scholarly journals Primary Fallopian Tube Carcinoma, A Rare Disease: Case Report and Mini Review of The Literature

2020 ◽  
pp. 1-4
Author(s):  
Pinelopi Gkogkou ◽  
Chasiotis Athanasios ◽  
Ioannis Thanasas ◽  
Pinelopi Gkogkou
Keyword(s):  
Histological Examination ◽  
Fallopian Tube ◽  
Lateral Wall ◽  
Current Data ◽  
Fallopian Tube Carcinoma ◽  
Surgical Specimen ◽  
Primary Fallopian Tube Carcinoma ◽  
Disease Case ◽  
One Year ◽  
The Right

The description of the case relates to a 48-year-old premenopausal patient, who was referred to the gynecologic outpatient clinic with ongoing and persistent vaginal bleeding, after undergoing a diagnostic endometrial curettage due to menorrhagias, whose histological examination revealed no pathologic findings. Ultrasound examination confirmed the presence of known multiple fibroids, with the largest lesion being estimated to occupy the right lateral wall of the uterus and extending towards the adnexa. The patient's surgical treatment was decided. During the operation, the presence of a solid mass that occupied the entire right fallopian tube, without the involvement of the ovary, was detected. Abdominal total hysterectomy and bilateral salpingo-oophorectomy were performed. The histological examination of the surgical specimen confirmed the diagnosis of fallopian tube carcinoma. The post-operative course of the patient was uncomplicated and adjuvant chemotherapy was initiated at an oncology center. One year later the general condition of the patient is normal, while she is regularly followed up by an oncologic medical team. In the present study, a brief overview of this rare entity is attempted on the basis of current data, concerning mainly the diagnostic and therapeutic approach, the appropriate application of which can contribute the best possible prognostic result.

scholarly journals Primary Fallopian Tube Carcinoma: A Case Report and Literature Review

2017 ◽  
Vol 5 (3) ◽  
pp. 344-348 ◽  
Author(s):  
Meral Rexhepi ◽  
Elizabeta Trajkovska ◽  
Hysni Ismaili ◽  
Florin Besimi ◽  
Nagip Rufati
Keyword(s):  
Fallopian Tube ◽  
Female Genital Tract ◽  
Lower Abdominal Pain ◽  
Ca 125 ◽  
Histopathological Diagnosis ◽  
Fallopian Tube Carcinoma ◽  
Rare Tumour ◽  
Initial Surgery ◽  
Primary Fallopian Tube Carcinoma ◽  
The Right

BACKGROUND: Primary fallopian tube carcinoma (PFTC) is a rare tumour of the female genital tract with an incidence of 0.1-1.8% of all genital malignancies, and it is very difficult to diagnose preoperatively, because of its non-specific symptomatology. In most cases, it is an intraoperative finding or a histopathological diagnosis. It is a tumour that histologically and clinically resembles epithelial ovarian cancer.CASE PRESENTATION: We are reporting a case of a 62-year-old, postmenopausal women with primary fallopian tube carcinoma of the right fallopian tube in stage IA. The patient has lower abdominal pain, watery vaginal discharge and repeated episodes of bleeding from the vagina. The clinical and radiological findings suggested a right adnexal tumour with elevated CA-125 levels. Total abdominal hysterectomy, bilateral salpingo-oophorectomy, omentectomy and peritoneal washing were performed. Pathologic confirmation of primary serous cystadenocarcinoma of the right fallopian tube was made. Peritoneal washings were negative for malignancy. FIGO stage was considered as IA, and the patient received no courses of chemotherapy and postoperative radiation because she refused it. Ten months after initial surgery, the patient is alive and in good condition.CONCLUSION: Cytoreduction surgery followed by adequate cycles of chemotherapy is an important strategy to improve patients’ prognosis.

scholarly journals Primary Fallopian Tube Carcinoma Discovered as an Incidental Finding - A Case Report

2018 ◽  
Vol 17 (2) ◽  
pp. 64-67
Author(s):  
Mrinalini Singh ◽  
Sanjay Das ◽  
Shilpi Shaukin
Keyword(s):  
Fallopian Tube ◽  
Incidental Finding ◽  
Malignant Tumour ◽  
Ovarian Neoplasm ◽  
Clinical Feature ◽  
Fallopian Tube Carcinoma ◽  
Primary Fallopian Tube Carcinoma ◽  
Specific Clinical Feature ◽  
One Year ◽  
Gynaecological Tumours

Introduction: Primary malignant tumour of fallopian tube is very rare. The reported incidence of tumour varies from 0.1 to 1.8% of all gynaecological cancers. There is no specific clinical feature and therefore the disease is often misdiagnosed as ovarian neoplasm or other gynaecological tumours. A preoperative diagnosis even by radiological assay is many times difficult because the features are similar to ovarian neoplasm, tubo-ovarian abscess or hydrosalpinx. We report a case of 45 years old female who presented with multiple episodes of pervaginum bleeding since past one year and was diagnosed as primary fallopian tube carcinoma on histopathology examination.

