scholarly journals One structure, multiple features: The phycocyanin in biotechnology

2020 ◽  
pp. 28-42
Author(s):  
Imene CHENTIR ◽  
Moncef NASRI
Keyword(s):  
Structural Characteristics ◽  
Review Article ◽  
Fluorescent Labeling ◽  
Water Soluble ◽  
Important Research ◽  
Biotechnological Applications ◽  
Multiple Features ◽  
Nanopar Ticles ◽  
Extraction And Purification ◽  
Research Findings

Phycocyanine (PC) is a water-soluble, non-toxic and bioactive (antioxidant, anti-inflammatory, antitumor, etc.) phycobiliprotein isolated, mainly, from cyanobacteria. Due to its several properties, PC is considered to be a rising biomolecule for Industrial exploitation, and has become an important research axis in order to promote its production, and optimize its biotechnological applications. The aim of this review article was to discuss the basic, and recent properties and applications of PC, and to bring together data on various aspects of PC stabilization, and PC nanopar-ticles formulation. In addition, an overview of the main structural characteristics and process-ses of PC extraction and purification were also discussed. The recent scientific research findings concluded that PC is a promising both functional, and bioactive additive in industry, especially, in food as a dye, in imaging as a fluorescent labeling agent, and in the phar-maceutical and nano-pharmaceutical field as a bioactive molecule and nanopar-ticles, particularly, due to it antitumor capacity. Phycocyanine is, thus, a promising bio-active molecules in pharmacological, and medical fields.

Organocatalytic dimensions to the C–H functionalization of the carbocyclic core in indoles: a review update

2021 ◽  
Author(s):  
Prantika Bhattacharjee ◽  
Utpal Bora
Keyword(s):  
Important Research ◽  
Research Findings

A review highlighting important research findings in remote C–H activation processes using effectual organocatalytic perspectives. The challenging indole carbocyclic ring positions were successfully accessed with proper regio- and stereocontrols.

scholarly journals RESEARCH OF EFFECT OF DPEI-PROCESSING OF SHIITAKE FRUIT BODY ON PHYSICAL AND MECHANICAL PROPERTIES OF MUSHROOM SUSPENSION

2018 ◽  
Vol 41 (1) ◽  
pp. 27-33
Author(s):  
N.O. Sharkova ◽  
E.К. Zhukotskyi ◽  
Т.Y. Тurchyna ◽  
H.V. Dekusha ◽  
A.A. Makarenko
Keyword(s):  
Mechanical Properties ◽  
Dynamic Viscosity ◽  
Structural Characteristics ◽  
Specific Energy Consumption ◽  
Fruit Body ◽  
Heterogeneous Systems ◽  
Physical And Mechanical Properties ◽  
Water Soluble ◽  
Shiitake Mushroom ◽  
Working Bodies

The use of discrete-pulse energy input (DPEI) mechanisms in various industries has become a reliable tool for the intensification of heat and mass transfer processes in various technological lines and reduction of specific energy consumption. The study of structural transformations in heterogeneous systems under influence of mechanisms of DPEI opens up new possibilities for their use as evidenced by this article. Under certain conditions it is possible to prepare a mushroom suspension with specified characteristics for drying and enhance medicinal properties of the obtained powder product while retaining all valuable components of feedstock. The article presents the results of research of DPEI-processing effect of the shiitake mushroom fruit body on the on physical and mechanical properties and structural characteristics of the mushroom suspension. The influence of hydro module, temperature of the suspension and the layout of the working bodies of the rotor-pulse apparatus (RPA) on its dynamic viscosity was studied and the possibility of reducing viscosity by 2-3 times is shown.  An analysis of mushroom suspension microstructure has showed that with a certain layout of the working bodies of the RPA it is possible to control the degree of dispersion of particles and change the spatial structure of the aggregates in the volume of the dispersion medium. It is determined that self-organization of spatial aggregates from individual hyphae in such suspensions occurs over time. Moreover, the smaller the size of hyphae (≤ 25 microns after the RPA of the first version of the arrangement: rotor-stator-rotor) are, the larger the size of the spatial aggregates are formed. After the RPA with the second layout option, the fragments of hyphae had sizes ≥ 50 μm, but the dimensions of the spatial aggregates were three times smaller. It is found that after three times passing of the mushroom suspension through the RPA and its subsequent treatment in the cavitation device, the dynamic viscosity of the suspension is reduced by 20%. Confirmation of the the effectiveness of the DPEI-mechanisms in obtaining mushroom suspension is that due to the hydromechanical destruction of the polysaccharide structures of the chitin-glucan complex of the shiitake mushroom the content of the bioavailable complex of water-soluble oncostatic and immunoregulatory polysaccharides in the powder obtained by drying the mushroom suspension in an experimental spray dryer increased 6 times. References 13, figures 6.

