Physico-chemical Characteristics of Amino Acids in Aqueous Solution of Amikacin Sulphate

2021 ◽  
Author(s):  
Poonam Chaudhary ◽  
◽  
Suvarcha Chauhan ◽  
Vivek Sharma ◽  
Kuldeep Singh ◽  
...  
Keyword(s):  
Aqueous Solution ◽  
Amino Acids ◽  
Chemical Characteristics ◽  
Physico Chemical

scholarly journals STANDARD ENTHALPY OF FORMATION OF PARAOXYPHENYLGLYCINE AND PRODUCTS OF ITS DISSOCIATION IN AQUEOUS SOLUTION

2019 ◽  
Vol 62 (8) ◽  
pp. 81-86
Author(s):  
Aleksandr I. Lytkin ◽  
Viktor V. Chernikov ◽  
Olga N. Krutova ◽  
Svetlana A. Bychkova ◽  
Pavel D. Krutov
Keyword(s):  
Aqueous Solution ◽  
Amino Acids ◽  
Chemical Nature ◽  
Thermodynamic Characteristics ◽  
Potassium Nitrate ◽  
Enthalpies Of Formation ◽  
Standard Enthalpy Of Formation ◽  
Enthalpy Of Dissolution ◽  
Time Curve ◽  
Physico Chemical

Depending on the chemical nature of the side radicals, amino acids can be divided into aromatic and aliphatic, as well as amino acids, the presence of non-polar or polar functional groups in the side radicals. Since the characteristics of individual amino acids in the protein are determined by the nature (physico-chemical properties) of their side radicals, which are in a hydrated state. It is also extremely important to study the thermodynamic characteristics of the hydration of the side radicals of amino acids of different chemical nature. To obtain empirical correlations that would establish a connection between the thermodynamic parameters of the interaction of dissolved compounds with the solvent and the size of the molecules to be dissolved (having different physico-chemical nature), it is necessary to accumulate a sufficient amount of experimental data on the heats of dissolution of amino acids. This will allow you to calculate the contribution of intermolecular interactions for different groups of molecules. By potentiometric method the protolytic equilibria in aqueous solutions of paraoxyphenylglycine were investigated. The measurements were carried out at a temperature of 298.15 K and an ionic strength of 0.25 (against the background of potassium nitrate). Calorimetric measurements were carried out on an ampoule calorimeter, with an isothermal shell, a thermistor temperature sensor KMT-14, and an automatic record of the temperature-time curve. The operation of the unit was verified by the integral enthalpy of dissolution in water of crystalline potassium chloride. The agreement between the experimental enthalpies of dissolution of KCl (cr) with the most reliable literature data indicates that there are no systematic errors in the calorimetric system. Samples of para-oxyphenylglycine were weighed on a VLP-200 scale with an accuracy of 2∙10-4 g. The confidence interval of the mean value of ΔH was calculated with a probability of 0.95. A paraxyphenylglycine preparation, «Reachim», was used in the work. The reagent was used without further purification. The RRSU program was used to determine the equilibrium composition of the solutions. Standard enthalpies of combustion and formation of crystalline paraxyphenylglycine were calculated. Thermal effects of dissolution of crystalline paraxyphenylglycine in water and in solutions of potassium hydroxide at 298.15 K were determined with the direct calorimetric method. Standard enthalpies of formation of amino acids and products of their dissociation in aqueous solution were calculated.

Synthesis of 2-Hydroxy-3-(Methyl­cyclo­hexenyl-Isopropyl)-5-Methylbenzyl­amino­ethylnonyl Imidazolines - The Thermostabilizers to Polypropylene

2018 ◽  
Vol 935 ◽  
pp. 155-159
Author(s):  
Z.Z. Aghamaliyev ◽  
Mehriban V. Naghiyeva ◽  
Ch. K. Rasulov
Keyword(s):  
Aqueous Solution ◽  
Hydrochloric Acid ◽  
Amine Salt ◽  
Chemical Characteristics ◽  
Hydrochloride Salt ◽  
Physico Chemical ◽  
Concentrated Solution

