scholarly journals Reconciliation of Two Cognitive Models in Obsessive-Compulsive Disorder: An fMRI Study

2021 ◽  
Vol 18 (6) ◽  
pp. 545-552
Author(s):  
Seungho Kim ◽  
Sang Won Lee ◽  
Hyunsil Cha ◽  
Eunji Kim ◽  
Yongmin Chang ◽  
...  
Keyword(s):  
Obsessive Compulsive Disorder ◽  
Cognitive Deficit ◽  
Cognitive Models ◽  
Sorting Task ◽  
Card Sorting ◽  
Dysfunctional Beliefs ◽  
Obsessive Compulsive ◽  
Compulsive Disorder ◽  
Belief Models ◽  
Dysfunctional Belief

Objective Although cognitive models of obsessive-compulsive disorder (OCD) fall into two categories: cognitive deficit models and dysfunctional belief models, these approaches have their own ways and have hardly been reconciled. Therefore, this study aimed to investigate the potential relationships between cognitive deficit (using the Wisconsin Card Sorting Task, WCST) and dysfunctional belief (measured by scales of dysfunctional beliefs) mediated by neural activity in OCD patients. Methods Thirty OCD patients and 30 healthy participants performed the WCST condition and a baseline MATCH condition during the 3T-functional magnetic resonance imaging (fMRI) acquisition. Results Engagement of additional frontoparietal networks with poorer performance of WCST was found during the fMRI scan in OCD patients. Selected regions of interest from activated regions have positive relationships with dysfunctional beliefs and with the unacceptable thoughts symptom dimension in the OCD group. Conclusion Findings suggest that alteration in frontoparietal networks related to cognitive deficits can be associated with dysfunctional beliefs while performing conventional neurocognitive tasks and this association with dysfunctional beliefs may be pronounced in the unacceptable thoughts domain-dominant OCD patients.

scholarly journals Action-outcome knowledge dissociates from behavior in obsessive-compulsive disorder following contingency degradation

2018 ◽  
Author(s):  
Matilde M. Vaghi ◽  
Rudolf N. Cardinal ◽  
Annemieke M. Apergis-Schoute ◽  
Naomi A. Fineberg ◽  
Akeem Sule ◽  
...  
Keyword(s):  
Obsessive Compulsive Disorder ◽  
Dysfunctional Beliefs ◽  
Obsessive Compulsive ◽  
Compulsive Disorder ◽  
Causality Judgment ◽  
Habitual Responding ◽  
Outcome Knowledge ◽  
The Relationship ◽  
Dysfunctional Belief ◽  
Explicit Action

ABSTRACTGoal-directed and habitual systems orchestrate action control. In disorders of compulsivity, their interplay seems disrupted and actions persist despite being inappropriate and without relationship to the overall goal. We manipulated action–outcome contingency to test whether actions are goal-directed or habitual in obsessive-compulsive disorder (OCD), the prototypical disorder of compulsivity, in which prominent theories have suggested that dysfunctional beliefs underlie the necessity for compulsive actions.OCD patients responded more than controls when an action was causally less related to obtaining an outcome, indicating excessive habitual responding. Patients showed intact explicit action–outcome knowledge but this was not translated normally into behavior; the relationship between causality judgment and responding was blunted. OCD patients’ actions were dissociated from explicit action-outcome knowledge, providing experimental support for the ego-dystonic nature of OCD and suggesting that habitual action is not sustained by dysfunctional belief.

scholarly journals Relation between executive functions and polymorphisms in COMT, MAO-A, HTTLPR, SLC1A1 and HT2A in a sample of children with Obsessive Compulsive Disorder

2018 ◽  
Author(s):  
Jorge Enrique Avila Campos ◽  
María Cristina Pinto Dussan ◽  
Ángela María Polanco Barreto ◽  
Esneyder Manuel Guerrero ◽  
Rafael Antonio Vásquez Rojas ◽  
...  
Keyword(s):  
Executive Functions ◽  
Obsessive Compulsive Disorder ◽  
Wisconsin Card Sorting Test ◽  
Card Sorting ◽  
Obsessive Compulsive ◽  
Compulsive Disorder ◽  
Gender And Age ◽  
Mao A ◽  
Trail Making ◽  
Sorting Test

AbstractBackgroundObsessive compulsive disorder (OCD) has a complex etiology related to multiple neuropsychological factors. OCD is associated with several candidate genes but results are discordant. The objective was to explore the association between five polymorphisms related to neurotransmitters, the risk of an OCD diagnosis and the performance in four executive functions tests done with Colombian patients diagnosed with this condition.Methods63 patients and 65 controls matched by gender and age were genetically analyzed. For the study of the relation between cognitive function and phenotypes, a subsample of 33 patients and 31 controls was used. The Stroop test, Wisconsin Card Sorting Test (WCST), Tower of London and Trail Making Test (TMT) for executive function assessment were applied and the SNPs analyzed were: COMT (rs4680), MAO-A (rs6323), HTTLPR (rs25531), HT2A (rs6315) and SLC1A1 (rs301434).ResultsDifferences in the conceptualization of the WCST test (p = 0.023) and Stroop interference score (p = 0.041) between cases and controls were obtained. After analyzing the relationship between genotypes and sub-scores of the tests, associations between the presence of MAO-A, SLAC1A1, HTTLPR and HT2A alleles and tests sub-scores were found.DiscussionThis characterization of children with OCD is a new field of work in Colombia and one of the first works performed in Latin America. The sample size and the number of polymorphisms analyzed in this population should be increased.

