Lack of Effect of Short-term Lisinopril Administration on Left Ventricular Filling Dynamics in Hypertensive Patients with Diastolic Dysfunction

1997 ◽  
Vol 6 (5) ◽  
pp. 307-312 ◽  
Author(s):  
C. Cuspidi ◽  
L. Lonati ◽  
L. Sampieri ◽  
G. Leonetti ◽  
M. L. Muiesan ◽  
...  
Keyword(s):  
Diastolic Dysfunction ◽  
Left Ventricular ◽  
Left Ventricular Filling ◽  
Short Term ◽  
Hypertensive Patients ◽  
Ventricular Filling

Left Ventricular Filling Profiles in Young White-Coat Hypertensive Patients Without Hypertrophy

Hypertension ◽  
1997 ◽  
Vol 30 (3) ◽  
pp. 746-752 ◽  
Author(s):  
Nen-Chung Chang ◽  
Zhi-Yang Lai ◽  
Paul Chan ◽  
Tze-Che Wang
Keyword(s):  
Left Ventricular ◽  
Left Ventricular Filling ◽  
White Coat ◽  
Hypertensive Patients ◽  
Ventricular Filling

Impaired left ventricular filling in borderline hypertensive patients without cardiac structural changes

1993 ◽  
Vol 125 (6) ◽  
pp. 1710-1716 ◽  
Author(s):  
Gaston Kakota Kapuku ◽  
Shinji Seto ◽  
Hideki Mori ◽  
Mitsuhiro Mori ◽  
Toshinori Utsunomia ◽  
...  
Keyword(s):  
Structural Changes ◽  
Left Ventricular ◽  
Left Ventricular Filling ◽  
Hypertensive Patients ◽  
Ventricular Filling

Left ventricular filling pattern in hypertensive patients after reversal of myocardial hypertrophy

1987 ◽  
Vol 17 (2) ◽  
pp. 177-185 ◽  
Author(s):  
Luciano Agati ◽  
Francesco Fedele ◽  
Maria Penco ◽  
Susanna Sciomer ◽  
Armando Dagianti
Keyword(s):  
Myocardial Hypertrophy ◽  
Left Ventricular ◽  
Left Ventricular Filling ◽  
Hypertensive Patients ◽  
Filling Pattern ◽  
Ventricular Filling

Interpretation and implication of diastolic dysfunction in critically ill patients

2017 ◽  
Author(s):  
Claire Colebourn ◽  
Jim Newton
Keyword(s):  
Diastolic Dysfunction ◽  
Diastolic Function ◽  
Critically Ill ◽  
Critically Ill Patients ◽  
Left Ventricular ◽  
Left Ventricular Filling ◽  
Critically Ill Patient ◽  
Severe Illness ◽  
Ventricular Relaxation ◽  
Ventricular Filling

This chapter looks at the interpretation of parameters of diastolic function in the critically ill patient. It provides a guide to interpretation and how to avoid misinterpretation of these parameters in the context of severe illness. The assessment of left ventricular relaxation and left ventricular filling pressures are described in detail.

scholarly journals Mechanistic validation of the 2016 American Society of Echocardiography/European Association of Cardiovascular Imaging Guidelines for the assessment of diastolic dysfunction in heart failure with reduced ejection fraction

2020 ◽  
Vol 18 (1) ◽  
Author(s):  
Ythan H. Goldberg ◽  
David Megyessi ◽  
Mischa Flam ◽  
Daniel M. Spevack ◽  
Martin G. Sundqvist ◽  
...  
Keyword(s):  
Ejection Fraction ◽  
Diastolic Dysfunction ◽  
European Association ◽  
Cardiovascular Imaging ◽  
Left Ventricular ◽  
Left Ventricular Filling ◽  
Mechanistic Insight ◽  
American Society ◽  
Ventricular Filling ◽  
Insight Into

Abstract Background The American Society for Echocardiography/European Association of Cardiovascular Imaging (ASE/EACVI) 2016 guidelines for assessment of diastolic dysfunction (DD) are based primarily on the effects of diastolic dysfunction on left ventricular filling hemodynamics. However, these measures do not provide quantifiable mechanistic information about diastolic function. The Parameterized Diastolic Filling (PDF) formalism is a validated theoretical framework that describes DD in terms of the physical properties of left ventricular filling. Aims We hypothesized that PDF analysis can provide mechanistic insight into the mechanical properties governing higher grade DD. Methods Patients referred for echocardiography showing reduced left ventricular ejection fraction (< 45%) were prospectively classified into DD grade according to 2016 ASE/EACVI guidelines. Serial E-waves acquired during free breathing using pulsed wave Doppler of transmitral blood flow were analyzed using the PDF formalism. Results Higher DD grade (grade 2 or 3, n = 20 vs grade 1, n = 30) was associated with increased chamber stiffness (261 ± 71 vs 169 ± 61 g/s2, p < 0.001), increased filling energy (2.0 ± 0.9 vs 1.0 ± 0.5 mJ, p < 0.001) and greater peak forces resisting filling (median [interquartile range], 18 [15–24] vs 11 [8–14] mN, p < 0.001). DD grade was unrelated to chamber viscoelasticity (21 ± 4 vs 20 ± 6 g/s, p = 0.32). Stiffness was inversely correlated with ejection fraction (r = − 0.39, p = 0.005). Conclusions Higher grade DD was associated with changes in the mechanical properties that determine the physics of poorer left ventricular filling. These findings provide mechanistic insight into, and independent validation of the appropriateness of the 2016 guidelines for assessment of DD.

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