scholarly journals Underestimation of Cerebral Perfusion on Flow-Sensitive Alternating Inversion Recovery Image: Semiquantitative Evaluation with Time-to-Peak Values

2007 ◽  
Vol 28 (10) ◽  
pp. 2008-2013 ◽  
Author(s):  
H.S. Kim ◽  
S.Y. Kim ◽  
J.M. Kim
2004 ◽  
Vol 77 (918) ◽  
pp. 528-531 ◽  
Author(s):  
T Hirota ◽  
K Ishihara ◽  
K Akazawa ◽  
T Kubota ◽  
K Yamada ◽  
...  

1988 ◽  
Vol 27 (02) ◽  
pp. 51-56 ◽  
Author(s):  
H. Braun ◽  
A. Ferbert ◽  
H. Stirner ◽  
C. Weiller ◽  
E. B. Ringelstein ◽  
...  

In 53 patients with cerebrovascular disease (CVD), regional cerebral blood flow (CBF) and blood volume (CBV) were imaged by SPECT within one session. Slice division (CBF: CBV) yielded distribution of regional cerebral perfusion reserve (CPR). Semiquantitative evaluation was obtained from manually set ROIs by interhemispherical ratios (for CBF, CBV and CPR), using 2 SD from a normal group (n = 10) as a threshold. Sensitivities were 59% for CBF, 94% for CBV and 83% for CPR. Combined sensitivity was 98%. Establishing three constellations for CBF, CBV and CPR, regionally normal CBFs but quantitatively increased CBVs (+69%) and decreased CPRs (−31 %) were found in relatively early stages of CVD. Very advanced cases showed decreased CBFs (−65%), CBVs (−40%), CPRs (−49%) and a surrounding penumbra. In 87% (46/53 patients), such Theologically postulated constellations could be demonstrated. We conclude that combined CBF and CBV SPECT, assisted by CPR images, is a promising tool to detect CVD and to assess its individual regional severity.


Author(s):  
Christine U. Lee ◽  
James F. Glockner

62-year-old asymptomatic man with a heart murmur on physical examination; echocardiography revealed a cardiac mass, and MRI was requested for further characterization Sagittal oblique black-blood double (Figure 13.26.1) and triple (Figure 13.26.2) inversion recovery FSE images through the RVOT demonstrate a well-circumscribed ovoid mass with markedly increased signal intensity on the T2-weighted triple inversion recovery image. Axial proton density-weighted double inversion recovery images (...


2015 ◽  
Vol 123 (1) ◽  
pp. 59-64 ◽  
Author(s):  
Philipp Jörg Slotty ◽  
Marcel Alexander Kamp ◽  
Thomas Beez ◽  
Henrieke Beenen ◽  
Hans-Jakob Steiger ◽  
...  

OBJECT Multiple trials have shown improved survival and functional outcome in patients treated with decompressive craniectomy (DC) for brain swelling following major stroke. It has been assumed that decompression induces an improvement in cerebral perfusion. This observational study directly measured cerebral perfusion before and after decompression. METHODS Sixteen patients were prospectively examined with perfusion CT within 6 hours prior to surgery and 12 hours after surgery. Preoperative and postoperative perfusion measurements were compared and correlated. RESULTS Following DC there was a significant increase in cerebral blood flow in all measured territories and additionally an increase in cerebral blood volume in the penumbra (p = 0.03). These changes spread as far as the contralateral hemisphere. No significant changes in mean transit time or Tmax (time-to-peak residue function) were observed. CONCLUSIONS The presurgical perfusion abnormalities likely reflected local pressure-induced hypoperfusion with impaired autoregulation. The improvement in perfusion after decompression implied an increase in perfusion pressure, likely linked to partial restoration of autoregulation. The increase in perfusion that was observed might partially be responsible for improved clinical outcome following decompressive surgery for major stroke. The predictive value of perfusion CT on outcome needs to be evaluated in larger trials.


Stroke ◽  
2014 ◽  
Vol 45 (2) ◽  
pp. 450-455 ◽  
Author(s):  
Bum Joon Kim ◽  
Hye-Jin Kim ◽  
Deok Hee Lee ◽  
Sun U. Kwon ◽  
Sang Joon Kim ◽  
...  

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