scholarly journals Maggot Debridement Therapy (MDT) for Treatment of Cutaneous Leishmaniasis Wound using Lucilia serricata Larvae in Iran: Case Reports

2022 ◽  
Vol 30 (1) ◽  
pp. 1-8
Author(s):  
Asghar Nasiri ◽  
Elham Jahanifard ◽  
Mona Sharififard ◽  
Reza Arjmand ◽  
Sima Rasai ◽  
...  
Keyword(s):  
Cutaneous Leishmaniasis ◽  
Case Reports ◽  
Maggot Debridement Therapy

scholarly journals Cutaneous Leishmaniasis in a Bangladeshi Adult: A Case Report

2015 ◽  
Vol 25 (2) ◽  
pp. 78-80
Author(s):  
Abdur Rahim ◽  
Md Moniruzzan ◽  
Rashedul Hassan ◽  
Monira Sarmin ◽  
Md Abdullah Yusuf ◽  
...  
Keyword(s):  
Cutaneous Leishmaniasis ◽  
Plasma Cells ◽  
Case Reports ◽  
Ring Finger ◽  
Clinical History ◽  
The Body ◽  
Nasal Bridge ◽  
Cutaneous Tuberculosis ◽  
Exposed Part ◽  
Ulcerative Lesions

Cutaneous leishmaniasis is rare in Bangladesh although very few case reports are seen since last few years. But Visceral Leishmaniasis (kala azar) and PKDL are common in this region. In country like ours where tuberculosis and leprosy are more prevalent Cutaneous Leishmaniasis is very likely to be mistreated as Cutaneous tuberculosis especially lupus vulgaris or leprosy. Cases of Cutaneous Leishmaniasis (CL) are usually imported to Bangladesh from other endemic countries. A patient from an endemic area of Cutaneous Leishmaniasis, a non-healing nodulo-ulcerative lesion on exposed part of the body, dermal infiltration with lymphocytes, histiocytes and plasma cells and demonstration of intracellular parasites in lesional skin establish the diagnosis of Cutaneous Leishmaniasis. We present a case of Cutaneous Leishmaniasis in a Bangladeshi adult working in Saudi Arabia for more than 15 years. He presented with multiple ulcerative lesions on nasal bridge, right ear lobule and dorsum of right ring finger. The patient’s clinical history, morphology of the lesions and laboratory analysis were consistent with Cutaneous Leishmaniasis, a rare entity for Bangladesh.Bangladesh J Medicine Jul 2014; 25 (2) : 78-80

scholarly journals Is there an association between cutaneous leishmaniasis and skin cancer? A systematic review

2019 ◽  
Vol 4 ◽  
pp. 110
Author(s):  
Rodrigo M. Carrillo-Larco ◽  
J. Gonzalo Acevedo-Rodriguez ◽  
Carlos Altez-Fernandez ◽  
Karol Ortiz-Acha ◽  
Cesar Ugarte-Gil
Keyword(s):  
Systematic Review ◽  
Skin Cancer ◽  
Cutaneous Leishmaniasis ◽  
Observational Studies ◽  
Communicable Disease ◽  
Case Reports ◽  
Communicable Diseases ◽  
Neglected Diseases ◽  
Non Communicable Diseases ◽  
Co Morbidity

Background: Cutaneous leishmaniasis is a prevalent communicable disease in low- and middle-income countries, where non-communicable diseases like skin cancer are on the rise. However, the study of multi-morbidity or co-morbidity between communicable and non-communicable diseases is limited, and even null for some tropical or neglected diseases. Nevertheless, looking at these conditions together instead of as isolated entities in places where these illnesses exist, could show new prevention and treatment paths. We aimed to summarize and critically appraise the epidemiological evidence on the association between cutaneous leishmaniasis and skin cancer. Methods: Following the PRISMA guidelines, we conducted a systematic review using five search engines (Embase, Medline, Global Health, Scopus and Web of Science). We sought observational studies in which the outcome was skin cancer whilst the exposure was cutaneous leishmaniasis; these conditions should have had laboratory or pathology confirmation. Results: No epidemiological investigations have studied the association between cutaneous leishmaniasis and skin cancer. Most of the evidence about the association of interest is still based on case reports and other clinical observations rather than strong epidemiological observational studies. Conclusions: Research is much needed to verify the repeatedly clinical observation that cutaneous leishmaniasis may be a risk factor for skin cancer. This evidence could inform and guide early diagnosis or prevention of skin cancer in survivors of cutaneous leishmaniasis or where cutaneous leishmaniasis is still highly prevalent. Registration: PROSPERO ID CRD42018111230; registered on 16/10/18.

scholarly journals 1172 Maggot Debridement Therapy (MDT) In Treating Group A Streptococcus Necrotizing Fasciitis of The Lower Limb as A Part of Multimodal Therapy

2021 ◽  
Vol 108 (Supplement_6) ◽  
Author(s):  
M Haroon ◽  
O Alsahaf ◽  
A Asure ◽  
E Eguare
Keyword(s):  
Necrotizing Fasciitis ◽  
Bacterial Infections ◽  
Complex Disease ◽  
Case Reports ◽  
Skin Grafting ◽  
Necrotising Fasciitis ◽  
Treatment Modalities ◽  
High Morbidity ◽  
Wound Debridement ◽  
Maggot Debridement Therapy