2-hydroxy-3-(methylcyclohexenyl-isopropyl)-5-methylbenzylaminoethylnonylimidazolines were synthesized by the interaction of 2-(methylcyclohexynylisopropyl-4-methylphenols and aminoethylnonylimidazoline. Aminocompounds are purified from cycloalkylphenol by transferring them to hydrochloride salt. Further, aqueous solution of the hydrochloric acid amine salt is treated with a concentrated solution of NH4OH and free aminecompounds are isolated. The resulting amine is separated from water by benzene extraction. After benzene distillation, the residue is undergone to distillation under vacuum. Its physico-chemical characteristics and purity of the products are determined. The obtained products are tested as the thermostabilizers to polypropylene.

Study of Physico-chemical Characteristics and Pharmacological Effects of 1-Ethyl-Salicyldene-bis-Ethylene-Diamine and Its Complex with Mn(II)

2019 ◽  
Vol 70 (7) ◽  
pp. 2534-2537
Author(s):  
Gladiola Tantaru ◽  
Mihai Apostu ◽  
Antonia Poiata ◽  
Mihai Nichifor ◽  
Nela Bibire ◽  
...  
Keyword(s):  
Schiff Base ◽  
Chemical Structure ◽  
Antimicrobial Activities ◽  
Ethylene Diamine ◽  
Chemical Characteristics ◽  
Gram Negative Bacteria ◽  
Pharmacological Effects ◽  
Physico Chemical ◽  
Anti Inflammatory ◽  
Inflammatory Effect

The paper presents the synthesis of a new complex combination of a Bis-Schiff base with Mn(II) ions with great potential for antimicrobial and anti-inflammatory activity. A new complex of the Salen-type ligand, 1-ethyl-salicylidene-bis-ethylene diamine was synthetized using Mn(II) ions. The chemical structure was confirmed through 1H-NMR and IR spectroscopy. The antimicrobial activities of the Bis-Schiff base and its complex were tested in comparison with Ampicillin, Chloramphenicol, Tetracycline, Ofloxacin and Nystatin. Those compounds were found to be active against Gram-positive or Gram-negative bacteria, and had an anti-inflammatory effect comparable to that of Indomethacin.

Progress and Prospects in Translating Nanobiotechnology in Medical Theranostics

2020 ◽  
Vol 16 (5) ◽  
pp. 685-707 ◽  
Author(s):  
Amna Batool ◽  
Farid Menaa ◽  
Bushra Uzair ◽  
Barkat Ali Khan ◽  
Bouzid Menaa
Keyword(s):  
Biological Properties ◽  
Chemical Characteristics ◽  
Intrinsic Properties ◽  
The Past ◽  
Profound Influence ◽  
Functionalized Nanomaterials ◽  
Physico Chemical ◽  
Properties Of Materials ◽  
Targeted Drug ◽  
And Performance

: The pace at which nanotheranostic technology for human disease is evolving has accelerated exponentially over the past five years. Nanotechnology is committed to utilizing the intrinsic properties of materials and structures at submicroscopic-scale measures. Indeed, there is generally a profound influence of reducing physical dimensions of particulates and devices on their physico-chemical characteristics, biological properties, and performance. The exploration of nature’s components to work effectively as nanoscaffolds or nanodevices represents a tremendous and growing interest in medicine for various applications (e.g., biosensing, tunable control and targeted drug release, tissue engineering). Several nanotheranostic approaches (i.e., diagnostic plus therapeutic using nanoscale) conferring unique features are constantly progressing and overcoming all the limitations of conventional medicines including specificity, efficacy, solubility, sensitivity, biodegradability, biocompatibility, stability, interactions at subcellular levels. : This review introduces two major aspects of nanotechnology as an innovative and challenging theranostic strategy or solution: (i) the most intriguing (bare and functionalized) nanomaterials with their respective advantages and drawbacks; (ii) the current and promising multifunctional “smart” nanodevices.

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