scholarly journals Maternal And Fetal Outcome Following Severe Anaemia In Pregnancy: Results From Nobel Medical College Teaching Hospital, Biratnagar, Nepal.

2013 ◽  
Vol 2 (1) ◽  
pp. 22-26
Author(s):  
Ram Hari Ghimire ◽  
Sita Ghimire

Background: anaemia is a major contributor to maternal death in developing countries. Since it reduces resistance to blood loss, death may occur from bleeding associated with normal delivery. Objective: To explore the association between anaemia and maternal and perinatal complications. Study Design: Retrospective cohort study. Materials and Methods: 100 pregnant women admitted for delivery and having severe anaemia were studied and compared with 100 non anaemic women matched for age, parity, and gestational age. Adverse outcomes analysed were: pregnancy induced hypertension, Postpartum haemorrhage hypertension, Abruptio Placenta,, Infection, Maternal Mortality, Low Birth Weight, and Perinatal mortality. Results : Compared to nonexposed women, exposed women had an increased risk of pregnancy induced hypertension with odds ratio of 5.06 . Postpartum haemorrhage, incidence of wound infection,Intermediate care unit admission were statistically significant in exposed group .However there was no significant difference in maternal mortality among study group.APGAR score <7 in 5 minutes was 18%in exposed group and 5% in non exposed group (p=0.0039). Intrauterine fetal death was 6% in cases and none of respondants from control group had Intrauterine fetal death (p=0.0128). Frequency of low birth weight was 22% in exposed group and 9% in non exposed group(p=0.011). Conclusions: The burden of anemia in pregnant population is still high in eastern region of Nepal. Severe anemia in pregnancy carries significant risk to mother and fetus. Hence preventive measures need to be implemented at community level. Public awareness regarding pre-pregnancy hemoglobin status and importance of antenatal checkup relating with maternal and fetal adverse pregnancy outcome should be initiated. Journal of Nobel Medical College Vol. 2, No.1 Issue 3 Nov.-April 2013 Page 22-26 DOI: http://dx.doi.org/10.3126/jonmc.v2i1.7668

Author(s):  
Radhika S. Deshpande ◽  
Manvi M. R.

Background: Intra uterine fetal death (IUFD) is defined as the baby born with no signs of life at or after 28 weeks of gestation. It is important to diagnose the cause in order to avoid further recurrence and to treat any maternal associated factors. The aim of the present study was to calculate incidence of IUFD in our hospital and know the causes, mode of delivery, associated complications. So we can take measures to prevent them in future.Methods: The retrospective study was conducted in the department of Obstetrics and Gynecology in Kanachur Medical College, Mangalore from January 2017 to January 2020. The women with confirmed diagnosis of IUFD on Ultrasound and beyond 28 weeks of gestation were included in the study.Results: In the study period, total 2026 patients delivered, of which 40 cases were IUFD, hence our incidence rate was 19.74 per 1000 population. 62.5% cases were multigravida. 15% had previous history of abortions while 5% previously had IUFD. In 37.5% cases, the cause was unknown, followed by 22.5% having pregnancy induced hypertension. Anemia contributed to 17.5% and placental causes in 12.5%. 10% of the women had PPH. One patient had sepsis, followed by acute renal failure and later died of multi organ failure.Conclusions: All the causes are not preventable, many of them can be identified early in pregnancy and thus IUFD can be prevented. All the high risk pregnancies should undergo antenatal fetal surveillance and should have frequent ante natal visits to reduce IUFD rates.


2014 ◽  
Vol 5 (2) ◽  
Author(s):  
Olusola Funmilayo Sotunde ◽  
Silifat Ajoke Sanni ◽  
Oluseye Olusegun Onabanjo ◽  
Ibiyemi O. Olayiwola ◽  
Mure Agbonlahor

