scholarly journals Isolation and Identification by Cytoprotection Assay of Antioxidative Compound Contained in Vinegar Produced from Sweet Potato-Shochu Post-Distillation Slurry

2010 ◽  
Vol 16 (4) ◽  
pp. 327-332 ◽  
Author(s):  
Kuniaki KAWANO ◽  
Shigeru MORIMURA ◽  
Emiko MORI ◽  
Hirokazu MATSUSHITA ◽  
Hiroto OHTA ◽  
...  
Keyword(s):  
Sweet Potato ◽  
Isolation And Identification ◽  
Antioxidative Compound

scholarly journals Trifostigmanoside I, an Active Compound from Sweet Potato, Restores the Activity of MUC2 and Protects the Tight Junctions through PKCα/β to Maintain Intestinal Barrier Function

2020 ◽  
Vol 22 (1) ◽  
pp. 291
Author(s):  
Amna Parveen ◽  
Seungho Choi ◽  
Ju-Hee Kang ◽  
Seung Hyun Oh ◽  
Sun Yeou Kim
Keyword(s):  
Tight Junctions ◽  
Sweet Potato ◽  
Barrier Function ◽  
Intestinal Barrier ◽  
Human Colon ◽  
Underlying Mechanism ◽  
Intestinal Barrier Function ◽  
Isolation And Identification ◽  
Human Colon Cancer ◽  
Mucin Production

Sweet potato (Ipomoea batata) is considered a superfood among vegetables and has been consumed for centuries. Traditionally, sweet potato is used to treat several illnesses, including diarrhea and stomach disorders. This study aimed to explore the protective effect of sweet potato on intestinal barrier function, and to identify the active compounds of sweet potato and their underlying mechanism of action. To this purpose, bioactivity-guided isolation, Western blotting, and immunostaining assays were applied. Interestingly, our bioactivity-guided approach enabled the first isolation and identification of trifostigmanoside I (TS I) from sweet potato. TS I induced mucin production and promoted the phosphorylation of PKCα/β in LS174T human colon cancer cells. In addition, it protected the function of tight junctions in the Caco-2 cell line. These findings suggest that TS I rescued the impaired abilities of MUC2, and protected the tight junctions through PKCα/β, to maintain intestinal barrier function.

scholarly journals Isolation and Identification of Antioxidative Compound from Fruit of Mengkudu (Morinda citrifoliaL.)

2007 ◽  
Vol 10 (2) ◽  
pp. 363-373 ◽  
Author(s):  
Z. Mohd Zin ◽  
A. Abdul Hamid ◽  
A. Osman ◽  
N. Saari ◽  
A. Misran
Keyword(s):  
Isolation And Identification ◽  
Antioxidative Compound

Batatins VII-X, glycolipid ester-type dimers from sweet potato (Ipomoea batatas)

Planta Medica ◽  
2012 ◽  
Vol 78 (11) ◽  
Author(s):  
D Rosas-Ramírez ◽  
R Pereda-Miranda
Keyword(s):  
Sweet Potato ◽  
Ipomoea Batatas
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