scholarly journals Sneddon Syndrome: Livedo Reticularis and Ischemic Stroke

2021 ◽  
Vol 1 (37) ◽  
pp. 80-82
Author(s):  
Ahmet Bugrul ◽  
Hasan Huseyin Kozak ◽  
Mustafa Altas
Keyword(s):  
Ischemic Stroke ◽  
Livedo Reticularis ◽  
Sneddon Syndrome

WED 253 An atypical presentation of sneddon syndrome

2018 ◽  
Vol 89 (10) ◽  
pp. A36.2-A36
Author(s):  
Jonathan Cleaver ◽  
Shelley Renowden ◽  
Mario Teo ◽  
Philip Clatworthy
Keyword(s):  
Skin Biopsy ◽  
Internal Carotid ◽  
Clinical Course ◽  
Cerebral Arteries ◽  
Livedo Reticularis ◽  
Moyamoya Syndrome ◽  
Stroke In Young Adults ◽  
Hands And Feet ◽  
Sneddon Syndrome ◽  
Stroke In Young

A 50-year-old female was admitted following a subacute and increasing headache, numbness in both hands and feet, generalised weakness and confusion.An MRI brain revealed an acute left temporal infarct with multi-focal established infarcts. MR angiography demonstrated marked occlusive disease affecting terminal internal carotid artery and both middle cerebral and posterior cerebral arteries, in a potential Moyamoya pattern.Lumbar puncture, extensive blood tests and echocardiography were unremarkable. A skin biopsy showed intimal thickening of the deep dermal arteries compatible with a diagnosis of Sneddon Syndrome. Livedo reticularis was absent and antiphospholipid antibodies negative. Antiplatelet therapy only was commenced given her seronegativity and Moyamoya.DiscussionSneddon syndrome is an uncommon disorder, characterised as generalised livedo reticularis with stroke (Sneddon, 1965). It is an increasingly recognised cause of ischaemic stroke in young adults, however, its clinical course remains poorly defined in the literature (Boesch et al. 2003). It is increasingly associated with Moyamoya syndrome, posing a challenge in terms of anticoagulation in these patients (Fierini et al. 2015). To our knowledge, this is only the second reported case without livedo reticularis (Marianetti et al. 2011) - highlighting the importance of skin biopsy - and the first with this clinical and radiological combination.

scholarly journals Cognitive and psychiatric changes as first clinical presentation in Sneddon syndrome

2018 ◽  
Vol 12 (2) ◽  
pp. 216-219
Author(s):  
Giorgio Fabiani ◽  
Raul Martins Filho ◽  
Gelson Luis Koppe ◽  
Zeferino Demartini Jr ◽  
Luana Antunes Maranha Gatto
Keyword(s):  
Young Patients ◽  
Unknown Origin ◽  
Livedo Reticularis ◽  
Personality Changes ◽  
Dementia Syndrome ◽  
History Of ◽  
Progressive Cognitive Impairment ◽  
Typical Skin ◽  
Sneddon Syndrome ◽  
Rule Out

ABSTRACT Sneddon syndrome (SS) is a rare progressive non-inflammatory thrombotic vasculopathy affecting small/medium-sized blood vessels of unknown origin. It is strongly associated with the presence of antiphospholipid antibodies (AA). The presence of livedo reticularis and cerebrovascular disease are hallmark features. The condition is far more common in young women. We report a case of SS in a 43 year-old male with a two-year history of progressive cognitive impairment consistent with dementia syndrome, and major personality changes, besides livedo reticularis and cerebral angiographic pattern of vasculitis. AA were borderline. The recognition of skin blemishes that precede strokes should raise the hypothesis of SS. AA are elevated in more than half of cases, but their role in the pathogenesis or association of positive antibodies and SS remains unclear. Dementia syndrome in young patients should be extensively investigated to rule out reversible situations. Typical skin findings, MRI and angiography may aid diagnosis.

scholarly journals 557 Recurrent cerebral venous sinus thromboses (CVST’s) and livedo reticularis rash – A case of sneddon syndrome

2021 ◽  
Author(s):  
Vanita Shukla ◽  
Virendra RS Singh ◽  
Vindra A Singh ◽  
Leonardo Akan ◽  
Nicole St Louis ◽  
...  
Keyword(s):  
Livedo Reticularis ◽  
Venous Sinus ◽  
Sneddon Syndrome

scholarly journals Sneddon’s Syndrome: clinical case

2020 ◽  
Vol 1 (1) ◽  
pp. 14-15
Author(s):  
Elharrouni A ◽  
Douhi Z ◽  
Achhboune K ◽  
Baybay H ◽  
Elloudi S ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Ischemic Stroke ◽  
Family History ◽  
Skin Biopsy ◽  
High Blood Pressure ◽  
Antiphospholipid Antibodies ◽  
Clinical Case ◽  
Antiplatelet Agents ◽  
Negative Opinion ◽  
Sneddon Syndrome

We report a 40-year-old female. The high blood pressure was found in Family history, hospitalized in neurology for recurrent ischemic stroke so the etiological assessment was negative, opinion was sought for lesions of livedo at the level of the members back to 2 years without the concept of miscarriage or Raynaud’s phenomenon, neither photosensitivity nor a dry syndrome. Dermatologic examination showed dusky erythematous to violaceous, irregular, broken circular segments, resulting in a seemingly larger pattern, located on limbs, trunk, and buttocks, exaggerated by the cold and persistent on warming. A report looking for the antiphospholipid antibodies syndrome was positive and the skin biopsy was in favor of a Sneddon syndrome. The patient was treated by anticoagulants and antiplatelet agents with good evolution.

Photosensitive livedo reticularis

1973 ◽  
Vol 108 (1) ◽  
pp. 100-101 ◽  
Author(s):  
D. F. Marion
Keyword(s):  
Livedo Reticularis
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