Our study assessed the health profile of neonates in relation to anemia in pregnancy and pregnancy induced hypertension (PIH). This was a retrospective study where a systematic random sampling technique was used to select a total of 1046 case records of pregnant women registered for ante-natal care at Lagos Island Maternity Hospital, Lagos, Nigeria, between 2005 and 2009. Socio-demographic characteristics of the mothers, prevalence of anemia and PIH, and neonatal health profile were obtained from the case records and were analyzed using both descriptive and inferential statistics. Pearson product moment correlation was used to show the relationship (P≤0.05) between maternal complications and neonatal health profile. Majority (68.8%) of the mothers had anemia and 6.7 % had PIH. Majority (97.12%) of the neonates were live births and 2.88% of the neonates were still births, 65.4% of the women with still birth pregnancy outcome had anemia, and 34.6% had PIH. Majority (74%) of the neonates had birth weight within normal range (2.5-4.0 kg) and majority (68%) had normal Apgar score at 5 min of birth (7- 10). A positive correlation existed between the packed cell volume of the mother and the birth weight of the neonates (r=0.740, P≤0.05). A negative correlation existed between the incidence of PIH and the birth weight of the neonates (r=


2018 ◽  
Vol 2 (3) ◽  
pp. 255-259
Author(s):  
Santoshi Shrestha Pradhan ◽  
Sabitra Paudel ◽  
Puspa Parajuli ◽  
Bina Rana Khagi

Introduction: Hypertensive disorders seem to complicated in approximately 5-15% of pregnancies. Pregnancy induced hypertension (PIH) increases the risk of maternal and perinatal morbidity and mortality.Objective: To assess the neonatal outcome and to identify the association between the demographic variables and outcome of Pregnancy Induced Hypertension in antenatal ward of Kathmandu Medical College and Teaching Hospital.Methodology: Prospective study design was conducted for the study in Obstetrics ward of Kathmandu Medical College Teaching Hospital. The population was the 100 antenatal mothers with pregnancy induced hypertension admitted in antenatal ward and purposive convenient sampling technique was used to collect the data. The structured questionnaire was designed and the data was collected through interview technique from 1st February 2014 to 10 March 2016. The collected data was analyzed using SPSS programme.Results: Regarding neonatal outcome the findings of the study showed that most of the babies 83% had normal weight. The most of the babies 82% had adequate for gestational age. Regarding Apgar score half of the babies 50% scored mild asphyxia at the first minute whereas most of the babies 93% scored no asphyxia at five minutes after delivery. Regarding perinatal outcome 13% babies were delivered premature, 7% had birth asphyxia, 5% were born with low birth weight and stillbirth whereas only 1% had early neonatal death. The present study revealed that there was significant association between gestational age of delivery and Apgar score at 5 minutes and there was significant association between age and perinatal management outcome, gestational age of delivery and perinatal morbidity management, grading of proteinuria and perinatal morbidity management, grading of oedema and perinatal management outcome regarding neonatal outcome of pregnancy induced hypertension.Conclusion: Pregnancy induced hypertension during pregnancy were associated with a higher risk of adverse neonatal outcomes. Women with pregnancy induced hypertension during pregnancy had a higher risk of emergency caesarean section, pre-term birth, neonatal death, low birth weight children and neonates with low Apgar score. Maternal and fetal morbidity and mortality can be reduced by early recognition and institutional management.Birat Journal of Health SciencesVol.2/No.3/Issue 4/Sep- Dec 2017, Page: 255-259


2021 ◽  
Vol 10 (36) ◽  
pp. 3099-3102
Author(s):  
Mihir Kumar Sarkar ◽  
Arindam Halder

BACKGROUND Jaundice in pregnancy contributes to a significant proportion of maternal and perinatal morbidity and mortality in our country. Overall incidence in India is 1 - 4 per 1000 deliveries. There are increased risks of preterm labour, low birth weight babies, meconium-stained liquor, intrauterine fetal death and postpartum haemorrhage. The purpose of this study was to assess the fetomaternal outcome in pregnancy with jaundice in a tertiary level hospital. METHODS This was a two-year retrospective observational study conducted by reviewing the records of jaundice in pregnancy from April 2018 to March 2020. RESULTS Viral hepatitis comes out as the most common cause accounting for 70.37 % of the cases, whereas intrahepatic cholestasis with an incidence of 20. 37 % comes out as the second aetiology. Post-partum haemorrhage is depicted as the major maternal complication whereas prematurity and birth asphyxia come out as the major perinatal complications. CONCLUSIONS The present study projects viral hepatitis (Hepatitis A and E) as the major cause of jaundice in pregnancy. Although low maternal mortality has been recorded in the present study, a high perinatal mortality due to low birth weight and birth asphyxia remains to be a matter of major concern. KEY WORDS Jaundice in Pregnancy, Viral Hepatitis, Postpartum Haemorrhage, Prematurity, Birth Asphyxia


