scholarly journals Treatment of Children and Adolescents with Epilepsy with Atomoxetine

2020 ◽  
Vol 17 (5) ◽  
pp. 412-416
Author(s):  
Kee Jeong Park ◽  
Hyunji Ahn ◽  
Mi-Sun Yum ◽  
Tae-Sung Ko ◽  
Hyo-Won Kim
Keyword(s):  
Children And Adolescents ◽  
Electronic Medical Records ◽  
Medical Records ◽  
Preliminary Evidence ◽  
Common Adverse Event ◽  
Response To Treatment ◽  
Adolescent Psychiatrist ◽  
Korean Children ◽  
Life Threatening ◽  
Atomoxetine Treatment

Objective The objective of this study was to assess the effectiveness and safety of atomoxetine in Korean children and adolescents with epilepsy.Methods We retrospectively reviewed the electronic medical records of 105 children and adolescents with epilepsy treated with atomoxetine. Effectiveness was measured with the Clinical Global Impressions-Severity (CGI-S) and/or Clinical Global Impressions-Improvement (CGI-I) scales at baseline, and after 4 and 12 weeks. We defined response to atomoxetine as a CGI-I score less than three at week 12. Safety was evaluated at each visit, based on clinical assessment by a child and adolescent psychiatrist and reports from participants or their caregivers.Results In total participants (n=105), 33 (31.4%) showed a response to treatment: a significant decrease in CGI-S scale score was observed over 12 weeks of atomoxetine treatment. The most common adverse event (AE) was decreased appetite (n=16, 15.2%), and life-threatening AEs were not observed. Seizure aggravation due to atomoxetine was observed in 7.6% (n=8) of total participants, and one of them discontinued atomoxetine.Conclusion Our results provide preliminary evidence of the effectiveness and safety of atomoxetine in children and adolescents with epilepsy.

scholarly journals Deep Neck Inflammation: Probable Kawasaki Disease in Korean Children

2020 ◽  
Vol 13 (1) ◽  
pp. 77-82
Author(s):  
Sooyeon Lim ◽  
Na Young Lee ◽  
Seung Beom Han ◽  
Dae Chul Jeong ◽  
Jin Han Kang
Keyword(s):  
Computed Tomography ◽  
Kawasaki Disease ◽  
Antibiotic Therapy ◽  
Medical Records ◽  
Empirical Antibiotic Therapy ◽  
Korean Children ◽  
Life Threatening ◽  
Deep Neck Abscess ◽  
Deep Neck Infections ◽  
Prompt Diagnosis

Objectives. Deep neck infections (DNIs) can cause life-threatening complications, and prompt diagnosis and management are necessary. Kawasaki disease (KD) may be accompanied by deep neck inflammation; making it difficult to distinguish from DNIs. This study was performed to evaluate clinical features and outcomes of children with parapharyngeal and retropharyngeal inflammation.Methods. Medical records of the children diagnosed with parapharyngeal and retropharyngeal cellulitis or abscess using cervical computed tomography (CT) between 2013 and 2017 were retrospectively reviewed.Results. A total of 47 children were diagnosed with parapharyngeal and retropharyngeal inflammation. Eleven (23.4%) of them were eventually diagnosed with KD, and 36 (76.6%) were diagnosed with DNIs. There were no significantly different clinical and laboratory characteristics on admission between children diagnosed with KD and DNIs; however, significantly more children with KD were febrile for ≥3 days after admission compared to those with DNIs (P=0.009). Deep neck abscesses on CT were observed in 16 children with DNIs (44.4%) and in no child with KD (P=0.009). Among the 36 children with DNIs, 30 (83.3%) were cured with antibiotic therapy only.Conclusion. A quarter of children presenting with deep neck inflammation were diagnosed with KD. KD should be considered in children showing deep neck inflammation unresponsive to empirical antibiotic therapy after 3 days, especially in those presenting with deep neck cellulitis rather than deep neck abscess.

Adolescent Substance Use Screening Integrated With Electronic Medical Records

2014 ◽  
Author(s):  
C. McKenna ◽  
B. Gaines ◽  
C. Hatfield ◽  
S. Helman ◽  
L. Meyer ◽  
...  
Keyword(s):  
Substance Use ◽  
Electronic Medical Records ◽  
Medical Records ◽  
Adolescent Substance Use ◽  
Adolescent Substance

908-P: Predictive Model for Glycemic Level of People with Diabetes Mellitus Using Data Extracted from Electronic Medical Records in Primary Care

Diabetes ◽  
2020 ◽  
Vol 69 (Supplement 1) ◽  
pp. 908-P
Author(s):  
SOSTENES MISTRO ◽  
THALITA V.O. AGUIAR ◽  
VANESSA V. CERQUEIRA ◽  
KELLE O. SILVA ◽  
JOSÉ A. LOUZADO ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Primary Care ◽  
Predictive Model ◽  
Electronic Medical Records ◽  
Medical Records ◽  
Glycemic Level ◽  
Using Data
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