scholarly journals Diabetes Mellitus And Glycosylated Hemoglobin A1c

2018 ◽  
Vol 1 (2) ◽  
pp. 112-117
Author(s):  
Shiva Raj KC

Diabetes mellitus is a global health problem in 21st century. The incidence of diabetes mellitus is in rise and is estimated to be more prevalent in coming years. It is becoming one of the most common non-infectious and non-neoplastic causes of morbidity and mortality. Various complications are associated with diabetes mellitus. With control of blood glucose level, complications of diabetes mellitus can be minimized. In different time frame, different parameters and level have been used to diagnose diabetes. Glycosylated hemoglobin A1c is one of the reliable indicator of chronic hyperglycemia. In 2011, World Health Organization has included HbA1c in the diagnostic criteria. Various methods are used to detect the level of HbA1c.  Glycosylated hemoglobin is being used in the management of diabetes mellitus. Various studies have shown its prognostic implication in micro and macrovascular complications. Here we discuss various methods of estimation of HbA1c, various role of HbA1c in the management of Diabetes Mellitus and limitation of the test.  

2021 ◽  
Vol 17 (2) ◽  
pp. 107-114
Author(s):  
Sadik Jaafar Shukur ◽  
Wijdan Akram Hussein ◽  
Nazik L. Kadhum

Background: Diabetes is defined by the World Health Organization as a metabolic disorder characterized by chronic hyperglycemia with disturbances of carbohydrate, fat and protein metabolism resulting from defects in insulin secretion, insulin action, or both. Families are co-regulating systems in which the stresses and strains of one family member affect the well-being of another member of the family. Caregivers of children with chronic illness report experiencing more parental stress than parents of healthy children. Objective: A descriptive cross-sectional study had been conducted in four centers of endocrine diseases in Baghdad city and data was collected by using self-administered questionnaire regarding quality of life adapted from World Health Organization. The study was conducted on six hundred participants. Data analysis was done by using frequency, percentage and mean and analytical statistics using Chi Square test.  P value less than 0.05 was considered statistically significant. Results: The study showed that social domain had the highest mean score of (51.1) and that environmental domain had the lowest mean score of (38.9). The physical domain’s mean score was (40.2), while mean score of psychological domain was (46.2). The study reported that mothers of children with type 1 diabetes mellitus were more affected than fathers in physical, psychological and environmental domains. There was no difference between mothers and fathers in social domain of quality of life. Conclusion: It was concluded from the study that parents of diabetic children had generally poor quality of life that merits further investigations.


2014 ◽  
Vol 67 (1-2) ◽  
pp. 49-54 ◽  
Author(s):  
Mirjana Janicijevic-Petrovic ◽  
Biljana Veljkovic ◽  
Katarina Janicijevic ◽  
Tatjana Sarenac-Vulovic

Introduction. Diabetes mellitus is as old as the human race. Retinopathy, being one of complications of diabetes mellitus, is the most common cause of blindness. This study was aimed at analyzing the correlation between retinopathy and duration of disease, metabolic control, and obesity. Material and Methods. The study sample consisted of 135 patients divided into the experimental group of 90 patients with retinopathy and the control group of 45 patients without retinopathy. The patients were examined according to standard protocols: anamneses, endocrinology, ophthalmology exams, biochemical analyses, and anthropometric measurements. Results. The average age of patients was 60.13 ? 9.29 in the experimental group, while it was 57.55 ? 4.85 in the control group. The average duration of disease was 11.71 ? 5.8 and 14.40 ? 7.68 in the control group experimental group, respectively. The following statistically essential differences between the control and experimental group were found: in duration of disease (11.71 ? 5.85; 14.40 ? 7.68; r = 0.000), in glycemia (7.02 ? 2.20; 8.34 ? 3.18; p = 0.000), in glycosylated hemoglobin A1C (HbA1C) (7.16 ? 1.37; 8.22 ? 2.05; r = 0.000), in triglycerides (1.92 ? 0.72; 2.63 ? 1.60; r = 0.001), and in body mass index (23.94 ? 2.65; 27.66 ? 15.13; r = 0.000). Conclusion. There is a positive correlation between duration of disease, glycosylated hemoglobin A1C, triglycerides, body mass index - obesity and retinopathy. A significant statistical correlation among those parameters has been found in patients with diabetic retinopathy.


2021 ◽  
Vol 10 (11) ◽  
pp. 2357
Author(s):  
George Psillas ◽  
Grigorios G. Dimas ◽  
Anastasia Sarafidou ◽  
Triantafyllos Didangelos ◽  
Vasilios Perifanis ◽  
...  

The aim of this study is to evaluate the effects of diabetes mellitus, hypertension and hypercholesterolemia on the clinical presentation and outcome of Bell’s palsy. The study (comorbidity) group consisted of 50 patients with Bell’s palsy associated with diabetes, hypertension, or hypercholesterolemia; the control group included 46 patients with Bell’s palsy, but without comorbid diseases. The House–Brackmann grading system (I to VI) was used in order to assess the initial and final facial functions. Both groups of patients were treated with steroids and the antiviral agent acyclovir. The mean severity of initial facial paralysis was more significant in diabetes, hypercholesterolemia, and hypertension, in comparison to the control group. Patients suffering from Bell’s palsy and concomitant comorbidities have a poorer prognosis (HB III-VI) compared to patients without comorbidities. Increased glycosylated hemoglobin A1c levels (>6.7%) were significantly correlated with unsatisfactory facial recovery. The pathogenetic mechanisms by which diabetes, hypercholesterolemia, and hypertension affect the vasa nervosum of facial nerve have been described.


2020 ◽  
pp. 18-27
Author(s):  
Lotfi RAHAL ◽  
Youcef BOUCHEDOUB

The relationships between nutrition and immunity have been the subject of several studies. The main fact lies in the deep entanglement between immunity, and nutritional state: all deficiencies in proteins, essential fatty acids, metallo-enzymes, vitamin factors, and antioxidant elements lead to a dysfunction of the immune system. On the other hand, some excess food (total lipid intake, type of fatty acids, simple sugars, etc.) can, also, have deleterious effects. The emergence of new infectious diseases with new pathogenic properties is a serious global health problem. Covid-19 infection (Coronavirus Disease-2019) caused by the coronavirus SARS-CoV2 (Severe Acute Respiratory Syndrome Coronavirus-2), is recognized as pandemic by the World Health Organization (WHO).This implies strict prevention measures, and a strategy to be developed throughout good hygiene, healthy and balanced diet, and compliance with the con-finement rules.


Author(s):  
Lara Bittmann

On December 31, 2019, WHO was informed of cases of pneumonia of unknown cause in Wuhan City, China. A novel coronavirus was identified as the cause by Chinese authorities on January 7, 2020 and was provisionally named "2019-nCoV". This new Coronavirus causes a clinical picture which has received now the name COVID-19. The virus has spread subsequently worldwide and was explained on the 11th of March, 2020 by the World Health Organization to the pandemic.


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