Author(s):  
Yi Wang ◽  
Lin Wang ◽  
Zeyong Yang ◽  
Fang Chen ◽  
Zhiwei Liu

Background: The prevalence of hypertensive disorder in pregnancy has been well-documented worldwide. In Chinese newborns, the risk of hypospadias in women with hypertension during pregnancy remains ambiguous. This study aimed to evaluate the relationship between hypertension in pregnancy and neonatal hypospadias based on a large sample of Chinese people. Methods: A retrospective cohort study was conducted at our hospital from 2015 to 2019. Mothers who delivered male infants with hypospadias or those without any malformations were enrolled. Factors such as hypertension, placenta previa, thyroid diseases, hepatitis B, obesity, multiple birth, amniotic fluid, gestational age, birth weight, and in vitro fertilization were collected to establish a regression analysis to assess risk factors for hypospadias. Results: In total, 41,490 mothers and 42,244 male infants were enrolled. The overall incidence of hypospadias was 0.23%. The occurrence rate of hypospadias in pregnancy-induced hypertension (PIH) group was higher than control group (0.944% vs. 0.186%, RR 5.08), whereas the occurrence rate in chronic hypertension group was 0%. Potential exposure factors were screened for hypospadias, and PIH, multiple birth, hyperthyroidism, preterm delivery, low birth weight, and small for gestational age (SGA) were found to have higher proportion of hypospadias in offspring. After adjustment for potential confounders in the multivariate regression analysis, PIH (OR: 2.437, 95% CI: 1.478–4.016, P<0.01), birth weight (OR: 0.852, 95% CI: 0.795–0.912, P<0.01), and SGA (OR: 3.282, 95% CI: 1.644–6.549, P<0.01) showed a significant relationship with hypospadias. Conclusion: Women with PIH had higher risks of hypospadias in offspring. Lower birth weight, SGA and hyperthyroidism were also statistically associated with hypospadias.


2020 ◽  
Vol 28 (1) ◽  
pp. 94-99 ◽  
Author(s):  
Rashida Khanom ◽  
Jamsed Faridi ◽  
Jinnatun Nur ◽  
Sumaiya Akter ◽  
Kamalesh Chandra Basu

Purpose: Preeclampsia and eclampsia is one of the leading causes of maternal and fetal morbidity and mortality worldwide. Visual disturbances in (pre)eclampsia seem to be frequent phenomena. Therefore, the obstetrician/gynecologist may encounter women with serious, and sometimes debilitating, pathology of the visual pathways. Methods: This is a cross sectional observational study was conducted over a period of 12 months (January 2016-December 2016) at Dhaka Medical College Hospital, Dhaka, Bangladesh. Patients with severe preeclampsia and eclampsia were included in the study. The association was measured with Chi-squared test and p value of 0.05 was treated as significant. Results: During this 12-month period, 100 patients with severe preeclampsia and eclampsia were studied the mean age was 26.4 ± 5.5 years. The association between retinal changes and different variables was statistically significant positive association between the presence of retinal changes and blood pressure (P= 0.0118), proteinuria (P= 0.0025). However, age (P= 0.7123), and gravida (P= 0.7998) were not associated with occurrence of retinopathy in our study. The most common retinal change was noted and narrowing of arterioles, (83%) that retinal changes were significantly more in patients with severe hypertension, exudate (12%) and haemorrhages (10%) observed in present study. The presence of macular edema (5%) and retinal detachment (2%) are the warning signs for termination of pregnancy to save the vision of the mother. Conclusion: It is called that eye is the gateway of medicine, so in pregnancy induced hypertension presence of changes in the retinal arterioles and retinal haemorrhages may indicate similar changes in the placenta. Since the well-being of the foetus depends on the placental circulation, ophthalmoscopic examination of mother’s fundus may give a clue to similar micro-circulation changes in the placenta and indirectly to the foetal wellbeing. J Dhaka Medical College, Vol. 28, No.1, April, 2019, Page 94-99


2015 ◽  
Vol 4 (3) ◽  
pp. 205 ◽  
Author(s):  
Shikha Saxena ◽  
KV Thimmaraju ◽  
PremC Srivastava ◽  
AyazK Mallick ◽  
Biswajit Das ◽  
...  

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