scholarly journals Relationship of Torch Profile in First Trimester Spontaneous Miscarriage

2016 ◽  
Vol 5 (2) ◽  
pp. 17-21
Author(s):  
Sabina Lamichhane ◽  
Shanti Subedi ◽  
Sita Pokharel Ghimire ◽  
Manisha Chetri ◽  
Basudev Banerjee

Background TORCH is a group of organisms like Toxoplasma, Rubella, Cytomegalo virus and Herpes simplex virus. These groups of organisms causing infections in pregnant lady leads to various degree of adverse pregnancy outcomes in the form of spontaneous abortion, preterm delivery, intrauterine growth restriction, severe congenital defect with syndromic babies. So, to observe the relationship of TORCH infection in first trimester spontaneous miscarriage in our population and to treat them, this study was performed.Materials and Methods A total of 103 patients with spontaneous abortion meeting inclusion criteria were taken in the study. TORCH profile was sent for those patients and observed the sero-prevalance for IgM and IgG. Thereafter organism was identified and the results were interpreted.Results Out of total 103 patients enrolled 58.25 % of patients were sero-positive for TORCH complex. IgM or IgG Sero-positive for Toxoplasma, Rubella, Cytomegalo virus and Herpes Simplex virus were 11.65% /17.47% ;7.76% / 43.68%; 19.41% / 41.74% and 31.06% / 54.36% respectively.Conclusion In the present study on analyzing the association of TORCH antibodies in women with spontaneous abortion, infection with Herpes simplex virus was most commonly associated.Journal of Nobel Medical College Vol.5(2) 2016; 17-21

1980 ◽  
Vol 10 (3) ◽  
pp. 555-557
Author(s):  
A. H. Reid ◽  
K. W. Martin ◽  
B. R. Ballinger ◽  
B. B. Heather

SYNOPSISThe relationship between herpes simplex virus type 1 and mental retardation is explored by studying the antibody levels to this virus in a group of 86 severely and profoundly retarded adults. A tendency towards higher antibody levels is found in patients whose retardation is of unknown aetiology. The relationship of these observations to previous research findings and the possible significance of herpes simplex virus in the aetiology of mental retardation are discussed


1996 ◽  
Vol 28 (5) ◽  
pp. 289-295 ◽  
Author(s):  
Mariko Akiba ◽  
Itsuro Yoshida ◽  
Tatsuo Suzutani ◽  
Masahiro Ogasawara ◽  
Masanobu Azuma

1988 ◽  
Vol 16 (3) ◽  
pp. 193-196 ◽  
Author(s):  
Marina Bujko ◽  
Vojin Šulovic ◽  
Vera Živanovic ◽  
Rajko Dotlić ◽  
Ivana Bardič

Author(s):  
Zainab A. Hamid ◽  
Solaf J. Ali ◽  
Ali Hattem Hussain

Among many viral causes of miscarriage, maternal infections caused by herpes simplex virus type -1 (HSV-1) and Herpes simplex virus type-2 (HSV-2) infections are important causes. CD14 was implicated in immune mechanisms, and might be involved in pregnancy loss.  The aim of this study was to detect the possible occurrence of two HSV-1 and HSV-2 infections as well as the immunological factor cd14 in placental tissues from patients with spontaneous abortion using immunohistochemistry techniques. Immunohistochemistry technique assay was used to detect placental infection with HSV-1& HSV-2 as well as CD14 in 40 women with spontaneous miscarriage and in 40 healthy deliveries in Baghdad/Iraq. The IHC- expressions of HSV-1, HSV-2, and CD14 proteins were detected in 4(10%), 15(37.5%), 15(37.5%) in placental tissues from miscarriage women, respectively. The association between CD14 with HSV-1 and HSV-2 among the placental tissues from miscarriage patients was constituting (5%), (20%) with HSV-1 & HSV-2, respectively. The considerable proportion of HSV-1, HSV-2, and infections found in the placental tissues from miscarriage women could drag the attention of obstetricians to implicate these viruses as possible targets in the etiology of spontaneous abortion case and there is possible association of CD14 with HSV-1 and HSV-2 in women with abortion.


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