scholarly journals Filariasis Diagnosed by Real Time Sonographic Imaging as Filarial Dance Sign: A Case Report

2019 ◽  
Vol 21 (2) ◽  
pp. 160-163
Author(s):  
Sumiran Shrestha ◽  
R. Shrestha ◽  
S. Gokhale

 Lymphatic filariasis is a major public health problem. World Health Organization (WHO) has graded filariasis, as the second leading cause for permanent and long-term disability after leprosy. It is a chronic disabling parasitic disease prevalent in South Asia and Africa. A case of 26-year-old male resident of district Palpa presented with swelling of left inguinal region since 3-4 days and pain in inguinal region since a month. He had no history of trauma, fever or any other systemic symptoms. High frequency, high-resolution scrotal ultrasonography is a valuable technique for diagnosing scrotal filarial infection. This method revealed “Filarial Dance Sign” which is a distinctive and continuous pattern of movement of live microfilaria indicating active infection. It is a simple, rapid, sensitive and noninvasive technique. Noninvasive ultrasonography is preferable to the invasive FNAC.

Author(s):  
Sunil Kumar Kasundriya ◽  
Mamta Dhaneria ◽  
Aditya Mathur ◽  
Ashish Pathak

Childhood pneumonia is a major public health problem. The aim of this prospective hospital-based study is to determine the incidence and risk factors for community-acquired severe pneumonia in children in Ujjain, India. The study includes 270 children, 161 (60%) boys and 109 (40%) girls, aged between 2 months and 5 years with World Health Organization defined and radiologically confirmed severe pneumonia. Considering the 270 children, 64% (95% confidence interval (CI) 57.9–69.4) have severe pneumonia. The following are identified as risk factors for severe pneumonia from the generalized logistic regression model: Born premature (adjusted odds ratio (AOR) 7.50; 95% CI 2.22–25.31; p = 0.001); history of measles (AOR 6.35; 95% CI 1.73–23.30; p = 0.005); incomplete vaccination (AOR 2.66; 95% CI 1.09–6.48; p = 0.031); acyanotic congenital heart disease (AOR 9.21; 95% CI 2.29–36.99; p = 0.002); home treatment tried (AOR 3.84; 95% CI 1.42–10.39; p = 0.008); living in a kuchha house (AOR 3.89; 95% CI 1.51–10.01; p = 0.027); overcrowding (AOR 4.50; 95% CI 1.75–11.51; p = 0.002);poor ventilation in living area (AOR 16.37; 95% CI 4.67–57.38; p < 0.001); and practicing open defecation (AOR 16.92; 95% CI 4.95–57.85; p < 0.001). Awareness of these risk factors can reduce mortality due to severe pneumonia.


2019 ◽  
Vol 8 ◽  
pp. 216495611985803 ◽  
Author(s):  
Deanna R Befus ◽  
Sharon Hull ◽  
Justine Strand de Oliveira ◽  
Gillian Sanders Schmidler ◽  
Morris Weinberger ◽  
...  

Background Migraine is a disabling neurological disorder and the sixth biggest cause of disability worldwide. The World Health Organization has declared migraine a major public health problem due to a paucity of knowledge about cause and effective treatment options. Both in incidence and severity, migraine disproportionately affects people occupying marginalized social locations (SL). Managed pharmacologically, migraine is treated with daily preventive and as-needed abortive medications. Both come with high literal and figurative costs: intolerable side effects, medication interactions, and prohibitive prices. Cost prohibitive, ineffective, and unsustainable pharmacological treatment options have contributed to high levels of interest in complementary approaches by people with migraine, but little is known about their motivations, patterns of use or access, or how these may vary by SL. Method We conducted focus groups with 30 people with migraine to explore their desires and recommendations for migraine clinicians and researchers. We used qualitative content analysis to identify themes. Outcomes: We identified 4 themes: a more holistic, collaborative, long-term treatment approach; medication as a short-term solution; high personal and economic costs of medication; and desire for more information and access to natural approaches. Across SL, participants expressed keen interest in integrative approaches and wanted better access to complementary modalities. Participants in marginalized SL described reliance on traditional/folk remedies, including engagement with family and community healers, who they described as more affordable and culturally accessible. Conclusions Holistic and integrative approaches were preferred over medication as long-term migraine management strategies. However, people in marginalized SL, while disproportionately disabled by migraine, did not feel as comfortable accessing integrative approaches through currently available channels. Engaging with these communities and using a critical lens to explore barriers to access can develop options to make complementary modalities more approachable, while also attending to systemic blind spots that may unintentionally alienate socially marginalized groups.