scholarly journals Novel Antioxidant and Hypoglycemic Water-Soluble Polysaccharides from Jasmine Tea

Foods ◽  
2021 ◽  
Vol 10 (10) ◽  
pp. 2375
Author(s):  
Yayuan Tang ◽  
Jinfeng Sheng ◽  
Xuemei He ◽  
Jian Sun ◽  
Zhen Wei ◽  
...  
Keyword(s):  
Galacturonic Acid ◽  
High Performance ◽  
Structural Characteristics ◽  
Gel Permeation Chromatography ◽  
Helical Structure ◽  
Water Soluble ◽  
Nuclear Magnetic Resonance Analysis ◽  
Molar Ratios ◽  
Jasmine Tea

There have been few studies dealing with chemical elucidation and pharmacological potentials of water-soluble polysaccharides from jasmine tea, limiting their use in functional foods. In this study, water-soluble polysaccharides (named as JSP) were extracted from Jasminum sambac (L.) Aiton tea and fractionated to afford two sub-fractions (JSP-1 and JSP-2). The main structural characteristics of novel JSP sub-fractions were determined by high performance gel permeation chromatography, ultra-performance liquid chromatography-tandem mass spectrometry, Fourier transform infrared, and nuclear magnetic resonance analysis. Physiologically, the abilities of JSP-1 and JSP-2 to reduce ferric ions, scavenge DPPH and hydroxyl radicals, as well as protect islet cells were confirmed in vitro. JSP-1 exhibited better antioxidant and hypoglycemic activities than JSP-2. The molecular weights of JSP-1 and JSP-2 were 18.4 kDa and 14.1 kDa, respectively. JSP-1 was made up of glucose, galactose, rhamnose, xylose, arabinose, and galacturonic acid with molar ratios 1.14:4.69:1.00:9.92:13.79:4.09, whereas JSP-2 with a triple helical structure was composed of galactose, rhamnose, xylose, arabinose, and galacturonic acid as 3.80:1.00:8.27:11.85:5.05 of molar ratios. JSP-1 contains →1)-α-Galƒ-(3→, →1)-α-Galƒ-(2→, →1)-α-Araƒ-(5→, →1)-α-Araƒ-(3→, →1)-α-Araƒ-(3,5→, →1)-β-Xylp-(2→ and →1)-β-Xylp-(3→ residues in the backbone. These results open up new pharmacological prospects for the water-soluble polysaccharides extracted from jasmine tea.

scholarly journals Immigrants in polish economy

VUZF Review ◽  
2021 ◽  
Vol 6 (2) ◽  
pp. 233-238
Author(s):  
Iwona Dudzik ◽  
Irena Brukwicka
Keyword(s):  
Immigrant Workers ◽  
Physical Work ◽  
Important Research ◽  
Intention To Stay ◽  
The Past ◽  
Industrial Sectors ◽  
Research Findings ◽  
The Republic ◽  
Polish Economy ◽  
Near Future

