Total Hip Arthroplasty in Very Young Bone Marrow Transplant Patients

2015 ◽  
Vol 24 (02) ◽  
Author(s):  
Cameron K. Ledford ◽  
Alexander R. Vap ◽  
Michael P. Bolognesi ◽  
Samuel S. Wellman
Keyword(s):  
Bone Marrow ◽  
Total Hip Arthroplasty ◽  
Bone Marrow Transplant ◽  
Hip Arthroplasty ◽  
Marrow Transplant ◽  
Total Hip ◽  
Transplant Patients

scholarly journals Total Hip Arthroplasty in Very Young Bone Marrow Transplant Patients

2014 ◽  
Vol 4 (1) ◽  
pp. 19-23
Author(s):  
Samuel S Wellman ◽  
Cameron Ledford ◽  
Alexander R Vap
Keyword(s):  
Bone Marrow ◽  
Total Hip Arthroplasty ◽  
Bone Marrow Transplant ◽  
Hip Arthroplasty ◽  
Young Patients ◽  
Marrow Transplant ◽  
Allogeneic Bone ◽  
Total Hip ◽  
Transplant Patients

ABSTRACT Concerns remain about total hip arthroplasty (THA) performed in very young patients, especially those with complex medical history such as allogeneic bone marrow transplantation (ABMT). This study retrospectively reviews the perioperative courses and functional outcomes of ABMT patients <21 years old undergoing primary uncemented THA. Nine THAs were performed in five ABMT patients at an average age of 19.7 years. The interval between ABMT and THA was 73.0 months with clinical follow-up of 25.8 months. Harris Hip Scores (HHS) increased dramatically from preoperatively 44.5 (31.1-53.4) to postoperatively 85.2 (72.0-96.0) and all patients subjectively reported a good (4 hips) to excellent (5 hips) overall outcome. There was one reoperation for periprosthetic fracture fixation but there were no infections or revisions performed. Despite the history of severe hematopoietic conditions requiring ABMT, these very young patients do appear to have improved pain and function following primary THA with short-term follow-up. These results are comparable to prior studies of adult ABMT patients undergoing THA and are encouraging given the complexity of the decision to perform hip arthroplasty in the medically complicated very young patient. Ledford CK, Vap AR, Bolognesi MP, Wellman SS. Total Hip Arthroplasty in Very Young Bone Marrow Transplant Patients. The Duke Orthop J 2014;4(1):19-23.

Monitoring Cardiotoxicity in Bone Marrow Transplant Patients With Prior Anthracycline (AC) Therapy

2021 ◽  
Vol 30 ◽  
pp. S198-S199
Author(s):  
P. Emerson ◽  
S. Mahendran ◽  
L. Stefani ◽  
T. Deshmukh ◽  
S. Trivedi ◽  
...  
Keyword(s):  
Bone Marrow ◽  
Bone Marrow Transplant ◽  
Marrow Transplant ◽  
Transplant Patients

scholarly journals Detection of Human Polyomaviruses in Urine from Bone Marrow Transplant Patients: Comparison of Electron Microscopy with PCR

2004 ◽  
Vol 50 (2) ◽  
pp. 306-312 ◽  
Author(s):  
Stefan S Biel ◽  
Andreas Nitsche ◽  
Andreas Kurth ◽  
Wolfgang Siegert ◽  
Muhsin Özel ◽  
...  
Keyword(s):  
Electron Microscopy ◽  
Bone Marrow ◽  
Real Time ◽  
Bone Marrow Transplant ◽  
Real Time Pcr ◽  
Marrow Transplant ◽  
Test System ◽  
Urine Samples ◽  
Clinical Samples ◽  
Transplant Patients

Abstract Background: We studied electron microscopy (EM) as an appropriate test system for the detection of polyomavirus in urine samples from bone marrow transplant patients. Methods: We evaluated direct EM, ultracentrifugation (UC) before EM, and solid-phase immuno-EM (SPIEM). The diagnostic accuracy of EM was studied by comparison with a real-time PCR assay on 531 clinical samples. Results: The detection rate of EM was increased by UC and SPIEM. On 531 clinical urine samples, the diagnostic sensitivity of EM was 47% (70 of 149) with a specificity of 100%. We observed a linear relationship between viral genome concentration and the proportion of urine samples positive by EM, with a 50% probability for a positive EM result for urine samples with a polyomavirus concentration of 106 genome-equivalents (GE)/mL; the probability of a positive EM result was 0% for urine samples with &lt;103 GE/mL and 100% for urine samples containing 109 GE/mL. Conclusions: UC/EM is rapid and highly specific for polyomavirus in urine. Unlike real-time PCR, EM has low sensitivity and cannot quantify the viral load.

scholarly journals Infectious Complications in Bone Marrow Transplant Patients

BMJ ◽  
1971 ◽  
Vol 1 (5739) ◽  
pp. 18-23 ◽  
Author(s):  
C. O. Solberg ◽  
H. J. Meuwissen ◽  
R. N. Needham ◽  
R. A. Good ◽  
J. M. Matsen
Keyword(s):  
Bone Marrow ◽  
Bone Marrow Transplant ◽  
Marrow Transplant ◽  
Infectious Complications ◽  
Transplant Patients

Efficacy of Amlodipine in Pediatric Bone Marrow Transplant Patients

1998 ◽  
Vol 37 (1) ◽  
pp. 31-35 ◽  
Author(s):  
Sohail Khattak ◽  
John W. Rogan ◽  
E. Fred Saunders ◽  
Jochen G. W. Theis ◽  
Gerald S. Arbus ◽  
...  
Keyword(s):  
Bone Marrow ◽  
Bone Marrow Transplant ◽  
Marrow Transplant ◽  
Transplant Patients

Pathology of the pancreas in bone marrow transplant patients

1993 ◽  
Vol 24 (2) ◽  
pp. 152-159
Author(s):  
Kay Washington ◽  
William Peters ◽  
Marcia R. Gottfried
Keyword(s):  
Bone Marrow ◽  
Bone Marrow Transplant ◽  
Marrow Transplant ◽  
Transplant Patients

Avascular necrosis of bone in bone marrow transplant patients

1989 ◽  
Vol 17 (2) ◽  
pp. 140-143 ◽  
Author(s):  
J. A. Russell ◽  
W. B. Blahey ◽  
T. A. Stuart ◽  
G. Edwards ◽  
R. T. Card
Keyword(s):  
Bone Marrow ◽  
Bone Marrow Transplant ◽  
Avascular Necrosis ◽  
Marrow Transplant ◽  
Transplant Patients ◽  
Avascular Necrosis Of Bone
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