Nutrients ◽  
2021 ◽  
Vol 13 (11) ◽  
pp. 3832
Author(s):  
Amy Hofman ◽  
Marlou A. M. Limpens ◽  
Tosca O. E. de Crom ◽  
Mohammad Arfan Ikram ◽  
Annemarie I. Luik ◽  
...  

Physical inactivity is a major public health problem, and there are concerns this might have increased during the COVID-19 pandemic. We aimed to identify distinct trajectories of physical activity over a 6-week period after the first restrictive measures and to explore determinants of these trajectories in a population-based cohort of middle-aged and elderly in the Netherlands (n = 5777). We observed that at least 59% of participants did not meet the World Health Organization recommendations for physical activity. Using latent class trajectory analyses over three time points, we identified five distinct trajectories, including four steady trajectories at different levels (very low, low, medium and high) and one increasing trajectory. Using multinomial logistic regression analyses, we observed that, compared to the ‘steadily high’ trajectory, participants in the ‘steadily very low’ trajectory were more often older, lower educated, reporting poorer physical health, more depressive symptoms, consuming a less healthy diet, smoking, and lower alcohol use, and were less often retired. A similar pattern of determinants was seen for those in the increasing trajectory, albeit with smaller effect sizes. Concluding, we observed low levels of physical activity that generally remained during the pandemic. The determinants we described can help identify groups that require additional preventive interventions.


Author(s):  
Zubin Bhagwagar ◽  
George R. Heninger

Major depressive disorder is a serious, recurrent illness which levies a crippling toll on individuals, families, and society in general. The importance of depression as a major public health problem is emphasized by findings from the World Health Organization Global Burden of Disease survey in showing that in 1990 it was the fourth largest cause of burden of disease (i.e. years of life lost due either to premature mortality or to years lived with a disability). It has been estimated that by the year 2020 it is expected to be the second largest cause of burden of disease. Depression is underdiagnosed and frequently under-treated, and depressed individuals have a much higher risk for suicide. The primary treatment for depression involves the use of antidepressant drugs, and it is therefore important that clinicians become familiar with and adept in utilizing this important group of compounds. Although primarily used for the treatment of depression, drugs within this category also have a number of other important uses. A thorough understanding of the pharmacology of antidepressants will aid the clinician in the selective use of these drugs for patients with depression as well as patients with a number of other disorders.


Author(s):  
Luisa Costantini ◽  
Marco Marando ◽  
Pietro Gianella

Tuberculosis (TB) is a cause of ill health and death worldwide. Since 2010, the diagnostic process has strongly relied on GeneXpert assays on biological specimens. Xpert MTB/RIF is an automated nucleic acid amplification test (NAAT) for Mycobacterium tuberculosis and rifampicin resistance, endorsed by the World Health Organization and the US Food and Drug Administration. Xpert is used in many countries as the initial diagnostic test for tuberculosis. Nevertheless, the reliability of GeneXpert positive tests in patients with a history of TB is largely unknown, due to possible false-positive results (i.e., GeneXpert-positive but culture-negative patients). We present a case report of a patient with a history of pulmonary TB, who was GeneXpert positive but culture negative on bronchoalveolar lavage 22 months after completion of appropriate antitubercular therapy.


2011 ◽  
Vol 6 (03) ◽  
pp. 234-241 ◽  
Author(s):  
Abdirahman Sheikh Mahamud ◽  
Jamal A Ahmed ◽  
Raymond Nyoka ◽  
Erick Auko ◽  
Vincet Kahi ◽  
...  

Introduction: Cholera remains a major public health problem that causes substantial morbidity and mortality in displaced populations due to inadequate or unprotected water supplies, poor sanitation and hygiene, overcrowding, and limited resources. A cholera outbreak with 224 cases and four deaths occurred in Kakuma Refugee Camp in Kenya from September to December 2009. Methodology: We conducted a case-control study to characterize the epidemiology of the outbreak. Cases were identified by reviewing the hospital registry for patients meeting the World Health Organization (WHO) case definition for cholera. For each case a matched control was selected. A questionnaire focusing on potential risk factors was administered to cases and controls. Results: From 18 September to 15 December 2009, a total of 224 cases were identified and were hospitalised at Kakuma IRC hospital.  Three refugees and one Kenyan national died of cholera. V. cholerae O1, serotype Inaba was isolated in 44 (42%) out of 104 stool specimens collected. A total of 93 cases and 93 matched controls were enrolled in the study. In a multivariate model, washing hands with soap was protective against cholera (adjusted odds ratio [AOR] =0.25[0.09-0.71]; p < 0.01), while presence of dirty water storage containers was a risk factor (AOR=4.39[1.12-17.14]; p=0.03). Conclusion:  Provision of soap, along with education on hand hygiene and cleaning water storage containers, may be an affordable intervention to prevent cholera.


