scholarly journals Severe Haemolytic Anaemia, a Rare Presentation of Nutritional Vitamin B12 Deficiency: A Case Report

2019 ◽  
Vol 2 (1) ◽  
pp. 188-190
Author(s):  
Aamir Siddiqui
Keyword(s):  
Case Report ◽  
Vitamin B12 ◽  
Hemolytic Anemia ◽  
Megaloblastic Anemia ◽  
Vitamin B12 Deficiency ◽  
Pernicious Anaemia ◽  
Rare Form ◽  
Rare Presentation ◽  
B12 Deficiency ◽  
Nutritional Vitamin

Vitamin B12 deficiency usually presents with megaloblastic anemia, pancytopenia, and neurological symptoms. The cause is usually, nutritional deficiency, increase demand, decrease absorption. This report describes a case with symptoms of apathy and findings suggestive of severe hemolytic anemia, diagnosed with vitamin B12 deficiency. Haemolysis is a rare hematological finding in cases of B12 deficiency, and descriptions of a nutritional vitamin B12 deficiency, without evidence of pernicious anaemia, causing haemolysis, are even scarcer, and this paper was intended to draw physicians’ attention to this rare form of presentation.

scholarly journals Knuckle Pigmentation as an Early Cutaneous Sign of Vitamin B12 Deficiency: A Case Report

2020 ◽  
Vol 58 (230) ◽  
Author(s):  
Ankita Srivastava ◽  
Sanjiv Choudhary
Keyword(s):  
Case Report ◽  
Vitamin B12 ◽  
Oral Therapy ◽  
Megaloblastic Anemia ◽  
Vitamin B12 Deficiency ◽  
Neurological Complications ◽  
Neurological Deficits ◽  
B12 Deficiency ◽  
Systemic Manifestations ◽  
Nutritional Vitamin

Vitamin B12 deficiency can present with variable hematological, neuropsychiatric, and mucocutaneous changes. Hyperpigmentation, specifically involving the knuckles has been described in vitamin B12 deficiency, but usually,these patients are symptomatic with systemic manifestations like megaloblastic anemia, pancytopenia, or neurological deficits. Here, we are reporting a case of nutritional vitamin B12 deficiency, who presented with isolated knuckle pigmentation and was successfully treated with oral therapy. This case also highlights the importance of recognizing this cutaneous sign as an early marker of vitamin B12 deficiency; thereby enabling the clinician to treat the disease before it leads to irreversible neurological complications.

Microangiopathic Hemolytic Anemia – A Rare Presentation of Vitamin B12 Deficiency

2017 ◽  
Vol 85 (4) ◽  
pp. 322-324
Author(s):  
K. Jagadish Kumar ◽  
Divya Chowdary ◽  
Akshatha U. Shetty ◽  
C. Anitha
Keyword(s):  
Vitamin B12 ◽  
Hemolytic Anemia ◽  
Vitamin B12 Deficiency ◽  
Microangiopathic Hemolytic Anemia ◽  
Rare Presentation ◽  
B12 Deficiency

scholarly journals Transient vitamin B12 deficiency of maternal cause: case report

2020 ◽  
Vol 10 (3) ◽  
Author(s):  
Ludmila Feitosa ◽  
Danilo Pereira ◽  
Marianna Maia ◽  
Maria Fernandes Neta ◽  
Nahara Jurema ◽  
...  
Keyword(s):  
Case Report ◽  
Vitamin B12 ◽  
Methylmalonic Acid ◽  
Megaloblastic Anemia ◽  
Vitamin B12 Deficiency ◽  
Serum Levels ◽  
Animal Origin ◽  
B12 Deficiency ◽  
Meat And Eggs ◽  
Low Serum

Vitamin B12 or cyanocobalamin is obtained from the intake of food of restricted animal origin, especially milk, meat and eggs. During pregnancy, the fetus reserves vitamin B12 in the liver. This reserve is able to provide the needs of this vitamin in the first months of life. Our case refers to a 6-month-old infant in exclusive breastfeeding, who started a picture of loss of neuropsychomotor development, associated with hypotonia and megaloblastic anemia. Exams showed low serum levels of vitamin B12 and increased values of methylmalonic acid and homocysteine. Maternal research was performed, even if asymptomatic and without reports of comorbidities. Patient presented progressive improvement with vitamin B12 replacement, which was subsequently suspended, remaining only with the diet and with good evolution.

A case report on Subacute Combined Degeneration of spinal cord in children – A rare neurological manifestation in Vitamin B12 deficiencies

2017 ◽  
Vol 6 (12) ◽  
pp. 5562
Author(s):  
Tiana Mary Alexander ◽  
Vineeta Pande ◽  
Sharad Agarkhedkar ◽  
Dnyaneshwar Upase
Keyword(s):  
Spinal Cord ◽  
Case Report ◽  
Vitamin B12 ◽  
Pernicious Anemia ◽  
Chronic Diarrhea ◽  
Megaloblastic Anemia ◽  
Vegetarian Diet ◽  
Malabsorption Syndrome ◽  
Subacute Combined Degeneration ◽  
B12 Deficiency

Megaloblastic anemia is a common feature between 6 months – 2 years and rarely occurs after 5 years of age, especially in a child consuming non-vegetarian diet. B12 deficiency may occur after 5 years of age because of chronic diarrhea, malabsorption syndrome, or intestinal surgical causes. Pernicious anemia causes B12 deficiency, but nutritional B12 deficiency with subacute combined degeneration causing ataxia is rare.

Glossodynia as an Unusual Manifestation of Vitamin B12 Deficiency -A case report-

2006 ◽  
Vol 19 (2) ◽  
pp. 275 ◽  
Author(s):  
Jung Hun Lee ◽  
Il Man Jeong ◽  
Won Goo Seo ◽  
Chul Ho Woo ◽  
Jong Seok Bae ◽  
...  
Keyword(s):  
Case Report ◽  
Vitamin B12 ◽  
Vitamin B12 Deficiency ◽  
Unusual Manifestation ◽  
B12 Deficiency

The Danger of B12 Deficiency in the Elderly

1998 ◽  
Vol 12 (4) ◽  
pp. 215-226 ◽  
Author(s):  
Margaret Wynn ◽  
Arthur Wynn
Keyword(s):  
Nervous System ◽  
Risk Factor ◽  
Heart Disease ◽  
Vitamin B12 ◽  
Vitamin B12 Deficiency ◽  
Pernicious Anaemia ◽  
The Elderly ◽  
Nerve Cells ◽  
Accelerated Ageing ◽  
B12 Deficiency

Vitamin B12 deficiency damages nerve cells and aggravates nervous system disorders even in the absence of evidence of anaemia. Prevalence of B12 deficiency increases with age especially over 65 and is frequently associated with Alzheimer's disease. Recent American surveys record a higher prevalence of B12 deficiency and of undiagnosed and untreated pernicious anaemia in the elderly than reported earlier. B12 deficiency is also reported to be a risk factor for heart disease, stroke and accelerated ageing.

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