Empiric antibiotics for general infection

2013 ◽  
Author(s):  
Team DFTB
Keyword(s):  
Empiric Antibiotics

Analysis of Life-Threatening Complications of Deep Neck Abscess and the Impact of Empiric Antibiotics

ORL ◽  
2008 ◽  
Vol 70 (4) ◽  
pp. 249-256 ◽  
Author(s):  
Shih-Wei Yang ◽  
Ming-Hsun Lee ◽  
Yun-Shien Lee ◽  
Shu-Huan Huang ◽  
Tai-An Chen ◽  
...  
Keyword(s):  
Neck Abscess ◽  
Empiric Antibiotics ◽  
Life Threatening ◽  
Deep Neck Abscess ◽  
The Impact

scholarly journals Prescribing Empiric Antibiotics for Febrile Neutropenia: Compliance with Institutional Febrile Neutropenia Guidelines

Pharmacy ◽  
2018 ◽  
Vol 6 (3) ◽  
pp. 83 ◽  
Author(s):  
Doaa Naeem ◽  
Majed Alshamrani ◽  
Mohammed Aseeri ◽  
Mansoor Khan
Keyword(s):  
Febrile Neutropenia ◽  
Cancer Patients ◽  
Bacterial Infections ◽  
Cross Sectional Study ◽  
Cross Sectional ◽  
Management Guidelines ◽  
Empiric Antibiotics ◽  
Inappropriate Use ◽  
Common Diagnosis ◽  
The Mean

Background: Febrile neutropenia (FN) is an oncologic emergency which should be treated immediately with empiric antibiotics. Different institutions observe different antibiograms and use different FN management guidelines. Our center implemented FN management guidelines for adult cancer patients in 2009. Hence, we decided to assess compliance with FN management guidelines and to describe the pattern of bacterial infections. Method: We conducted a cross-sectional study on all adult cancer patients admitted with FN. Data were collected from electronic medical records between January and December 2014. Results: One hundred FN episodes met the study inclusion criteria. The mean age of the patients was 41 ± 17 years; 52% (52 patients) were women. The most common diagnosis was lymphoma (33%). In terms of compliance to institutional FN guidelines, 55% of patients received guideline non-compliant treatment. The most common non-compliant treatment was incorrect amikacin dosing in 31% of patients, followed by incorrect vancomycin dosing in 20%, incorrect piperacillin/tazobactam dosing in 19%, inappropriate use of carbapenems in 18%, and non-compliant vancomycin use in 12% of patients. Bacterial isolates were only observed in 19% of the FN episodes. Among these 19 episodes of FN, Gram-negative pathogens were predominant and were identified in 74% of the episodes, followed by Gram-positive pathogens in 16% and polymicrobial pathogens in 10%. The mean time to defervescence was 2.21 ± 2 days. Conclusion: Our study concluded that there was a high percentage of non-compliance with our institutional FN management guidelines. We recommend following appropriate empiric antibiotic doses and indications as per institutional guidelines.

scholarly journals Pathogen-Negative Sepsis—An Opportunity for Antimicrobial Stewardship

2019 ◽  
Vol 6 (10) ◽  
Author(s):  
Gabriel C Lockhart ◽  
Jacob Hanin ◽  
Scott T Micek ◽  
Marin H Kollef
Keyword(s):  
Median Duration ◽  
Antimicrobial Stewardship ◽  
Hospitalized Patients ◽  
Interquartile Range ◽  
Common Reason ◽  
Empiric Antibiotics

Abstract Sepsis is a common reason for empiric antibiotics among hospitalized patients. We found that the median duration of empiric antibiotics (interquartile range) was 6 (4–9) days among 1047 survivivors with pathogen-negative sepsis. These findings suggest that patients with pathogen-negative sepsis could represent an important opportunity for antimicrobial stewardship.

Diagnostic Yield of Initial and Consecutive Blood Cultures in Children With Cancer and Febrile Neutropenia

2020 ◽  
Author(s):  
Gabrielle M Haeusler ◽  
Richard De Abreu Lourenco ◽  
Hannah Clark ◽  
Karin A Thursky ◽  
Monica A Slavin ◽  
...  
Keyword(s):  
Febrile Neutropenia ◽  
Bloodstream Infection ◽  
Healthcare Workers ◽  
Diagnostic Yield ◽  
Infectious Complications ◽  
Blood Cultures ◽  
Children With Cancer ◽  
Persistent Fever ◽  
Empiric Antibiotics ◽  
Clinical Instability

Abstract Background The timing and necessity of repeated blood cultures (BCs) in children with cancer and febrile neutropenia (FN) are unknown. We evaluated the diagnostic yield of BCs collected pre- and post-empiric FN antibiotics. Methods Data collected prospectively from the Australian Predicting Infectious ComplicatioNs in Children with Cancer (PICNICC) study were used. Diagnostic yield was calculated as the number of FN episodes with a true bloodstream infection (BSI) detected divided by the number of FN episodes that had a BC taken. Results A BSI was identified in 13% of 858 FN episodes. The diagnostic yield of pre-antibiotic BCs was higher than of post-antibiotic cultures (12.3% vs 4.4%, P < .001). Two-thirds of the post-antibiotic BSIs were associated with a new episode of fever or clinical instability, and only 2 new BSIs were identified after 48 hours of empiric antibiotics and persistent fever. A contaminated BC was identified more frequently in post-antibiotic cultures. Conclusions In the absence of new fever or clinical instability, BCs beyond 48 hours of persistent fever have limited yield. Opportunity exists to optimize BC collection in this population and reduce the burden of unnecessary tests on patients, healthcare workers, and hospitals.

Diagnostic yield and clinical impact of microbiologic diagnosis from CT-guided drainage in patients previously treated with empiric antibiotics

2016 ◽  
Vol 42 (1) ◽  
pp. 298-305
Author(s):  
Kathryn L. McGillen ◽  
Johannes Boos ◽  
Ruvandhi Nathavitharana ◽  
Alexander Brook ◽  
Maryellen R. Sun ◽  
...  
Keyword(s):  
Diagnostic Yield ◽  
Clinical Impact ◽  
Ct Guided ◽  
Empiric Antibiotics ◽  
Previously Treated ◽  
Microbiologic Diagnosis

Empiric Antibiotics for Acute Infections of the Hand

2010 ◽  
Vol 35 (1) ◽  
pp. 125-128 ◽  
Author(s):  
Rick Tosti ◽  
Asif M. Ilyas
Keyword(s):  
Empiric Antibiotics ◽  
Acute Infections

Empiric Antibiotics for Serious Bacterial Infection in Young Infants

2015 ◽  
Vol 31 (8) ◽  
pp. 568-571 ◽  
Author(s):  
Joseph B. Cantey ◽  
Eduardo Lopez-Medina ◽  
Sean Nguyen ◽  
Christopher Doern ◽  
Carla Garcia
Keyword(s):  
Bacterial Infection ◽  
Empiric Antibiotics ◽  
Young Infants
Sign in / Sign up

Export Citation Format

Share Document