Preoperative Sonographic Diagnosis of Primary Fallopian Tube Carcinoma

2002 ◽  
Vol 21 (10) ◽  
pp. 1171-1173 ◽  
Author(s):  
Jimmy H. F. Yuen ◽  
Grace C. Y. Wong ◽  
Christina H. L. Lam
Keyword(s):  
Fallopian Tube ◽  
Fallopian Tube Carcinoma ◽  
Sonographic Diagnosis ◽  
Primary Fallopian Tube Carcinoma

scholarly journals Primary Fallopian Tube Carcinoma Arising in the Setting of Chronic Pelvic Inflammatory Disease

2014 ◽  
Vol 2014 ◽  
pp. 1-7 ◽  
Author(s):  
Ibrahim M. Zardawi
Keyword(s):  
Ovarian Cancer ◽  
Pelvic Inflammatory Disease ◽  
Chronic Inflammation ◽  
Fallopian Tube ◽  
Inflammatory Disease ◽  
Fallopian Tube Carcinoma ◽  
Fallopian Tube Cancer ◽  
Primary Fallopian Tube Carcinoma ◽  
Gynaecological Malignancy

Primary fallopian tube cancer (PFTC) is a rare gynaecological malignancy, clinically often mistaken for pelvic inflammatory disease or ovarian cancer. Three primary fallopian tube carcinomas, arising in a background of chronic pelvic inflammatory disease (PID), are presented. The possible association between chronic PID and PFTC is discussed and a hypothesies linking these cancers with chronic inflammation is proposed.

scholarly journals The role of cytology in preoperative assessment od primary fallopian tube carcinoma: case report

2016 ◽  
Vol 52 (3) ◽  
pp. 415-420
Author(s):  
Roberta Rubeša-Mihaljević ◽  
Damjana Verša Ostojić ◽  
Morana D inter ◽  
Snježana Štemberger-Papić ◽  
Senija Eminović ◽  
...  
Keyword(s):  
Case Report ◽  
Fallopian Tube ◽  
Preoperative Assessment ◽  
Fallopian Tube Carcinoma ◽  
Primary Fallopian Tube Carcinoma

scholarly journals Fallopian Tube Carcinoma

2019 ◽  
Vol 15 (7) ◽  
pp. 375-382 ◽  
Author(s):  
Marina Stasenko ◽  
Olga Fillipova ◽  
William P. Tew
Keyword(s):  
Fallopian Tube ◽  
Patient Survival ◽  
Gene Mutations ◽  
Adenosine Diphosphate ◽  
Parp Inhibitors ◽  
Fallopian Tube Carcinoma ◽  
Ovarian Cancers ◽  
Primary Fallopian Tube Carcinoma ◽  
Platinum Based Chemotherapy ◽  
Dose Dense

Primary fallopian tube carcinoma is a rare and difficult to cure disease. It is often grouped under the epithelial ovarian cancer umbrella, together with primary ovarian and peritoneal carcinomas. More recent evidence has suggested that epithelial ovarian cancers originate from a fallopian tube precursor. The mainstay of treatment is surgical cytoreduction and platinum-based chemotherapy. There is much debate over the best timing for surgery and the best approach to delivering the chemotherapy: traditional intravenous once every 3 weeks regimen, versus intraperitoneal, versus dose-dense intravenous regimens. Although these debates continue, novel targeted therapies, including bevacizumab and poly(adenosine diphosphate [ADP]-ribose) polymerase (PARP) inhibitors, have emerged. PARP inhibitors are particularly efficacious in patients with BRCA1/2 gene mutations, and their use has been shown to prolong patient survival. This article reviews the pathologic etiology; describes the heredity, treatment challenges, and controversies; and summarizes novel therapies in primary fallopian tube carcinoma.

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