scholarly journals Positive fluid balance in sepsis and its effects

2021 ◽  
Author(s):  
Deniz UYSAL SÖNMEZ ◽  
Hulya DİROL ◽  
Abdullah ERDOĞAN
Keyword(s):  
Fluid Balance ◽  
Positive Fluid Balance

Positive fluid balance and AKI diagnosis: assessing the extent and duration of ‘creatinine dilution’

2014 ◽  
Vol 41 (1) ◽  
pp. 160-161 ◽  
Author(s):  
John R. Prowle ◽  
Andrew Leitch ◽  
Christopher J. Kirwan ◽  
Lui G. Forni
Keyword(s):  
Fluid Balance ◽  
Positive Fluid Balance

Positive fluid balance is associated with increased in-hospital mortality in patients with intracerebral hemorrhage

Brain Injury ◽  
2018 ◽  
Vol 33 (2) ◽  
pp. 212-217
Author(s):  
Yanfei Shen ◽  
Xinmei Huang ◽  
Yongxia Hu ◽  
Weimin Zhang ◽  
Liquan Huang
Keyword(s):  
Intracerebral Hemorrhage ◽  
Hospital Mortality ◽  
Fluid Balance ◽  
Positive Fluid Balance

scholarly journals Mid-regional pro-adrenomedullin (MR-proADM), a marker of positive fluid balance in critically ill patients: results of the ENVOL study

Critical Care ◽  
2016 ◽  
Vol 20 (1) ◽  
Author(s):  
Bernard Vigué ◽  
Pierre-Etienne Leblanc ◽  
Frédérique Moati ◽  
Eric Pussard ◽  
Hussam Foufa ◽  
...  
Keyword(s):  
Critically Ill ◽  
Fluid Balance ◽  
Critically Ill Patients ◽  
Positive Fluid Balance

scholarly journals Association of Positive Fluid Balance and Mortality in Sepsis and Septic Shock in An Australian Cohort

2017 ◽  
Vol 45 (6) ◽  
pp. 737-743 ◽  
Author(s):  
M. G. Pittard ◽  
S. J. Huang ◽  
A. S. McLean ◽  
S. R. Orde
Keyword(s):  
Septic Shock ◽  
Hospital Mortality ◽  
Confidence Intervals ◽  
Fluid Balance ◽  
Severity Of Illness ◽  
Primary Outcome Measure ◽  
Published Data ◽  
Positive Fluid Balance ◽  
Retrospective Audit ◽  
Sepsis And Septic Shock

In patients with septic shock, a correlation between positive fluid balance and worsened outcomes has been reported in multiple observational studies worldwide. No published data exists in an Australasian cohort. We set out to explore this association in our institution. We conducted a retrospective audit of patient records from August 2012 to May 2015 in a single-centre, 24-bed surgical and medical intensive care unit (ICU) in Sydney, Australia. All patients with septic shock were included. Exclusion criteria included length of stay less than 24 hours or vasopressors needed for less than six hours. Data was gathered on fluid balance for the first seven days of ICU admission, biochemical data and other clinical indices. The primary outcome measure was survival to hospital discharge. One hundred and eighty-six patients with septic shock were included, with an overall hospital mortality of 23.7%. Seventy-five percent of patients required mechanical ventilation, and 27.4% required haemodialysis. The mean daily fluid balance on the first day of admission was positive 1,424 ml and 1,394 ml for ICU and hospital survivors, respectively. On average, the daily fluid balance for non-survivors was higher than the survivors: ICU non-survivors were 602 (95% confidence intervals 230, 974) ml (P=0.0015) and hospital non-survivors were 530 [95% confidence intervals 197, 863] ml (P=0.0017) higher than the survivors. In line with other recently published data, after adjustment for confounders (severity of illness based on the Acute Physiology and Chronic Health Evaluation score) we found a correlation between positive fluid balance and worsened hospital mortality in critically ill patients with sepsis and septic shock. Further research investigating rational use of fluids in this patient group is needed.

scholarly journals Hydration Efficacy of a Milk Permeate-Based Oral Hydration Solution

Nutrients ◽  
2020 ◽  
Vol 12 (5) ◽  
pp. 1502 ◽  
Author(s):  
Craig W. Berry ◽  
S. Tony Wolf ◽  
Bob Murray ◽  
W. Larry Kenney
Keyword(s):  
Fluid Balance ◽  
Urine Output ◽  
Mineral Content ◽  
Physiological Responses ◽  
Positive Fluid Balance ◽  
Oral Hydration ◽  
Time Points ◽  
Young Subjects ◽  
Milk Permeate ◽  
Time Point

Milk permeate is an electrolyte-rich, protein- and fat-free liquid with a similar carbohydrate and mineral content to that of milk. Its hydration efficacy has not been examined. The beverage hydration index (BHI) has been used to compare various beverages to water in terms of post-ingestion fluid balance and retention. Our purpose was to compare the BHI (and related physiological responses) of a novel milk permeate solution (MPS) to that of water and a traditional carbohydrate–electrolyte solution (CES). Over three visits, 12 young subjects consumed 1 L of water, CES, or MPS. Urine samples were collected immediately post-ingestion and at 60, 120, 180, and 240 min. BHI was calculated by dividing cumulative urine output after water consumption by cumulative urine output for each test beverage at each time point. The BHI for MPS was significantly higher at all time points compared to water (all p < 0.001) and CES (all p ≤ 0.01) but did not differ between CES and water at any time point. Drinking 1 L of MPS resulted in decreased cumulative urine output across the subsequent 4 h compared to water and CES, suggesting that a beverage containing milk permeate is superior to water and a traditional CES at sustaining positive fluid balance post-ingestion.

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