2020 ◽  
Vol 4 (2) ◽  

Introduction: Ophthalmia or neonatal conjunctivitis is a major public health problem in developing countries. Recommendations have been issued by the World Health Organization (WHO) and the Ministry of Health of Senegal for the prevention of this scourge. The objective of the work was to assess the level of knowledge and practice of these recommendations by health workers. Methodology: This was a multicenter, prospective study conducted from March 1st to June 30th, 2013 in nine (9) health structures at the four (4) districts of Dakar. All agents who performed care at birth were included. Results: We interviewed 108 health care workers in the nine targeted structures. More than half of the respondents (54.6%) interviewed were in a maternity ward with midwives (41.7%) who were clearly in the majority. As far as knowledge is concerned, the practice of neonatal eye care was systematic for 88% of the nursing staff at birth. Regarding attitudes and practices, the majority of caregivers cleaned (67.6%) the eyes before instillation of eye drops. More than eighty-four percent (84.3%) of the caregivers surveyed routinely practiced eye care in the newborn at birth. The majority of the agents prescribed Rifamycin (47.2%) as a single dose in each eye. Paediatricians recommended one day of treatment while midwives and general practitioners recommended 7 days. Conclusion: Overall, the recommendations are not well implemented by caregivers. It would then be necessary to improve the level of information for harmonization and application of the recommendations.


2020 ◽  
pp. 1-5
Author(s):  
Tamar Etzioni-Friedman ◽  
Amos Etzioni

Immunizations have been saving the lives of millions of people since they were first used by Edward Jenner in 1796, and new vaccines are being developed all the time. Hopefully, a new vaccine for coronavirus disease 2019 (COVID-19) will be developed in the near future, and perhaps even one for human immunodeficiency virus. Although the effectiveness of vaccinations has been proven over the years and adverse effects to currently available vaccinations are extremely rare, many people continue to defer immunizations for themselves and their families. According to the World Health Organization (WHO), this phenomenon, known as “vaccine hesitancy,” is a major public health problem globally. This review summarizes the unproven adverse effects of various vaccines and stresses the importance of enforcing vaccination policies to minimize vaccine hesitancy. Every effort should be made to improve existing vaccines and to produce new ones, according to carefully designed scientific preclinical and clinical trials. This is particularly important in today’s era, in light of the global transparency regarding vaccination development, and the potential for future pandemics such as COVID-19.


2013 ◽  
Vol 35 (2) ◽  
pp. 223 ◽  
Author(s):  
Anjum Hashmi ◽  
Jamil Ahmed Soomro ◽  
Khalid Saleem

The epidemic of obesity took off from about 1980 and in almost all countries has been rising inexorably ever since. Only in 1997 did world health organization accept that this was a major public health problem. It is also becoming an important public health problem among Pakistani children due to changes in life style and other factors. The increasing prevalence of childhood obesity and its concomitant health risks justify widespread efforts toward prevention. A Cross-sectional study was conducted to elaborate the various types of foods and change in eating behavior leading to abnormal weight gain among the youth. A total of 504 male and female students of class six to ten were selected through simple random sampling. Anthropometric measurements were done with calibrated instruments using the age and sex specific BMI cut off points according to World Health Organization growth reference. Results showed significant proportion of girls (86%) and boys (85%) had abnormal waist to hip ratio. The determinants of the obesity lie within the rapid changes in food intake behavior and lifestyle patterns which had a clear and significant impact on the prevalence of obesity in youth of Pakistan.


2015 ◽  
Vol 100 (3) ◽  
pp. 562-567 ◽  
Author(s):  
Hayato Yamauchi ◽  
Shinji Sakurai ◽  
Nobuhiro Nakazawa ◽  
Tomonori Yoshida ◽  
Yuichi Tabe ◽  
...  

Among neuroendocrine neoplasms, mixed exocrine and endocrine characteristics with at least 30% of each component are classified into mixed adenoneuroendocrine carcinoma (MANEC), according to the 2010 World Health Organization classification. We experienced a rare case of MANEC of the stomach with focal intestinal metaplasia and hypergastrinemia. A 76-year-old Japanese male was diagnosed as having gastric adenocarcinoma and underwent total gastrectomy. The pathologic diagnosis was MANEC of the stomach accompanied by unusual mucosal atrophy without Helicobacter pylori infection, the characteristics of which were different from both type A and type B atrophic gastritis. The patient has a history of long-term use of a proton pump inhibitor. Additional serum chemistry examination using preoperatively obtained plasma from the patient revealed hypergastrinemia. The mechanism of gastric MANEC carcinogenesis is still unclear, but that might be correlated with unusual intestinal metaplasia and hypergastrinemia in this case.


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