Neuroendoscopic management of interhemispheric cysts in children

2007 ◽  
Vol 22 (2) ◽  
pp. 194-202
Author(s):  
Giuseppe Cinalli ◽  
Paola Peretta ◽  
Pietro Spennato ◽  
Luciano Savarese ◽  
Antonio Varone ◽  
...  
Keyword(s):  
Corpus Callosum ◽  
Developmental Delay ◽  
The Other ◽  
Arachnoid Cysts ◽  
Attractive Alternative ◽  
Corpus Callosum Agenesis ◽  
Mild Developmental Delay ◽  
Brain Malformations ◽  
Endoscopic Methods

Object Interhemispheric arachnoid cysts are very rare, and they are often associated with complex brain malformations such as corpus callosum agenesis and hydrocephalus. Debate remains concerning the proper management of these lesions. Placement of shunts and microsurgical marsupialization of the cyst are the traditional options. Using endoscopic methods to create areas of communication between the cyst, the ventricular system, and/or the subarachnoid space is an attractive alternative to the use of shunts and microsurgery. Methods Between 2000 and 2005, seven consecutive pediatric patients with interhemispheric arachnoid cysts underwent neuroendoscopic treatment involving cystoventriculostomy in two patients, cystocisternostomy in two, and cystoventriculocisternostomy in three. There were three cases of associated hydrocephalus, six cases of corpus callosum agenesis, and one case of corpus callosum hypogenesis. The follow-up period ranged from 12 to 49 months (mean 31.6 months). Endoscopic procedures were completely successful in all but two patients. In one of the remaining two patients, a repeated endoscopic cystocisternostomy was performed with success because of closure of the previous stoma. In the other, a subcutaneous collection of cerebrospinal fluid (CSF) was managed by insertion of a lumboperitoneal shunt. A subdural collection of CSF developed in three patients; it was treated with insertion of a subduroperitoneal shunt in one patient and managed conservatively in the other two patients, resolving spontaneously without further treatment. Neurodevelopmental evaluation performed in six patients showed normal intelligence (total intelligence quotient [IQ] > 80) in three patients, mild developmental delay (total IQ 50–80) in two, and severe developmental delay (total IQ < 50) in one. Conclusions Endoscopic treatment of interhemispheric cysts can be considered a useful alternative to traditional treatments, even if some complications are to be expected, such as subdural or subcutaneous CSF collections and CSF leaks due to thinness of cerebral mantle and to the often-associated multifactorial hydrocephalus.

Percutaneous endoscopic treatment of suprasellar arachnoid cysts: ventriculocystostomy or ventriculocystocisternostomy?

1996 ◽  
Vol 84 (4) ◽  
pp. 696-701 ◽  
Author(s):  
Philippe Decq ◽  
Pierre Brugières ◽  
Caroline Le Guerinel ◽  
Michel Djindjian ◽  
Yves Kéravel ◽  
...  
Keyword(s):  
Magnetic Resonance ◽  
Flow Dynamics ◽  
The Other ◽  
Arachnoid Cysts ◽  
Csf Flow ◽  
Content Type ◽  
Secondary Closure ◽  
Fine Print

✓ The use of an endoscope in the treatment of suprasellar arachnoid cysts provides an opening of the upper and lower cyst walls, thereby allowing the surgeon to perform a ventriculocystostomy (VC) or a ventriculocystocysternostomy (VCC). To discover which procedure is appropriate, magnetic resonance (MR)—imaged cerebrospinal fluid (CSF) flow dynamics in two patients were analyzed, one having undergone a VC and the other a VCC using a rigid endoscope. Magnetic resonance imaging studies were performed before and after treatment, with long-term follow-up periods (18 months and 2 years). The two patients were reoperated on during the follow-up period because of slight headache recurrence in one case and MR—imaged CSF flow dynamics modifications in the other. In each case surgery confirmed the CSF flow dynamics modifications appearing on MR imaging. In both cases, long-term MR imaging follow-up studies showed a secondary closing of the upper wall orifice. After VCC, however, the lower communication between the cyst and the cisterns remained functional. The secondary closure of the upper orifice may be explained as follows: when opened, the upper wall becomes unnecessary and tends to return to a normal shape, leading to a secondary closure. The patent sylvian aqueduct aids this phenomenon, as observed after ventriculostomy when the aqueduct is secondarily functional. The simplicity of the VCC performed using endoscopic control, which is the only procedure to allow the opening in the cyst's lower wall to remain patent, leads the authors to advocate this technique in the treatment of suprasellar arachnoid cysts.

