Double-mass curves, with a section fitting curves to cyclic data

1960 ◽  
Keyword(s):  
Double Mass ◽  
Cyclic Data

scholarly journals Evaluation of external contamination on the vial surfaces of some hazardous drugs that commonly used in Chinese hospitals and comparison between environmental contamination generated during robotic compounding by IV: Dispensing robot vs. manual compounding in biological safety cabinet

2021 ◽  
pp. 107815522110235
Author(s):  
Hao ML ◽  
Wang T ◽  
Zhu JQ ◽  
Song YJ ◽  
Gong TJ ◽  
...  
Keyword(s):  
Environmental Contamination ◽  
High Performance ◽  
Surface Contamination ◽  
Comparison Analysis ◽  
Sample Analysis ◽  
Average Amount ◽  
External Contamination ◽  
Biological Safety ◽  
Double Mass ◽  
Hazardous Drugs

Objectives The aims of the study were to evaluate the external contamination of hazardous drug vials used in Chinese hospitals and to compare environmental contamination generated by a robotic intelligent dispensing system (WEINAS) and a manual compounding procedure using a biological safety cabinet (BSC). Methods Cyclophosphamide, fluorouracil, and gemcitabine were selected as the representative hazardous drugs to monitor surface contamination of vials. In the comparative analysis of environmental contamination from manual and robotic compounding, wipe samples were taken from infusion bags, gloves, and the different locations of the BSC and the WEINAS robotic system. In this study, high-performance liquid chromatography coupled with double mass spectrometer (HPLC-MS/MS) was employed for sample analysis. Results (1) External contamination was measured on vials of all three hazardous drugs. The contamination detected on fluorouracil vials was the highest with an average amount up to 904.33 ng/vial, followed by cyclophosphamide (43.51 ng/vial), and gemcitabine (unprotected vials of 5.92 ng/vial, protected vials of 0.66 ng/vial); (2) overall, the environmental contamination induced by WEINAS robotic compounding was significantly reduced compared to that by manual compounding inside the BSC. Particularly, compared with manual compounding, the surface contamination on the infusion bags during robotic compounding was nearly nine times lower for cyclophosphamide (10.62 ng/cm2 vs 90.43 ng/cm2), two times lower for fluorouracil (3.47 vs 7.52 ng/cm2), and more than 23 times lower for gemcitabine (2.61 ng/cm2 vs 62.28 ng/cm2). Conclusions The external contamination occurred extensively on some hazardous drug vials that commonly used in Chinese hospitals. Comparison analysis for both compounding procedures revealed that robotic compounding can remarkably reduce environmental contamination.

scholarly journals Identification of the Impacts of Climate Changes and Human Activities on Runoff in the Jinsha River Basin, China

2017 ◽  
Vol 2017 ◽  
pp. 1-9 ◽  
Author(s):  
Xiaowan Liu ◽  
Dingzhi Peng ◽  
Zongxue Xu
Keyword(s):  
Water Balance ◽  
River Basin ◽  
Human Activities ◽  
Climate Changes ◽  
Balance Method ◽  
Variation Method ◽  
Rainfall Runoff ◽  
Jinsha River ◽  
Water Balance Method ◽  
Double Mass

Quantifying the impacts of climate changes and human activities on runoff has received extensive attention, especially for the regions with significant elevation difference. The contributions of climate changes and human activities to runoff were analyzed using rainfall-runoff relationship, double mass curve, slope variation, and water balance method during 1961–2010 at the Jinsha River basin, China. Results indicate that runoff at upstream and runoff at midstream are both dominated by climate changes, and the contributions of climate changes to runoff are 63%~72% and 53%~68%, respectively. At downstream, climate changes account for only 13%~18%, and runoff is mainly controlled by human activities, contributing 82%~87%. The availability and stability of results were compared and analyzed in the four methods. Results in slope variation, double mass curve, and water balance method except rainfall-runoff relationship method are of good agreement. And the rainfall-runoff relationship, double mass curve, and slope variation method are all of great stability. The four methods and availability evaluation of them could provide a reference to quantification in the contributions of climate changes and human activities to runoff at similar basins in the future.

scholarly journals Inhomogeneity detection in the rainfall series for the Mae Klong River Basin, Thailand

