scholarly journals Bacterial Cold-water Disease in Salmonid Fish and Ayu

2016 ◽  
Vol 51 (4) ◽  
pp. 153-157 ◽  
Author(s):  
Akira Kumagai
Keyword(s):  
Cold Water ◽  
Salmonid Fish ◽  
Bacterial Cold Water Disease

scholarly journals Viable but Non-culturable State of Bacterial Cold-water Disease Pathogen Flavobacterium psychrophilum at Various Temperatures

2010 ◽  
Vol 45 (4) ◽  
pp. 158-163 ◽  
Author(s):  
Kazuhiro Sugahara ◽  
Erina Fujiwara-Nagata ◽  
Ayami Fukuda ◽  
Mitsuru Eguchi
Keyword(s):  
Cold Water ◽  
Flavobacterium Psychrophilum ◽  
Bacterial Cold Water Disease

scholarly journals Detection and Validation of QTL Affecting Bacterial Cold Water Disease Resistance in Rainbow Trout Using Restriction-Site Associated DNA Sequencing

PLoS ONE ◽  
2015 ◽  
Vol 10 (9) ◽  
pp. e0138435 ◽  
Author(s):  
Yniv Palti ◽  
Roger L. Vallejo ◽  
Guangtu Gao ◽  
Sixin Liu ◽  
Alvaro G. Hernandez ◽  
...  
Keyword(s):  
Disease Resistance ◽  
Rainbow Trout ◽  
Dna Sequencing ◽  
Restriction Site ◽  
Cold Water ◽  
Bacterial Cold Water Disease

scholarly journals Neutrophil Migration in the Activation of the Innate Immune Response to DifferentFlavobacterium psychrophilumVaccines in Zebrafish (Danio rerio)

2015 ◽  
Vol 2015 ◽  
pp. 1-9 ◽  
Author(s):  
Camila J. Solís ◽  
Matías Poblete-Morales ◽  
Sergio Cabral ◽  
Juan A. Valdés ◽  
Ariel E. Reyes ◽  
...  
Keyword(s):  
Immune System ◽  
Danio Rerio ◽  
Innate Immune System ◽  
Cold Water ◽  
Neutrophil Migration ◽  
Innate Immune ◽  
Commercial Vaccine ◽  
Bacterial Cold Water Disease ◽  
Effectiveness And Efficiency ◽  
Rainbow Trout Fry Syndrome

Flavobacterium psychrophilumis a Gram-negative bacterium, responsible for the bacterial cold-water disease and the rainbow trout fry syndrome in freshwater salmonid fish. At present, there is only one commercial vaccine in Chile, made with two ChileanF. psychrophilumisolates and another licensed in Europe. The present study analyzed neutrophil migration, as a marker of innate immune activation, in zebrafish (Danio rerio) in response to differentF. psychrophilumbath vaccines, which is the first step in evaluating vaccine effectiveness and efficiency in fish. Results indicated that bacterins of the LM-02-Fp isolate were more immunogenic than those from the LM-13-Fp isolate. However, no differences were observed between the same bacteria inactivated by either formaldehyde or heat. Importantly, the same vaccine formulation without an adjuvant only triggered a mild neutrophil migration compared to the complete vaccine. Observations also found that, after a year of storage at 4°C, the activation of the innate immune system by the different vaccines was considerably decreased. Finally, new vaccine formulations prepared with heat and formaldehyde inactivated LM-02-Fp were significantly more efficient than the available commercial vaccine in regard to stimulating the innate immune system.

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