scholarly journals Long‐term follow‐up in a cohort of children with isolated corpus callosum agenesis at fetal MRI

2021 ◽  
Author(s):  
Romina Romaniello ◽  
Filippo Arrigoni ◽  
Patrizia De Salvo ◽  
Maria Clara Bonaglia ◽  
Elena Panzeri ◽  
...  
Keyword(s):  
Corpus Callosum ◽  
Fetal Mri ◽  
Corpus Callosum Agenesis ◽  
Long Term Follow Up

scholarly journals Surgical management of cerebellopontine angle arachnoid cysts associated with hearing deficit in pediatric patients

2018 ◽  
Vol 21 (2) ◽  
pp. 119-123
Author(s):  
Mario Giordano ◽  
Massimo Gallieni ◽  
Amir Samii ◽  
Concezio Di Rocco ◽  
Madjid Samii
Keyword(s):  
Hearing Loss ◽  
Surgical Treatment ◽  
Cerebellopontine Angle ◽  
Pediatric Patients ◽  
Clinical Symptoms ◽  
Complete Recovery ◽  
The Other ◽  
Arachnoid Cysts ◽  
Recent Onset

OBJECTIVEFew cases of cerebellopontine angle (CPA) arachnoid cysts in pediatric patients have been described in the literature, and in only 2 of these cases were the patients described as suffering from hearing deficit. In this article, the authors report on 3 pediatric patients with CPA arachnoid cysts (2 with hearing loss and 1 with recurrent headaches) who underwent neurosurgical treatment at the authors’ institution.METHODSFour pediatric patients were diagnosed with CPA arachnoid cysts at the International Neuroscience Institute during the period from October 2004 through August 2012, and 3 of these patients underwent surgical treatment. The authors describe the patients’ clinical symptoms, the surgical approach, and the results on long-term follow-up.RESULTSOne patient (age 14 years) who presented with headache (without hearing deficit) became asymptomatic after surgical treatment. The other 2 patients who underwent surgical treatment both had hearing loss. One of these children (age 9 years) had recent-onset hypacusia and experienced complete recovery immediately after the surgery. The other (age 6 years) had a longer history (2 years) of progressive hearing loss and showed an interruption of the deficit progression and only mild improvement at the follow-up visit.CONCLUSIONSCPA arachnoid cysts are uncommon in pediatric patients. The indication and timing of the surgical treatment are fundamental, especially when a hearing deficit is present.

Clinical Characterization, Genetics, and Long-Term Follow-up of a Large Cohort of Patients With Agenesis of the Corpus Callosum

2016 ◽  
Vol 32 (1) ◽  
pp. 60-71 ◽  
Author(s):  
Romina Romaniello ◽  
Susan Marelli ◽  
Roberto Giorda ◽  
Maria F. Bedeschi ◽  
Maria C. Bonaglia ◽  
...  
Keyword(s):  
Intellectual Disability ◽  
Corpus Callosum ◽  
Genetic Diagnosis ◽  
Language Disorders ◽  
Agenesis Of Corpus Callosum ◽  
Brain Malformations ◽  
Genetic Features ◽  
Long Term Follow Up

To gain a better understanding of the clinical and genetic features associated with agenesis of corpus callosum, we enrolled and characterized 162 patients with complete or partial agenesis of corpus callosum. Clinical and genetic protocols allowed us to categorize patients as syndromic subjects, affected by complex extra-brain malformations, and nonsyndromic subjects without any additional anomalies. We observed slight differences in sex ratio (56% males) and agenesis type (52% complete). Syndromic agenesis of corpus callosum subjects were prevalent (69%). We detected associated cerebral malformations in 48% of patients. Neuromotor impairment, cognitive and language disorders, and epilepsy were frequently present, regardless of the agenesis of corpus callosum subtype. Long-term follow-up allowed us to define additional indicators: syndromic agenesis of corpus callosum plus patients showed the most severe clinical features while isolated complete agenesis of corpus callosum patients had the mildest symptoms, although we observed intellectual disability (64%) and epilepsy (15%) in both categories. We achieved a definitive (clinical and/or genetic) diagnosis in 42% of subjects.