2021 ◽  
Vol 11 (9) ◽  
Author(s):  
Alamgir Khalil
Keyword(s):  
River Basin ◽  
Curve Analysis ◽  
Rainfall Series ◽  
Rainfall Data ◽  
Homogeneity Test ◽  
Significance Level ◽  
Von Neumann ◽  
Standard Normal Homogeneity Test ◽  
Double Mass ◽  
Climate Studies

AbstractAn accurate and complete rainfall record is prerequisite for climate studies. The purpose of this research study was to evaluate the homogeneity of the rainfall series for the Mae Klong River Basin in Thailand. Monthly rainfall data of eight stations in the Mae Klong River Basin for the period 1971–2015 were used. The double mass curve analysis was used to check the consistency of rainfall data, whereas the absolute homogeneity was assessed using the Pettitt test, standard normal homogeneity test, Buishand test, and von Neumann test at a 5% significance level. The results of these tests were qualitatively classified as ‘useful’, ‘doubtful’, and ‘suspect’ according to the null hypothesis. Results of the monthly time series indicated the rainfall data as ‘useful’ for 75% of the stations, while two stations’ data were classified as ‘doubtful’ (Stn130221) and ‘suspect’ (Stn376401). On an annual scale, seven out of eight stations data were classified as ‘useful,’ while one station (Stn376401) data were classified as ‘suspect’. Double mass curve analysis technique was used for the adjustment of inhomogeneous data. The results of this study can help provide reliable rainfall data for climate studies in the basin.

Double-Mass Analysis on the Computer

1968 ◽  
Vol 94 (1) ◽  
pp. 139-142
Author(s):  
Rameshwar Singh
Keyword(s):  
Mass Analysis ◽  
Double Mass

scholarly journals Phonon–particle coupling effects in odd–even double mass differences of magic nuclei

JETP Letters ◽  
2016 ◽  
Vol 103 (1) ◽  
pp. 1-7 ◽  
Author(s):  
E. E. Saperstein ◽  
M. Baldo ◽  
N. V. Gnezdilov ◽  
S. V. Tolokonnikov
Keyword(s):  
Coupling Effects ◽  
Double Mass

Importance of oscillations in alveolar gas concentrations in the analysis of rebreathing data

1986 ◽  
Vol 61 (3) ◽  
pp. 1104-1113 ◽  
Author(s):  
K. H. Weisiger ◽  
G. D. Swanson
Keyword(s):  
Time Course ◽  
Continuous Process ◽  
Inert Gases ◽  
Accurate Estimation ◽  
Gas Solubility ◽  
Estimation Errors ◽  
Gas Uptake ◽  
Cyclic Model ◽  
Low Solubility ◽  
Cyclic Data

Cyclic rebreathing of a soluble inert gas can be used to estimate lung tissue volume (Vt) and pulmonary blood flow (Qc). A recently proposed method for analyzing such cyclic data (Respir. Physiol. 48: 255–279, 1982) mathematically assumes that ventilation is a continuous process. However, neglecting the cyclic nature of ventilation may prevent the accurate estimation of Vt and Qc. We evaluated this possibility by simulating the uptake of soluble inert gases during rebreathing using a cyclic model of gas exchange. Under cyclic uptake conditions alveolar gases follow an oscillating time course, because gas concentrations tend to increase during inspiration and to decrease during expiration. We found that neglecting these alveolar gas oscillations leads to the underestimation of soluble gas uptake by blood, particularly during the early rebreathing breaths. When continuous ventilation is assumed Vt and Qc are overestimated unless rapid rebreathing rates, large tidal volumes, and gases of moderately low solubility are used. Under these conditions the amplitude of the cyclic oscillations is minimized, the alveolar time course more closely resembles that expected from continuous ventilation, and the resulting errors are minimized. Alternatively, when the effect of oscillating alveolar gas concentrations on mass transfer are considered, these estimation errors can be eliminated without restricting rebreathing rate or gas solubility. We conclude that failure to consider the effect of cyclic rebreathing on the time course of alveolar gas concentrations may result in significant errors when evaluating rebreathing data for Vt and Qc.

A multivariate solution for cyclic data, applied in modelling locomotor forces

1987 ◽  
Vol 56 (1) ◽  
pp. 1-9 ◽  
Author(s):  
W. G. S. Hines ◽  
R. J. O'Hara-Hines ◽  
J. D. Brooke
Keyword(s):  
Cyclic Data
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