scholarly journals Cognitive Processes in Parkinson's Disease. An Event-related Potential Analysis.

1991 ◽  
Vol 28 (6) ◽  
pp. 801-810 ◽  
Author(s):  
Kazuo Toda
Keyword(s):  
Parkinson’S Disease ◽  
Parkinson's Disease ◽  
Cognitive Processes ◽  
Event Related Potential ◽  
Potential Analysis

scholarly journals Current source density approaches improve spatial resolution in event related potential analysis in people with Parkinson’s disease

2019 ◽  
Vol 130 (10) ◽  
pp. 1998-1999 ◽  
Author(s):  
Conor Fearon ◽  
John S. Butler ◽  
Saskia M. Waechter ◽  
Isabelle Killane ◽  
Richard B. Reilly ◽  
...  
Keyword(s):  
Parkinson’S Disease ◽  
Parkinson's Disease ◽  
Spatial Resolution ◽  
Current Source ◽  
Event Related Potential ◽  
Current Source Density ◽  
Potential Analysis ◽  
Source Density

Event-related potential P3 change in mild Parkinson's disease

1996 ◽  
Vol 11 (1) ◽  
pp. 32-42 ◽  
Author(s):  
Joanne Green ◽  
John L. Woodard ◽  
Brett E. Sirockman ◽  
Gregory O. Zakers ◽  
Claire L. Maier ◽  
...  
Keyword(s):  
Parkinson’S Disease ◽  
Parkinson's Disease ◽  
Event Related Potential

scholarly journals Lexical ambiguity resolution during sentence processing in Parkinson’s disease: An event-related potential study

PLoS ONE ◽  
2017 ◽  
Vol 12 (5) ◽  
pp. e0176281 ◽  
Author(s):  
Anthony J. Angwin ◽  
Nadeeka N. W. Dissanayaka ◽  
Katie L. McMahon ◽  
Peter A. Silburn ◽  
David A. Copland
Keyword(s):  
Parkinson’S Disease ◽  
Parkinson's Disease ◽  
Sentence Processing ◽  
Ambiguity Resolution ◽  
Lexical Ambiguity ◽  
Event Related Potential ◽  
Lexical Ambiguity Resolution ◽  
Potential Study

scholarly journals Objective Assessment of Impulse Control Disorder in Patients with Parkinson’s Disease Using a Low-Cost LEGO-Like EEG Headset

2020 ◽  
Author(s):  
Yuan-Pin Lin ◽  
Hsing-Yi Liang ◽  
Yueh-Sheng Chen ◽  
Cheng-Hsien Lu ◽  
Yih-Ru Wu ◽  
...  
Keyword(s):  
Parkinson’S Disease ◽  
Adverse Effect ◽  
Parkinson's Disease ◽  
Impulse Control ◽  
Early Stage ◽  
Low Cost ◽  
Statistical Significance ◽  
Objective Assessment ◽  
Event Related Potential ◽  
Eeg Abnormalities

Abstract BackgroundPatients with Parkinson’s disease (PD) can develop the cognitive adverse effect of impulse control disorders (ICDs) while undergoing a pharmacological treatment for motor control dysfunctions with a dopamine agonist (DA). Conventional clinical interviews or questionnaires can be biased and may not provide an accurate diagnosis in the early stage. A wearable electroencephalogram (EEG)-sensing headset paired with an examination procedure can be a potential user-friendly method to explore ICD-related biomarkers that can reflect brain activity abnormalities and detect its early signs and progression.MethodsA stereotypical Go/NoGo test that targets impulse inhibition was performed with 59 individuals, including heathy controls, patients with PD, and patients with PD diagnosed with ICD. A low-cost LEGO-like EEG headset was used to record concurrent EEG signals. The event-related potential (ERP) analytical framework was then used to explore ICD-related EEG abnormalities after DA treatment.ResultsOnly PD patients with ICD exhibited a tendency for N2 and P3 amplitude deterioration at the fronto-central regions (i.e., Fz, FCz, and Cz); in particular, the P3 counterpart reached statistical significance (p<0.05). Neither PD patients nor healthy controls (without DA) replicated such findings. Furthermore, N2 amplitude deterioration was found to be related to ICD severity at Fz (r=-0.28, p=0.04).ConclusionsA low-cost LEGO-like EEG headset successfully captured ERP neuromarkers for the objective assessment of ICD in PD patients undergoing DA treatment. The present objective neuro-evidence could provide complementary information to conventional clinical scales used to diagnose the ICD adverse effect.

scholarly journals Exploring reward-related attention selectivity deficits in Parkinson’s disease

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Matthew J. D. Pilgrim ◽  
Zhen-Yi Andy Ou ◽  
Madeleine Sharp
Keyword(s):  
Parkinson’S Disease ◽  
Parkinson's Disease ◽  
Cognitive Processes ◽  
Search Task ◽  
Visual Search Task ◽  
Adaptive Modulation ◽  
Attention Capture ◽  
Reward Value ◽  
Automatic Attention ◽  
Reward Information

AbstractAn important aspect of managing a limited cognitive resource like attention is to use the reward value of stimuli to prioritize the allocation of attention to higher-value over lower-value stimuli. Recent evidence suggests this depends on dopaminergic signaling of reward. In Parkinson’s disease, both reward sensitivity and attention are impaired, but whether these deficits are directly related to one another is unknown. We tested whether Parkinson’s patients use reward information when automatically allocating their attention and whether this is modulated by dopamine replacement. We compared patients, tested both ON and OFF dopamine replacement medication, to older controls using a standard attention capture task. First, participants learned the different reward values of stimuli. Then, these reward-associated stimuli were used as distractors in a visual search task. We found that patients were generally distracted by the presence of the distractors but that the degree of distraction caused by the high-value and low-value distractors was similar. Furthermore, we found no evidence to support the possibility that dopamine replacement modulates the effect of reward on automatic attention allocation. Our results suggest a possible inability in Parkinson’s patients to use the reward value of stimuli when automatically allocating their attention, and raise the possibility that reward-driven allocation of resources may affect the adaptive modulation of other cognitive processes.

Sign in / Sign up

Export Citation Format

Share Document