scholarly journals Agenesis of the corpus callosum is associated with developmental delay and intellectual disability

2019 ◽  
Vol 5 (2) ◽  
Author(s):  
Quinton J Mandle
Keyword(s):  
Intellectual Disability ◽  
Corpus Callosum ◽  
Developmental Delay ◽  
Clinical Application ◽  
Critical Appraisal ◽  
Large Cohort ◽  
Child Neurology ◽  
Long Term Follow Up

<p>A critical appraisal and clinical application of Romaniello R, Marelli S, Giorda R, et al. Clinical characterization, genetics, and long-term follow-up of a large cohort of patients with agenesis of the corpus callosum. <em>Journal of Child Neurology</em>, 2016;32(1):60-71. doi: <a href="https://doi.org/10.1177/0883073816664668">10.1177/0883073816664668</a>.</p>

scholarly journals Apert syndrome: Cranial procedures and brain malformations in a series of patients

2020 ◽  
Vol 11 ◽  
pp. 361
Author(s):  
Pablo M. Munarriz ◽  
Beatriz Pascual ◽  
Ana M. Castaño-Leon ◽  
Ignacio García-Recuero ◽  
Marta Redondo ◽  
...  
Keyword(s):  
Corpus Callosum ◽  
Chiari Malformation ◽  
Septum Pellucidum ◽  
Cranial Vault ◽  
Apert Syndrome ◽  
Published Data ◽  
Syndromic Craniosynostosis ◽  
Brain Malformations

Background: Apert syndrome is one of the most severe craniofacial disorders. This study aims to describe the craniofacial surgeries and central nervous system malformations of a cohort of children with Apert syndrome treated in the past 20 years and to compare these data with previously published data. Methods: Retrospective analysis of a series of patients with Apert syndrome treated between 1999 and 2019 in our hospital. Information was analyzed regarding craniofacial procedures, hydrocephalus and presence of shunts, Chiari malformation Type 1, and other brain malformations such as corpus callosum and septum pellucidum anomalies. Results: Thirty-seven patients were studied. Ventriculoperitoneal shunt prevalence was 24.3%, and 8.1% of patients required decompressive surgery for Chiari malformation. All of them needed at least one cranial vault remodeling procedure. The median age for this procedure was 8 months. In 69.7% of patients, the first cranial vault intervention was performed in the fronto-orbital region. In 36.4% of patients, a midface advancement had been performed at the time of this review, although this proportion was very dependent on the follow-up period and the age of the patients. The median age for the midface advancement procedure was 5.25 years. Anomalies of the corpus callosum and the septum pellucidum were reported in 43.2% and 59.5% of patients, respectively. Conclusion: Apert syndrome is a type of syndromic craniosynostosis, and patients usually require one or more cranial and facial surgeries. In comparison with other syndromic craniosynostosis types, Apert syndrome less frequently requires a VP shunt or treatment for a Chiari malformation.

scholarly journals Two cases of vici syndrome presenting with corpus callosum agenesis, albinism, and severe developmental delay

2020 ◽  
Vol 62 (3) ◽  
pp. 474
Author(s):  
Mina Hızal ◽  
Batuhan Yeke ◽  
Yılmaz Yıldız ◽  
, Ali Öztürk ◽  
Berrak Bilginer Gürbüz ◽  
...  
Keyword(s):  
Corpus Callosum ◽  
Developmental Delay ◽  
Corpus Callosum Agenesis

Isolated corpus callosum agenesis: a ten-year follow-up after prenatal diagnosis (How are the children without corpus callosum at 10 years of age?)

2012 ◽  
Vol 32 (3) ◽  
pp. 277-283 ◽  
Author(s):  
Marie-Laure Moutard ◽  
Virginie Kieffer ◽  
Josué Feingold ◽  
Fanny Lewin ◽  
Jean-Michel Baron ◽  
...  
Keyword(s):  
Prenatal Diagnosis ◽  
Corpus Callosum ◽  
Corpus Callosum Agenesis
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