This article deals with immigrants in Polish economy. The aim of the article is to present the most important research findings, concerning immigrants and enterprises where they are employed. This issue also includes the influence of the COVID-19 pandemic. The authors of this paper focused mostly on Ukrainian immigrants. It has been proven that increase in the number of immigrant workers leads to the growth of the Gross Domestic Product, and contributes to the faster growth in remittances from the Republic of Poland to Ukraine. As a result of the adverse impact of the COVID-19 pandemic on sales, non-employment costs were reduced in the service and industrial sectors. Employment changes were not correlated with company’s situation.  It is worth noting, that because of the COVID-19 pandemic, some companies may be less inclined to recruit immigrants in the near future, and the overall demand for labor may decrease. This is particularly important, because the primary reason for employment people from abroad was the inability to meet labor needs of the citizens of Poland. The majority of immigrants are employed only to perform physical work which does not require qualifications. Large companies show greater interest in the foreign human capital. Over the past five years, there has been an increase in the number of immigrants who declared their intention to stay in Poland for a longer period of time. More than half of the immigrants stay in Poland, with at least, one family member. On this basis, it may be concluded that the number of immigrants willing to settle in Poland is growing.

Experimental Pragmatics

2015 ◽  
Author(s):  
Raymond W. Gibbs
Keyword(s):  
Common Ground ◽  
Experimental Methods ◽  
Alternative View ◽  
Important Research ◽  
Experimental Pragmatics ◽  
Linguistic Pragmatics ◽  
Conversational Implicatures ◽  
Research Findings ◽  
Discourse Understanding

This chapter describes some of the important research in experimental pragmatics, most notably studies related to recovering speakers’ intentions, inferring conversational implicatures, and the role of common ground in discourse understanding. My aim is to demonstrate the utility of different experimental methods for studying pragmatics, and how research findings in the field are relevant to traditional concerns within the linguistic pragmatics community. But I will also argue that experimental pragmatic studies show great regularities and significant variation, both within and across individuals, in the ways people speak and understand language. My alternative view claims that dynamical, self-organizing processes form the critical background from which meaningful pragmatic actions emerge. The implications of this position for interdisciplinary pragmatic research will be discussed.

scholarly journals Kidney manifestations of diabetes mellitus – A Review

2018 ◽  
Vol 9 (4) ◽  
pp. 126
Author(s):  
Swaminathan S. ◽  
Rajeswari S. ◽  
Wasim Mohideen
Keyword(s):  
Diabetes Mellitus ◽  
Insulin Resistance ◽  
Kidney Disease ◽  
Delayed Diagnosis ◽  
Review Article ◽  
Metabolic Disturbances ◽  
Research Findings ◽  
Sedentary Life ◽  
Sedentary Life Style ◽  
Prevalence Of Diabetes Mellitus

    The prevalence of diabetes mellitus, especially T2DM is on the increase worldwide and in a developing country like india, as of date approximately 30 – 40% of population are identified as having DM. Sedentary life style, obesity, increased BMI, insulin resistance, hyperlipidemia, delayed diagnosis and metabolic syndrome are some of the factors  that lead to the development of DM. Extensive research have been conducted in this field and still more studies are being undertaken. The first organ affected in all uncontrolled DM patients is the kidney, followed by liver and cardiac. Kidney disease predominantly account for increased mortality among T2DM and is the main cause of CKD as well as DN. Treatment of CKD  due to  uncontrolled T2DM is still controversial because of the scarcity of evidence available. MA plays a significant role in screening pre and established DM.  Increased levels of urate is identified as one of the metabolic disturbances in T2DM. This review article summaries the research findings during the last two decades on the manifestations of kidney disease in T2DM.

scholarly journals RECENT APPROACHES OF SOLID DISPERSION: A NEW CONCEPT TOWARD ORAL BIOAVAILABILITY SABITRI BINDHANI* , SNEHAMAYEE MOHAPATRA

2018 ◽  
Vol 11 (2) ◽  
pp. 72 ◽  
Author(s):  
Sabitri Bindhani ◽  
Snehamayee Mohapatra
Keyword(s):  
Solid Dispersion ◽  
Relative Bioavailability ◽  
Review Article ◽  
Water Soluble ◽  
Advanced Technology ◽  
Minimum Level ◽  
Bioavailability Enhancement ◽  
The Past ◽  
Poorly Soluble

