scholarly journals Prolonged Coma after Pituitary Macro- adenoma Surgery: A Case Report with Short Literature review

2019 ◽  
Vol 21 (3) ◽  
pp. 244-248
Author(s):  
M. Karki ◽  
A.J. Thapa ◽  
Yam Bahadur Roka

Prolonged coma after surgery of pituitary macro-adenoma with apoplexy, often previously unnoticed, is rare and not well reported complication. A 65 year male presented with complaints of headache and blurred vision since few months. Brain MRI was done and it reported macro- adenoma with pituitary apoplexy. Right pterional craniotomy was done following total excision of tumor. Patient developed whole body seizure at first day of surgery and went to prolonged coma.

Skull Base ◽  
2010 ◽  
Vol 20 (04) ◽  
pp. 285-288 ◽  
Author(s):  
Sandeep Mohindra ◽  
Priyamvada Kovai ◽  
Rajesh Chhabra

1998 ◽  
Vol 45 (3) ◽  
pp. 393-398 ◽  
Author(s):  
FUMIO OTSUKA ◽  
JINGO KAGEYAMA ◽  
TOSHLO OGURA ◽  
HIROFUMI MAKINO

2016 ◽  
Vol 11 (2) ◽  
pp. 189-191 ◽  
Author(s):  
Michael B. Centorino ◽  
Glenn Catalano ◽  
Maria C. Catalano

2019 ◽  
Vol 25 (3) ◽  
pp. 26
Author(s):  
Jean-François Sergent ◽  
Gérard Bader ◽  
Julien Hamon ◽  
Lucie Peigne ◽  
Sophie Lejeune

Introduction: Desomorphine is an opioid formerly used to treat acute pain. It is simple to manufacture, which has recently led to an increase in its clandestine production under the name “Krokodil”. This article presents a case of oral problems related to its use first ever reported in France. Observation: A 36-year-old male patient presented with bone exposure in sector 1. He admitted to actively consuming “Krokodil IV” for several years. In the course of the clinical and radiological examinations, the patient was diagnosed with osteochemonecrosis of the maxillary induced by krokodil, considering that severe intrinsic and extrinsic adverse effects have been attributed to the drug. Discussion: A systematic literature review was conducted using articles from the Medline and Web of Science databases. To treat such a condition, two authors have described a process consisting of total excision of the necrotic tissue with 0.5 cm margins, combined with discontinuing the intake of the drug. However, these observations should be considered with caution because of the absence of any prospective studies. Conclusion: There are a number of etiologies for osteonecrosis in the context of radiotherapy, intake of bisphosphonates, and administration of bone resorption inhibitors. Unfortunately, in the case of krokodil, its high addictive nature makes it difficult for the patient to wean off the drug. Further, the heterogeneity of its manufacturing make it challenging to pharmacokinetically analyze its prolonged use. In view of the current literature, surgical therapy associated with weaning appears to be the most appropriate treatment, without being able to rule out addiction or necrotic relapses.


2016 ◽  
Vol 40 (1) ◽  
pp. 180-182 ◽  
Author(s):  
Kaiser Hussain ◽  
Thomas J. Walsh ◽  
J. Levi Chazen

2020 ◽  
Vol 141 ◽  
pp. 73-80
Author(s):  
Turki Elarjani ◽  
Stephanie Chen ◽  
Iahn Cajigas ◽  
Brian Saway ◽  
Samir Sur ◽  
...  

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