Distribution and sources of polychlorinated biphenyls in Woods Inlet, Lake Worth, Fort Worth, Texas, 2003

Soon after 9/11 a research project to study new immigration into the Dallas Fort Worth metropolitan area got under way. In the questionnaire that was administered to 600 immigrants across five different immigrant populations (Asian Indians, Vietnamese, Mexicans, Salvadorans, and Nigerians) between 2003 and 2005 we decided to include a question about the impact of 9/11 on their lives. We asked: “How has the attack on the World Trade Center on September 11, 2001 affected your position as an immigrant in the United States?” This article analyzes the responses to this question, looking at similarities and differences across different immigrant populations. It also addresses the broader issue of how 9/11 has affected both immigration policy and attitudes toward the foreign-born in the United States.

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Serum Dioxins and Polychlorinated Biphenyls Are Associated With Growth Among Russian Boys

PEDIATRICS ◽

10.1542/peds.2009-3556d ◽

2010 ◽

Vol 127 (2) ◽

pp. peds.2009-3556d-peds.2009-3556d

Keyword(s):

Polychlorinated Biphenyls

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Fatty Liver and Impaired Hepatic Metabolism Alters the Congener-Specific Distribution of Polychlorinated Biphenyls (PCBs) in Mice with a Liver-Specific Deletion of Cytochrome P450 Reductase

10.26434/chemrxiv.12026904.v1 ◽

2020 ◽

Author(s):

Xueshu Li ◽

Chun-Yun Zhang ◽

Hans-Joachim Lehmler

Keyword(s):

Cytochrome P450 ◽

Polychlorinated Biphenyls ◽

Fatty Liver ◽

Partition Coefficients ◽

Hepatic Metabolism ◽

Gas Chromatography Mass Spectrometry ◽

Cytochrome P450 Reductase ◽

P450 Reductase ◽

Specific Distribution ◽

Specific Deletion

Polychlorinated biphenyls (PCBs) are persistent organic pollutants that are linked to adverse health outcomes. PCB tissue levels are determinants of PCB toxicity; however, it is unclear how factors, such as an altered metabolism and/or a fatty liver, affect PCB distribution in vivo. We determined the congener-specific disposition of PCBs in mice with a liver specific deletion of cytochrome P450 reductase (KO), a model of fatty liver with impaired hepatic metabolism, and wildtype (WT) mice. Male and female KO and WT mice were exposed orally to Aroclor 1254, a technical PCB mixture. PCBs were quantified in adipose, blood, brain and liver tissues by gas chromatography-mass spectrometry. PCB profiles and levels in tissues were genotype and sex dependent. PCB levels were higher in the liver from KO compared to WT mice. PCB profiles showed clear differences between tissues from the same exposure group. While experimental tissue : blood partition coefficients in KO and WT mice did not follow the trends predicted using a composition-based model, the agreement between experimental and calculated partition coefficients was still reasonable. Thus, a fatty liver and/or an impaired hepatic metabolism alter the distribution of PCBs in mice and the magnitude of the partitioning of PCBs from blood into tissues can be approximated using composition-based models.<br>

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Determination of Polychlorinated Biphenyls (PCB) in Insulating Fluids

Industrial laboratory Diagnostics of materials ◽

10.26896/1028-6861-2017-83-11-15-20 ◽

2017 ◽

Vol 83 (11) ◽

pp. 15-20

Author(s):

E. S. Brodskii ◽

◽

A. A. Shelepchikov ◽

G. A. Kalinkevich ◽

E. Ya. Mir-Kadyrova ◽

...

Keyword(s):

Polychlorinated Biphenyls

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