Application of computer-assisted design in craniofacial reconstructive surgery using a commercial image guidance system

2006 ◽  
Vol 104 (1) ◽  
pp. 64-67 ◽  
Author(s):  
Joseph H. Piatt ◽  
Binil Starly ◽  
Wei Sun ◽  
Eric Faerber
Keyword(s):  
Reconstructive Surgery ◽  
Image Guidance ◽  
Guidance System ◽  
Computer Assisted ◽  
Computer Assisted Design

Revision cervical spine surgery using transarticular or pedicle screws under a computer-assisted image-guidance system

2005 ◽  
Vol 10 (4) ◽  
pp. 385-390 ◽  
Author(s):  
Atsushi Seichi ◽  
Katsushi Takeshita ◽  
Susumu Nakajima ◽  
Toru Akune ◽  
Hiroshi Kawaguchi ◽  
...  
Keyword(s):  
Cervical Spine ◽  
Spine Surgery ◽  
Image Guidance ◽  
Pedicle Screws ◽  
Guidance System ◽  
Computer Assisted ◽  
Cervical Spine Surgery ◽  
Computer Assisted Image

Computational Approaches for the Design of Mosquito Repellent Chemicals

2020 ◽  
Vol 27 (1) ◽  
pp. 32-41 ◽  
Author(s):  
Subhash C. Basak ◽  
Apurba K. Bhattacharjee
Keyword(s):  
Computational Design ◽  
Quantitative Structure Activity Relationship ◽  
Computer Assisted ◽  
Quantitative Structure ◽  
Mosquito Repellent ◽  
Computational Approaches ◽  
Qsar Studies ◽  
Computer Assisted Design ◽  
Structure Activity ◽  
Mosquito Repellents

Background: In view of many current mosquito-borne diseases there is a need for the design of novel repellents. Objective: The objective of this article is to review the results of the researches carried out by the authors in the computer-assisted design of novel mosquito repellents. Methods: Two methods in the computational design of repellents have been discussed: a) Quantitative Structure Activity Relationship (QSAR) studies from a set of repellents structurally related to DEET using computed mathematical descriptors, and b) Pharmacophore based modeling for design and discovery of novel repellent compounds including virtual screening of compound databases and synthesis of novel analogues. Results: Effective QSARs could be developed using mathematical structural descriptors. The pharmacophore based method is an effective tool for the discovery of new repellent molecules. Conclusion: Results reviewed in this article show that both QSAR and pharmacophore based methods can be used to design novel repellent molecules.

Is computer-assisted design and manufacturing technology useful in the surgical management of trigonocephaly?

2021 ◽  
Author(s):  
C.H.A.U.V.E.L.-P.I.C.A.R.D. Julie ◽  
B.E.U.R.I.A.T. Pierre-Aurélien ◽  
D.A.U.R.A.D.E. Mathieu ◽  
S.Z.A.T.H.M.A.R.I. Alexandru ◽  
M.O.T.T.O.L.E.S.E. Carmine ◽  
...  
Keyword(s):  
Surgical Management ◽  
Manufacturing Technology ◽  
Computer Assisted ◽  
Computer Assisted Design ◽  
Design And Manufacturing

Ablation of atrial tachyarrhythmias late after surgical repair of tetralogy of Fallot

2010 ◽  
Vol 21 (1) ◽  
pp. 31-38 ◽  
Author(s):  
Dan Raine ◽  
John O’Sullivan ◽  
Milind Chaudhari ◽  
Leslie Hamilton ◽  
Asif Hasan ◽  
...  
Keyword(s):  
Catheter Ablation ◽  
Tetralogy Of Fallot ◽  
Surgical Repair ◽  
Pulmonary Regurgitation ◽  
Clinical Problem ◽  
Guidance System ◽  
Computer Assisted ◽  
Atrial Tachyarrhythmias ◽  
Jude Medical ◽  
Repaired Tetralogy Of Fallot

AbstractBackgroundPatients with repaired tetralogy of Fallot may develop symptomatic and haemodynamic deterioration for many reasons such as arrhythmia, pulmonary regurgitation, and impairment in ventricular function. We describe a consecutive group of patients whose main clinical problem was atrial tachyarrhythmias.AimsTo describe the clinical outcome of atrial tachyarrhythmias occurring late after surgical repair of tetralogy of Fallot; to define the circuits/foci responsible for these atrial tachyarrhythmias; to evaluate the outcome of computer-assisted mapping and catheter ablation in this patient group.Methods and resultsConsecutive patients with surgically repaired tetralogy of Fallot and atrial tachyarrhythmias, who underwent catheter ablation between January, 2001 and June, 2007, were identified retrospectively from case records. Computer-assisted mapping was performed in all using either EnSite® (St Jude Medical Inc.) arrhythmia mapping and intra-cardiac catheter guidance system or CARTO™ (Biosense Webster Inc.) electroanatomical mapping systems. Ten patients (four males) with a median age of 39 plus or minus 8 years were studied. The total number of atrial tachyarrhythmias identified was 22 (six macro-reentrant, 16 micro-reentrant/focal). In nine patients, catheter ablation led to improvement in arrhythmia episodes and/or symptoms during follow-up of 41 plus or minus 20 months. Following ablation(s), five patients required pacing for pre-existing conduction disease and five needed further surgery for haemodynamic indications. All patients remained on anti-arrhythmic drugs.ConclusionsPatients with surgically repaired tetralogy of Fallot and atrial tachyarrhythmias typically have multiple arrhythmic circuits/foci arising from a scarred right atrium. Catheter ablation reduces arrhythmia frequency and improves symptoms. However, hybrid management is often required, comprising drugs, pacing, and further surgery tailored to the individual.

Computer-assisted design of novel 1,4-dihydropyridine calcium channel blockers

2013 ◽  
Vol 40 (12) ◽  
pp. 959-965 ◽  
Author(s):  
Estella G. da Mota ◽  
Daniel G. Silva ◽  
Maria C. Guimarães ◽  
Elaine F.F. da Cunha ◽  
Matheus P. Freitas
Keyword(s):  
Calcium Channel ◽  
Calcium Channel Blockers ◽  
Computer Assisted ◽  
Channel Blockers ◽  
Computer Assisted Design

Computer-assisted design for paracetamol masking bitter taste prodrugs

2011 ◽  
Vol 18 (1) ◽  
pp. 103-114 ◽  
Author(s):  
Hatem Hejaz ◽  
Rafik Karaman ◽  
Mustafa Khamis
Keyword(s):  
Bitter Taste ◽  
Computer Assisted ◽  
Computer Assisted Design

HIV vaccine development by computer assisted design: the GAIA vaccine

Vaccine ◽  
2005 ◽  
Vol 23 (17-18) ◽  
pp. 2136-2148 ◽  
Author(s):  
A DEGROOT ◽  
L MARCON ◽  
E BISHOP ◽  
D RIVERA ◽  
M KUTZLER ◽  
...  
Keyword(s):  
Vaccine Development ◽  
Hiv Vaccine ◽  
Computer Assisted ◽  
Computer Assisted Design
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