (MMSE) scores were calculated. Results: The results showed that the 3D texture features had significant differences (p<0.05) among three groups except grey level nonuniformity and run length nonuniformity that the difference was not significant (p>0.05) between MCI and NC or AD and MCI , and they were correlated with MMSE scores.Conclusions: 3D texture analysis can reflect the pathological changes of corpus callosum in patients with AD and MCI, and it may be helpful to AD early diagnosis.

scholarly journals Plasma amino acid concentrations in patients with amnestic mild cognitive impairment or Alzheimer disease

2004 ◽  
Vol 80 (2) ◽  
pp. 483-488 ◽  
Author(s):  
Giovanni Ravaglia ◽  
Paola Forti ◽  
Fabiola Maioli ◽  
Giampaolo Bianchi ◽  
Mabel Martelli ◽  
...  
Keyword(s):  
Cognitive Impairment ◽  
Mild Cognitive Impairment ◽  
Amino Acid ◽  
Alzheimer Disease ◽  
Amnestic Mild Cognitive Impairment ◽  
Plasma Amino Acid ◽  
Amino Acid Concentrations

scholarly journals Frontal White Matter Hyperintensity Is Associated with Verbal Aggressiveness in Elderly Women with Alzheimer Disease and Amnestic Mild Cognitive Impairment

2018 ◽  
Vol 8 (1) ◽  
pp. 138-150 ◽  
Author(s):  
Noriko Ogama ◽  
Takashi Sakurai ◽  
Naoki Saji ◽  
Toshiharu Nakai ◽  
Shumpei Niida ◽  
...  
Keyword(s):  
Cognitive Impairment ◽  
Mild Cognitive Impairment ◽  
White Matter ◽  
Alzheimer Disease ◽  
Frontal Lobe ◽  
Brain Atrophy ◽  
Amnestic Mild Cognitive Impairment ◽  
White Matter Hyperintensity ◽  
Verbal Aggressiveness ◽  
The Impact

Background/Aims: Behavioral and psychological symptoms of dementia (BPSD) are exhibited in most patients with Alzheimer disease (AD). Although white matter hyperintensity (WMH) is often observed with AD, the precise role of WMH in BPSD remains unclear. The current study aimed to identify the impact of regional WMH on specific features of BPSD in persons with mild to moderate AD and amnestic mild cognitive impairment (aMCI). Methods: A sample of 256 female outpatients with AD (n = 217) and aMCI (n = 39) were recruited. We assessed BPSD using the Dementia Behavior Disturbance Scale. WMH and brain atrophy were evaluated using an automatic segmentation program. Regional WMH was evaluated as periventricular hyperintensity (PVH) and deep WMH in frontal, temporal, occipital, and parietal lobes. Results: Whole-brain WMH was associated with verbal aggressiveness. In multivariate analysis, PVH in the frontal lobe was independently associated with verbal aggressiveness after adjustment for brain atrophy and clinical confounders. Conclusion: The current results indicated that PVH in the frontal lobe was independently associated with verbal aggressiveness.

scholarly journals Association Between Olfactory Dysfunction and Amnestic Mild Cognitive Impairment and Alzheimer Disease Dementia

2016 ◽  
Vol 73 (1) ◽  
pp. 93 ◽  
Author(s):  
Rosebud O. Roberts ◽  
Teresa J. H. Christianson ◽  
Walter K. Kremers ◽  
Michelle M. Mielke ◽  
Mary M. Machulda ◽  
...  
Keyword(s):  
Cognitive Impairment ◽  
Mild Cognitive Impairment ◽  
Alzheimer Disease ◽  
Amnestic Mild Cognitive Impairment ◽  
Olfactory Dysfunction

P1-169: MR imaging and clinical characteristics of dysexecutive and amnestic mild cognitive impairment

2008 ◽  
Vol 4 ◽  
pp. T257-T257
Author(s):  
Judy Pa ◽  
Adam L. Boxer ◽  
Linda L. Chao ◽  
Michael W. Weiner ◽  
Katie M. Freeman ◽  
...  
Keyword(s):  
Cognitive Impairment ◽  
Mild Cognitive Impairment ◽  
Mr Imaging ◽  
Clinical Characteristics ◽  
Amnestic Mild Cognitive Impairment
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