 Solid dispersion (SD) has been a major advanced technology in overcoming dissolution and bioavailability problem of poorly soluble compounds. Formulation of SD in water-soluble carrier has becoming more researched over the past four decades for solubility and relative bioavailability enhancement. By reduction of the size of the drug particle to the minimum level which will enhance drug wettability and ultimately bioavailability will be definitely improved. This review article elaborates recent advanced technology and characterization of SDs and also discusses the problems and their solution for the development of better formulations.

scholarly journals Latency and Cybersickness: Impact, Causes, and Measures. A Review

2020 ◽  
Vol 1 ◽  
Author(s):  
Jan-Philipp Stauffert ◽  
Florian Niebling ◽  
Marc Erich Latoschik
Keyword(s):  
Review Article ◽  
Measurement Methods ◽  
Low Latency ◽  
Interactive Graphics ◽  
Counter Measures ◽  
Systems Research ◽  
Sound Experiment ◽  
Measurement Results ◽  
Research Findings ◽  
Good Measurement

Latency is a key characteristic inherent to any computer system. Motion-to-Photon (MTP) latency describes the time between the movement of a tracked object and its corresponding movement rendered and depicted by computer-generated images on a graphical output screen. High MTP latency can cause a loss of performance in interactive graphics applications and, even worse, can provoke cybersickness in Virtual Reality (VR) applications. Here, cybersickness can degrade VR experiences or may render the experiences completely unusable. It can confound research findings of an otherwise sound experiment. Latency as a contributing factor to cybersickness needs to be properly understood. Its effects need to be analyzed, its sources need to be identified, good measurement methods need to be developed, and proper counter measures need to be developed in order to reduce potentially harmful impacts of latency on the usability and safety of VR systems. Research shows that latency can exhibit intricate timing patterns with various spiking and periodic behavior. These timing behaviors may vary, yet most are found to provoke cybersickness. Overall, latency can differ drastically between different systems interfering with generalization of measurement results. This review article describes the causes and effects of latency with regard to cybersickness. We report on different existing approaches to measure and report latency. Hence, the article provides readers with the knowledge to understand and report latency for their own applications, evaluations, and experiments. It should also help to measure, identify, and finally control and counteract latency and hence gain confidence into the soundness of empirical data collected by VR exposures. Low latency increases the usability and safety of VR systems.

scholarly journals Chondroitin Sulfate Safety and Quality

Molecules ◽  
2019 ◽  
Vol 24 (8) ◽  
pp. 1447 ◽  
Author(s):  
Nicola Volpi
Keyword(s):  
Chondroitin Sulfate ◽  
High Performance ◽  
Oral Absorption ◽  
Structural Characteristics ◽  
Biological Effects ◽  
Marine Species ◽  
Raw Material ◽  
Size Exclusion ◽  
Heterogeneous Structure ◽  
Extraction And Purification

The industrial production of chondroitin sulfate (CS) uses animal tissue sources as raw material derived from different terrestrial or marine species of animals. CS possesses a heterogeneous structure and physical-chemical profile in different species and tissues, responsible for the various and more specialized functions of these macromolecules. Moreover, mixes of different animal tissues and sources are possible, producing a CS final product having varied characteristics and not well identified profile, influencing oral absorption and activity. Finally, different extraction and purification processes may introduce further modifications of the CS structural characteristics and properties and may lead to extracts having a variable grade of purity, limited biological effects, presence of contaminants causing problems of safety and reproducibility along with not surely identified origin. These aspects pose a serious problem for the final consumers of the pharmaceutical or nutraceutical products mainly related to the traceability of CS and to the declaration of the real origin of the active ingredient and its content. In this review, specific, sensitive and validated analytical quality controls such as electrophoresis, eHPLC (enzymatic HPLC) and HPSEC (high-performance size-exclusion chromatography) able to assure CS quality and origin are illustrated and discussed.

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