scholarly journals Analytical solution of the bioheat equation for thermal response induced by any electrode array in anisotropic tissues with arbitrary shapes containing multiple-tumor nodules

2019 ◽  
Vol 65 (3) ◽  
pp. 284
Author(s):  
E. J. Roca Oria ◽  
L. E. Bergues Cabrales ◽  
And J. Bory Reyes

The Pennes bioheat transfer equation is the most used model to calculate the temperature induced in a tumor when physical therapies like electrochemical treatment, electrochemotherapy and/or radiofrequency are applied. In this work, a modification of the Pennes bioheat equation to study the temperature distribution induced by any electrode array in an anisotropic tissue containing several nodules (primary or metastatic) with arbitrary shape is proposed. For this, the Green functions approach is generalized to include boundaries among two or more media. The analytical solution we obtain in a very compact way, under quite general suppositions, allows calculating the temperature distributions in the tumor volumes and their surfaces, in terms of heat sources, initial temperature and calorific sources at the boundary of tumors.

2013 ◽  
Vol 91 (7) ◽  
pp. 522-529
Author(s):  
B.S. Yilbas ◽  
A.Y. Al-Dweik

An analytical solution for lattice temperature distribution in a metallic solid subjected to laser short-pulse heating is presented. The method of similarity solution is adopted for the solution of the diffusive–ballistic energy equation. Volumetric and surface heat sources are each incorporated separately in the analysis. The material thermal response due to both heat sources during the short heating period is analyzed. It is found that a volumetric heat source resulted in smaller temperature increase in the irradiated material than a surface heat source, despite the same laser power intensity being used in both cases. This is attributed to energy transport mechanisms taking place in the solid substrate due to volumetric and surface heat sources.


Author(s):  
Ryan T. Roper ◽  
Matthew R. Jones

One of the most effective methods of treatment for cardiac arrhythmias is radio-frequency (RF) ablation. Many studies have shown that the tissue temperature distribution is the key factor influencing lesion shape and size, and that accurate prediction of this distribution is essential to the further improvement of the procedure. Temperature distributions can be obtained by solving the bioheat equation, which has been done in several studies using numerical techniques. This paper describes the development of an analytical solution that can be used as a bench mark for subsequent numerical solutions. Using integral transforms, the bioheat equation is reduced to an ordinary differential equation with time as the independent variable. The solution has the form of a surface integral within another surface integral. An integration routine that extends the trapezoidal method of integration in two dimensions to an analogous method in three dimensions has been developed in order to evaluate the analytical solution. A C program was written to implement this method, and the program was validated using a surface integral with a known analytical solution. The program was then used to generate temperature profiles at various time values and for different convection coefficients.


Author(s):  
Dário B. Rodrigues ◽  
Pedro J. d.S. Pereira ◽  
Paulo M. Limão-Vieira ◽  
Paolo F. Maccarini

2020 ◽  
Vol 10 (1) ◽  
Author(s):  
Hamdy M. Youssef ◽  
Najat A. Alghamdi

Abstract This work is dealing with the temperature reaction and response of skin tissue due to constant surface heat flux. The exact analytical solution has been obtained for the two-temperature dual-phase-lag (TTDPL) of bioheat transfer. We assumed that the skin tissue is subjected to a constant heat flux on the bounding plane of the skin surface. The separation of variables for the governing equations as a finite domain is employed. The transition temperature responses have been obtained and discussed. The results represent that the dual-phase-lag time parameter, heat flux value, and two-temperature parameter have significant effects on the dynamical and conductive temperature increment of the skin tissue. The Two-temperature dual-phase-lag (TTDPL) bioheat transfer model is a successful model to describe the behavior of the thermal wave through the skin tissue.


Open Physics ◽  
2020 ◽  
Vol 18 (1) ◽  
pp. 1084-1092
Author(s):  
Hongyun Wang ◽  
Wesley A. Burgei ◽  
Hong Zhou

Abstract Pennes’ bioheat equation is the most widely used thermal model for studying heat transfer in biological systems exposed to radiofrequency energy. In their article, “Effect of Surface Cooling and Blood Flow on the Microwave Heating of Tissue,” Foster et al. published an analytical solution to the one-dimensional (1-D) problem, obtained using the Fourier transform. However, their article did not offer any details of the derivation. In this work, we revisit the 1-D problem and provide a comprehensive mathematical derivation of an analytical solution. Our result corrects an error in Foster’s solution which might be a typo in their article. Unlike Foster et al., we integrate the partial differential equation directly. The expression of solution has several apparent singularities for certain parameter values where the physical problem is not expected to be singular. We show that all these singularities are removable, and we derive alternative non-singular formulas. Finally, we extend our analysis to write out an analytical solution of the 1-D bioheat equation for the case of multiple electromagnetic heating pulses.


2019 ◽  
Vol 8 (3) ◽  
pp. 64-75
Author(s):  
J. Kaur ◽  
S. A. Khan

The electromagnetic energy associated with microwave radiation interacts with the biological tissues and consequently, may produce thermo-physiological effects in living beings. Traditionally, Pennes’ bioheat equation (BTE) is employed to analyze the heat transfer in biological medium. Being based on Fourier Law, Pennes’ BTE assumes infinite speed of propagation of heat transfer. However, heat propagates with finite speed within biological tissues, and thermal wave model of bioheat transfer (TWBHT) demonstrates this non-Fourier behavior of heat transfer in biological medium. In present study, we employed Pennes’ BTE and TWMBT to numerically analyze temperature variations in human abdomen model exposed to plane microwaves at 2450 MHz. The numerical scheme comprises coupling of solution of Maxwell's equation of wave propagation within tissue to Pennes’ BTE and TWMBT. Temperatures predicted by both the bioheat models are compared and effect of relaxation time on temperature variations is investigated. Additionally, electric field distribution and specific absorption rate (SAR) distribution is also studied.  Transient temperatures predicted by TWMBT are lower than that by traditional Pennes’ BTE, while temperatures are identical in steady state. The results provide comprehensive understanding of temperature changes in irradiated human body, if microwave exposure duration is short.


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