Abstract Background Medical-grade maggots have been commercially available recently and today there is a resurge interest in MDT. They are approved for debridement of wounds with necrotic tissue, including pressure ulcers, venous ulcers. However, for necrotising fasciitis, it has been used with precaution due to the complexity of the disease. In our practice, Maggot debridement therapy (MDT) has been proven to be very effective in the treatment of gram-positive bacterial infections. Worldwide, Case reports on the results of 15 patients with necrotizing fasciitis treated with MDT have been reported. However, in current practice, Maggot Debridement therapy has not been widely applied. Case presentation A 63-year-old lady admitted to a general surgery ward with uncomplicated cellulitis of the right leg. After 2 days, the patient then was diagnosed with Necrotising fasciitis which was treated with wound debridement. Postoperative histopathology specimen confirmed necrotizing fasciitis V.A.C. VERAFLO™ Therapy was used postoperatively followed by two more debridement sessions. To reduce the need for further surgical debridement Maggot Debridement Therapy was started. Over the next 3 weeks, six sessions of Maggot Debridement therapy were applied to the infected area. Skin grafting then was performed 3 months later. The patient then discharged home with regular surgical fellow up. Conclusions NF is a complex disease, associated with high morbidity and mortality. Multimodal therapies are essential to achieve aggressive yet conservative wound debridement with preservation of viable tissue. This case report showed that MDT is a feasible, safe, cost-effective option that to be added to the other treatment modalities

scholarly journals Efficacy of photodynamic therapy in the treatment of cutaneous leishmaniasis

2019 ◽  
Vol 26 (06) ◽  
Author(s):  
Mahvish Aftab Khan ◽  
Sehrish Aftab ◽  
Nadia Shams ◽  
Rahmat Ullah Khan
Keyword(s):  
Photodynamic Therapy ◽  
Cutaneous Leishmaniasis ◽  
Case Reports ◽  
Cross Sectional Study ◽  
Cross Sectional ◽  
Ethical Approval ◽  
Mean Size ◽  
Duration Of Disease ◽  
Photosensitizing Agent ◽  
Study Setting

Introduction: A limited number of case reports have studies the efficacy of Photodynamic Therapy (PDT) in management of Cutaneous Leishmaniasis (CL). Topical PDT is an innovative mode of therapy that works on principle of selective uptake of photosensitizing agent by CL lesions. Current study was conducted to determine efficacy of topical photodynamic therapy of CL. Study Design: Descriptive cross sectional study. Setting: Dermatology outdoor clinic PIMS Islamabad. Period: July 2015 to Jan 2016. Materials & Methods: Total 75 patients (>12 years) of either gender with biopsy proven CL lesions were included after ethical approval.  Pregnant or lactating women, those with sensitivity to light or photo sensitizer were excluded. The selected cases were administered once a week sessions of topical 5-ALA PDT therapy. This therapy was continued till 4 weeks and efficacy was observed at 6th week; efficacy labeled as yes if there was no erythema with resolution of papules, plaques or nodules, surrounded by normal healthy skin clinically and the histo-pathological smears revealing absence of amastigotes, otherwise labeled as non-effective. Results: Mean age was 24.37+7.43 years. There were 44(58.67%) females and 31(41.33%) males. Mean duration of disease was 40.29+11.73 days and mean size of lesion was 19.69+9.88 mm. Effective PDT outcome was seen in 67(89.33%) patients at 6th week of therapy. Conclusion: This study concluded that topical photodynamic therapy is an effective method for treatment of Cutaneous Leishmaniasis.

scholarly journals New human case reports of cutaneous leishmaniasis by Leishmania (Viannia) naiffi in the Amazon region, Brazil

2017 ◽  
Vol 47 (1) ◽  
pp. 47-52 ◽  
Author(s):  
Luanda de Paula FIGUEIRA ◽  
Fabiane Veloso SOARES ◽  
Roberto Daibes NAIFF JÚNIOR ◽  
Alana Cristina VINHOTE-SILVA ◽  
Susi Simas da SILVA ◽  
...  
Keyword(s):  
Cutaneous Leishmaniasis ◽  
Upper Limb ◽  
Disease Transmission ◽  
Medical Literature ◽  
Clinical Course ◽  
Case Reports ◽  
Human Case ◽  
Isoenzyme Analysis ◽  
First Case ◽  
Human Cutaneous Leishmaniasis

ABSTRACT Few cases of human cutaneous leishmaniasis (CL) caused by Leishmania naiffi were described in the medical literature. The aim of this study was to report and analyze new cases of L. naiffi in the period between the years 1992 to 2011. The strains were characterized by isoenzyme analysis. All patients assisted had small lesions; ranging from 1.0x1.0 mm and 13.5x11.5 mm. The lesions observed were widely distributed: 55.5% on the lower limb, 5.5% in the abdominal area, 16.6% on upper limb and 22.2% in upper limb and back. Seventy-two percent of patients had ulcerated lesions. Clinical course of the disease varied from 1 to 10 months. According to gender, most infected individuals were men (83.3%). The patients came from Amazonas (10), Pará (01) and Rondônia (01), north States of Brazil. Five patients were infected in experimental stations of the National Institute of Amazonian Research (INPA). Although the results of this study were similar to other reports in the literature, some of the patients had more of one skin lesion. It is also reported the first case of CL caused by L. naiffi in the State of Rondônia and identified an area of disease transmission in the experimental station of INPA.

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