Pediatric spinal clear cell meningioma

2009 ◽  
Vol 3 (1) ◽  
pp. 57-60 ◽  
Author(s):  
Chaim B. Colen ◽  
Mahmoud Rayes ◽  
Jamal McClendon ◽  
Raja Rabah ◽  
Steven D. Ham

In this report the authors describe a unique case of spinal clear cell meningioma in a 13-year-old girl. Clear cell meningiomas (CCMs) are not uncommon. To the authors' knowledge, 14 cases of pediatric CCM occurring in the spinal canal have been reported. Factors lending resistance to meningioma initiation and invasion are analyzed. This 13-year-old girl presented with pain radiating down her left leg. Admission MR imaging showed an inhomogeneous enhancing intradural-extramedullary mass at the L4–5 level. Resection revealed a CCM, and radiotherapy was subsequently administered. Postoperatively there has been no recurrence in > 2 years. In this paper the authors report a case of CCM and provide a comprehensive literature review on this disease. Current recommendations for its management are still debatable, especially in the pediatric population, and the authors propose an algorithm for its treatment and surveillance.

2002 ◽  
Vol 3 (2) ◽  
pp. 125 ◽  
Author(s):  
Ki Bong Yu ◽  
Myung Kwan Lim ◽  
Hyung Jin Kim ◽  
Chang Hae Suh ◽  
Hyung Chun Park ◽  
...  

2012 ◽  
Vol 28 (12) ◽  
pp. 2143-2151 ◽  
Author(s):  
Zhiqi Li ◽  
Yi Zhang ◽  
Enming Wang ◽  
Zhiqiu Wang ◽  
Wengang Li ◽  
...  

2003 ◽  
Vol 10 (2) ◽  
pp. 264-266 ◽  
Author(s):  
Kayhan KuzeylıÇ ◽  
Ertuğrul Çakir ◽  
Haydar Usul ◽  
Gökalp Karaarslan ◽  
A Kadir Reıs ◽  
...  

2016 ◽  
Vol 33 (2) ◽  
pp. 239-248 ◽  
Author(s):  
Hao Li ◽  
Meng Zhao ◽  
Yuming Jiao ◽  
Zhicen Li ◽  
Ji Ma ◽  
...  

2015 ◽  
Vol 16 (3) ◽  
pp. 296-300 ◽  
Author(s):  
Linton T. Evans ◽  
Jack Van Hoff ◽  
William F. Hickey ◽  
Miriam J. Smith ◽  
D. Gareth Evans ◽  
...  

Clear cell meningioma (CCM) is an uncommon variant of meningioma. The authors describe a case of a pediatric CCM localized to the lumbar spine. After resection, sequencing revealed an inactivating mutation in the SWI/SNF chromatin remodeling complex subunit SMARCE1, with loss of the second allele in the tumor. The authors present a literature review of this mutation that is associated with CCM and a family history of spine tumors.


2010 ◽  
Vol 46 (6) ◽  
pp. 462-465 ◽  
Author(s):  
O.T. Burgan ◽  
A. Bahl ◽  
V. Critcher ◽  
H.S. Zaki ◽  
P.J. McMullan ◽  
...  

2000 ◽  
Vol 29 (4) ◽  
pp. 187-195 ◽  
Author(s):  
L. H. De Beuckeleer ◽  
A. M. De Schepper ◽  
J. E. Vandevenne ◽  
J. L. Bloem ◽  
A. M. Davies ◽  
...  

2021 ◽  
pp. 1-11
Author(s):  
Kelly E. Flanagan ◽  
Laura J. Burns ◽  
James T. Pathoulas ◽  
Chloe J. Walker ◽  
Isabel Pupo Wiss ◽  
...  

Alopecia neoplastica (AN) is caused by neoplastic cells damaging hair follicles, resulting in patchy hair loss like cicatricial alopecia and alopecia areata. AN has predominantly described cutaneous metastasis to the scalp from primary visceral malignant tumors. Less frequently, AN results from a primary scalp neoplasm. Compared to “secondary AN,” there is a paucity of literature on “primary AN.” Herein, we present a comprehensive literature review of primary AN and introduce a unique case of amelanotic melanoma causing primary AN. Including our presented case, 11 cases of primary AN have been reported with causative scalp neoplasms including angiosarcoma, hemangioendothelioma, syringomatous carcinoma, ectopic extramammary Paget’s disease, and primary desmoplastic melanoma. 27.3% (3 of 11) of cases were misdiagnosed and treated for a primary alopecia, and 36.4% (4 of 11) of lesions were present for multiple years or an unknown amount of time, likely due to difficulty in recognizing scalp lesion or misdiagnosis. All patients required surgical excision with 36.4% (4 of 11) requiring chemotherapy, radiation, or photodynamic therapy. Two patients with scalp angiosarcoma died from their aggressive disease. Due to the risks of malignant primary AN if allowed to progress, primary AN should be considered in patients presenting with scarring alopecia.


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