scholarly journals Chronic administration of bifemelane hydrochoride increases somatostatin receptor binding in aged rat brain.

1991 ◽  
Vol 28 (1) ◽  
pp. 18-23 ◽  
Author(s):  
Hirohiko Sato ◽  
Kimunao Mizukawa ◽  
Norio Ogawa ◽  
Masato Asanuma ◽  
Haruhiko Takayama ◽  
...  
Keyword(s):  
Rat Brain ◽  
Receptor Binding ◽  
Somatostatin Receptor ◽  
Chronic Administration ◽  
Aged Rat

Effect of haloperidol withdrawal on somatostatin level and binding in rat brain

1990 ◽  
Vol 10 (1) ◽  
pp. 15-22 ◽  
Author(s):  
E. Perez-Oso ◽  
M. P. Lopez-Ruiz ◽  
E. Arilla
Keyword(s):  
Side Effects ◽  
Rat Brain ◽  
Specific Binding ◽  
Somatostatin Receptor ◽  
Somatostatin Receptors ◽  
Chronic Administration ◽  
Brain Areas ◽  
Frontoparietal Cortex ◽  
Receptor Number ◽  
Haloperidol Treatment

The effects of withdrawal on the level and specific binding of somatostatin in the frontoparietal cortex and hippocampus of the rat after chronic haloperidol treatment were examined using125I-Tyr11 somatostatin as tracer. One week after haloperiodol withdrawal the number of specific somatostatin receptors in both brain areas returned to control values, after having decreased as the result of chronic administration. Neither administration of haloperidol nor withdrawal of it affected the levels of somatostatin-like immunoreactivity (SLI) in the two brain areas studied. The return of the somatostatin receptor number to control values after haloperidol withdrawal may be related to the motor side-effects that are clinically observed when the haloperidol treatment is terminated.

Somatostatin-like immunoreactivity and somatostatin receptor binding in rat brain in pentylenetetrazol-induced kindling

Peptides ◽  
1988 ◽  
Vol 9 ◽  
pp. 105-107 ◽  
Author(s):  
Asla Pitkänen ◽  
Jukka Jolkkonen ◽  
Jouni Sirviö ◽  
Paavo Riekkinen
Keyword(s):  
Rat Brain ◽  
Receptor Binding ◽  
Somatostatin Receptor
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