scholarly journals Severe acute respiratory infection and viral infections in adult patients: active surveillance results

2019 ◽  
Vol 2 (3) ◽  
Keyword(s):  
Active Surveillance ◽  
Respiratory Infection ◽  
Acute Respiratory Infection ◽  
Viral Infections ◽  
Adult Patients ◽  
Severe Acute Respiratory Infection

scholarly journals Etiological and epidemiological characteristics of severe acute respiratory infection caused by multiple viruses and Mycoplasma pneumoniae in adult patients in Jinshan, Shanghai: A pilot hospital-based surveillance study

PLoS ONE ◽  
2021 ◽  
Vol 16 (3) ◽  
pp. e0248750 ◽  
Author(s):  
Jian Li ◽  
Can-Lei Song ◽  
Tang Wang ◽  
Yu-Long Ye ◽  
Jian-Ru Du ◽  
...  
Keyword(s):  
Influenza Virus ◽  
Mycoplasma Pneumoniae ◽  
Active Surveillance ◽  
Respiratory Infection ◽  
Acute Respiratory Infection ◽  
Adult Patients ◽  
Chronic Medical Condition ◽  
Human Bocavirus ◽  
Influenza Virus A ◽  
Severe Acute Respiratory Infection

Background Severe acute respiratory infection (SARI) results in a tremendous disease burden worldwide. Available research on active surveillance among hospitalized adult patients suffering from SARI in China is limited. This pilot study aimed to identify associated etiologies and describe the demographic, epidemiological and clinical profiles of hospitalized SARI patients aged over 16 years in Jinshan, Shanghai. Methods Active surveillance was conducted at 1 sentinel hospital in Jinshan district, Shanghai, from April 2017 to March 2018. Hospitalized SARI patients aged over 16 years old were enrolled, and nasopharyngeal swabs were collected within 24 hours of admission and tested for multiple respiratory viruses (including 18 common viruses) and Mycoplasma pneumoniae with real-time polymerase chain reaction. Demographic, epidemiological and clinical information was obtained from case report forms. Results In total, 397 SARI patients were enrolled; the median age was 68 years, and 194 (48.9%) patients were male. A total of 278 (70.0%) patients had at least one underlying chronic medical condition. The most frequent symptoms were cough (99.2%) and sputum production (88.4%). The median duration of hospitalization was 10 days. A total of 250 infection patients (63.0%) were positive for at least one pathogen, of whom 198 (49.9%) were positive for a single pathogen and 52 (13.1%) were positive for multiple pathogens. The pathogens identified most frequently were M. pneumoniae (23.9%, 95/397), followed by adenovirus (AdV) (11.6%, 46/397), influenza virus A/H3N2 (Flu A/H3N2) (11.1%, 44/397), human rhinovirus (HRhV) (8.1%, 32/397), influenza virus B/Yamagata (Flu B/Yamagata) (6.3%, 25/397), pandemic influenza virus A/H1N1 (Flu A/pH1N1) (4.0%, 16/397), parainfluenza virus (PIV) type 1 (2.0%, 8/397), human coronavirus (HCoV) type NL63 (2.0%, 8/397), HCoV 229E (1.5%, 6/397), HCoV HKU1 (1.5%, 6/397), PIV 3 (1.5%, 6/397), human metapneumovirus (HMPV) (1.5%, 6/397), PIV 4 (1.3%, 5/397), HCoV OC43 (1.0%, 4/397), influenza virus B/Victoria (Flu B/Victoria) (0.5%, 2/397), respiratory syncytial virus (RSV) type B (0.5%, 2/397), and human bocavirus (HBoV) (0.3%, 1/397). The seasonality of pathogen-confirmed SARI patients had a bimodal distribution, with the first peak in the summer and the second peak in the winter. Statistically significant differences were observed with respect to the rates of dyspnea, radiographically diagnosed pneumonia and the presence of at least one comorbidity in patients who were infected with only M. pneumoniae, AdV, HRhV, Flu A/H3N2, Flu A /pH1N1 or Flu B/Yamagata. The differences in the positivity rates of the above 6 pathogens among the different age groups were nonsignificant. Conclusions M. pneumoniae, AdV and Flu A/H3N2 were the main pathogens detected in hospitalized SARI patients aged over 16 years old in Jinshan district, Shanghai. Our findings highlight the importance of sustained multipathogen surveillance among SARI patients in sentinel hospitals, which can provide useful information on SARI etiologies, epidemiology, and clinical characteristics.

scholarly journals Host characteristics predict outcome among adult patients admitted by severe acute respiratory infection

2019 ◽  
Vol 147 (7) ◽  
pp. 842-851
Author(s):  
Alberto Fica ◽  
Francisco Pinto ◽  
Viviana Sotomayor ◽  
Rodrigo Fasce ◽  
Winston Andrade ◽  
...  
Keyword(s):  
Respiratory Infection ◽  
Acute Respiratory Infection ◽  
Adult Patients ◽  
Severe Acute Respiratory Infection ◽  
Host Characteristics

scholarly journals The Viral Etiologies of Severe Acute Respiratory Infection: Indian Perspective on the Emerging Pathogens

2020 ◽  
Vol 14 (4) ◽  
pp. 2277-2285
Author(s):  
Tushar Shaw ◽  
V.A. Indumathi
Keyword(s):  
Respiratory Infection ◽  
Acute Respiratory Infection ◽  
Viral Infections ◽  
Virus Disease ◽  
Emerging Pathogens ◽  
Public Health Importance ◽  
Severe Acute Respiratory Infection ◽  
Cultural Ecological ◽  
Viral Etiologies ◽  
Indian Perspective

Severe Acute Respiratory Infection poses a significant threat to human health being a major cause of morbidity and mortality. India has witnessed several outbreaks of different infectious etiologies in the past. Among these, several new viral infections have been classified as emerging threat to humans. The word emerging refers to infectious etiologies that have newly appeared in the community or are rapidly increasing their range, corresponding to upsurge in the number of cases. Several different elements can contribute to the emergence of a new virus disease that may cause epidemic or pandemic around the globe. Containment of these viruses is difficult as most of them are of zoonotic origin. There is no immunity in the community against these viruses leaving individuals vulnerable to the disease. Factors such as socio-cultural, ecological along with human animal interphase creates challenges with respect to the emergence of these viral diseases. The major emerging viral infections of public health importance with respect to severe acute respiratory infection in India has been reviewed in this article.

scholarly journals Etiologies of severe acute respiratory infection (SARI) and misdiagnosis of influenza in Indonesia, 2013‐2016

2020 ◽  
Vol 15 (1) ◽  
pp. 34-44
Author(s):  
Abu Tholib Aman ◽  
Tri Wibawa ◽  
Herman Kosasih ◽  
Rizka Humardewayanti Asdie ◽  
Ida Safitri ◽  
...  
Keyword(s):  
Respiratory Infection ◽  
Acute Respiratory Infection ◽  
Severe Acute Respiratory Infection
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