Cognitive Approaches to Understanding Obsessive Compulsive and Related Disorders

2012 ◽  
Author(s):  
Steven Taylor ◽  
Jonathan S. Abramowitz ◽  
Dean McKay ◽  
Carrie Cuttler
Keyword(s):  
Empirical Evidence ◽  
Obsessive Compulsive Disorder ◽  
Historical Perspective ◽  
Body Dysmorphic Disorder ◽  
Cognitive Models ◽  
Future Research ◽  
Obsessive Compulsive ◽  
Compulsive Disorder ◽  
Conceptual Problems ◽  
Cognitive Approaches

This chapter focuses on cognitive models of obsessive compulsive disorder (OCD) and related disorders. It begins with a historical perspective, in which the antecedents of cognitive models are described. Contemporary cognitive models are then reviewed, predictions derived from the models are identified, and empirical evidence for these predictions is summarized. This is followed by a review of cognitive models of four OC-related disorders: hoarding, hypochondriasis, body dysmorphic disorder, and trichotillomania. Finally, the conceptual problems with cognitive models of OCD and related disorders are identified, suggestions for improvements to the models are made, and potentially fruitful directions for future research are proposed.

scholarly journals Interpersonal Aspects of Responsibility and Obsessive Compulsive Symptoms

2006 ◽  
Vol 34 (2) ◽  
pp. 151-163 ◽  
Author(s):  
Andrea R. Ashbaugh ◽  
Laurie A. Gelfand ◽  
Adam S. Radomsky
Keyword(s):  
Obsessive Compulsive Disorder ◽  
Cognitive Models ◽  
Complex Phenomenon ◽  
Personal Beliefs ◽  
Obsessive Compulsive ◽  
Interpersonal Influences ◽  
Obsessive Compulsive Symptoms ◽  
Compulsive Disorder ◽  
Inflated Responsibility

Obsessive-compulsive disorder (OCD) is associated with an inflated sense of responsibility to prevent harm. Increasingly, it has been recognized that inflated responsibility is a complex phenomenon. The purpose of this study was to examine how interpersonal aspects of responsibility are related to symptoms of OCD. Three new valid and reliable scales assessing beliefs about other people's responsibility, comparative beliefs about responsibility, beliefs about the allocation of responsibility, and beliefs about how others allocate responsibility were used to evaluate interpersonal influences on responsibility. Whereas personal beliefs about responsibility were related to all OCD symptom types, it appears that beliefs about other people's responsibility were related to only a subgroup of symptom types. Furthermore, the belief that one is more responsible than others predicts OC symptoms beyond commonly assessed personal beliefs about responsibility. Finally, individuals with OC symptoms tend to allocate more responsibility to themselves than others, compared to individuals without OC symptoms, despite the fact that individuals with OC symptoms believe that others tend to allocate responsibility equitably. Results are discussed in terms of cognitive models of OCD.

What do low-dysfunctional beliefs obsessive–compulsive disorder subgroups believe?

2010 ◽  
Vol 24 (8) ◽  
pp. 837-846 ◽  
Author(s):  
Heather M. Chik ◽  
John E. Calamari ◽  
Neil A. Rector ◽  
Bradley C. Riemann
Keyword(s):  
Obsessive Compulsive Disorder ◽  
Dysfunctional Beliefs ◽  
Obsessive Compulsive ◽  
Compulsive Disorder

Neuropsychological Outcome from Psychosurgery for Obsessive-Compulsive Disorder

1995 ◽  
Vol 29 (2) ◽  
pp. 293-298 ◽  
Author(s):  
Steven Cumming ◽  
Phillipa Hay ◽  
Teresa Lee ◽  
Perminder Sachdev
Keyword(s):  
Obsessive Compulsive Disorder ◽  
Neuropsychological Test ◽  
Neuropsychological Testing ◽  
Wisconsin Card Sorting Test ◽  
Control Group ◽  
Card Sorting ◽  
Obsessive Compulsive ◽  
Compulsive Disorder ◽  
Memory Functioning ◽  
Response Sets

Seventeen obsessive-compulsive disorder patients treated with psychosurgery were administered a comprehensive neuropsychological test battery. Their performance on neuropsychological testing was compared with that of an age and severity matched sample of 17 OCD sufferers who had not received psychosurgery. The psychosurgery and control groups did not differ in intellectual or memory functioning, consistent with earlier findings that psychosurgery does not reduce global ability estimates. The psychosurgery group performed more poorly than the control group on an adaptation of the Wisconsin Card Sorting Test, demonstrating the possible impact of frontal lobe lesions on the abilities underpinning the formation and shifting of response sets.

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