scholarly journals Assessment of Bone Mineral Density before and after Exercise Training in Postmenopausal Women.

1998 ◽  
Vol 24 (1) ◽  
pp. 53-57
Author(s):  
Salwa M. EL-BADRY ◽  
Hanan H. FOUAD
2014 ◽  
Vol 7 ◽  
pp. CMED.S15086 ◽  
Author(s):  
Helisane Lima ◽  
Juliana Maia ◽  
Francisco Bandeira

Objective To evaluate the responses of C-terminal telopeptide (CTX) and serum osteocalcin after the first 4 months of treatment with strontium ranelate (SR) and demonstrate their association with long-term bone density changes. Subjects and Methods A sample of 13 postmenopausal women with osteoporosis was analyzed (mean age 65 ± 7.7 years), who were treated with SR for an average of 2.56 ± 0.86 years. All patients had undergone previous treatment with bisphosphonates for an average period of 4.88 ± 2.27 years. Serum CTX and osteocalcin levels were determined before and after four months of treatment with SR. Bone mineral density in the lumbar spine and femoral neck were obtained before and after treatment with SR. Results We observed an average increase of 53.7% in the CTX levels, and 30.7% in the osteocalcin levels. The increase in bone markers was associated with a mean 4.8% increase in lumbar spine bone mineral density (BMD) from 0.820 to 0.860 g/cm2 ( T-score from –2.67 to –1.92; P= 0.001), after 2.5 years of treatment with SR. Conclusion These data suggest an anabolic effect of SR on postmenopausal women who were previously treated with long-term bisphosphonates.


2010 ◽  
Vol 44 (Suppl_1) ◽  
pp. i63-i63
Author(s):  
R. Nuri ◽  
A. Damirchi ◽  
F. Rahmani-Nia ◽  
N. Rahnama ◽  
H. Emami

2020 ◽  
Vol 106 (6) ◽  
pp. 577-590 ◽  
Author(s):  
Gholam Rasul Mohammad Rahimi ◽  
Neil A. Smart ◽  
Michael T. C. Liang ◽  
Nahid Bijeh ◽  
Alsaeedi L. Albanaqi ◽  
...  

2008 ◽  
Vol 33 (1) ◽  
pp. 200-212 ◽  
Author(s):  
Philip D. Chilibeck ◽  
Stephen M. Cornish

Exercise has a beneficial effect on bone, possibly by stimulating estrogen receptor α. Because estrogen up-regulates this receptor, estrogen therapy combined with exercise training may be optimal for increasing bone mineral density. Studies combining estrogen therapy and exercise training in postmenopausal women show mixed results, but indicate that the combination of interventions may be more effective for increasing bone mass than either intervention alone. Plant-like estrogens (i.e phytoestrogens such as soy isoflavones) may act as weak estrogen agonists or antagonists, have small beneficial effects on bone, and may interact with exercise for increasing bone mineral density. Phytoestrogen derived from flaxseed (flax lignans) has not been evaluated as extensively as soy isoflavones and thus its effect on bone is difficult to determine. Estrogen or soy isoflavones given to postmenopausal women results in a small increase in lean tissue mass that may be mediated through estrogen receptor α on muscle or through decreased inflammation.


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