scholarly journals Easy and New Chemical Synthesis of Stable Nano Sliver using Propylene Glycol and Glycerin as Reducing Agents

2018 ◽  
Vol 36 (2B) ◽  
Keyword(s):  
Chemical Synthesis ◽  
Propylene Glycol ◽  
Reducing Agents

Chemical synthesis of disulfide surrogate peptides by using beta-carbon dimethyl modified diaminodiacids

2021 ◽  
Author(s):  
jibin cui ◽  
xiaoxiong wei ◽  
Rui Zhao ◽  
Huixia Zhu ◽  
Jing Shi ◽  
...  
Keyword(s):  
Chemical Synthesis ◽  
Reducing Agents ◽  
Disulfide Bridges ◽  
Promising Strategy ◽  
The Stability

The replacement of disulfide bridges with metabolically stable isosteres is a promising strategy to improve the stability of disulfide-rich polypeptides towards reducing agents and isomerases. Diaminodiacid-based strategy is one of...

2-Methoxypropan-1-ol. Documentation of proposed values of occupational exposure limits (OELs)

2021 ◽  
Vol 37 (2) ◽  
pp. 5-26
Author(s):  
Anna Kilanowicz-Sapota ◽  
Michał Klimczak
Keyword(s):  
Occupational Exposure ◽  
Chemical Synthesis ◽  
Propylene Glycol ◽  
Birth Defects ◽  
Methyl Ether ◽  
Manufacturing Process ◽  
Toxic Effects ◽  
Occupational Exposure Limits ◽  
Exposure Limits ◽  
Glycol Methyl Ether

2-Methoxypropan-1-ol is a by-product of a propylene glycol methyl ether (PGME) manufacturing process, in which it is an impurity at concentrations up to 5%. 2-Methoxypropan-1-ol as a PGME impurity can occur in industry in paints solvents, varnishes, dyes, inks, adhesion agents, ingredients in cleaning formulations and chemical synthesis intermediates. It may also occur as an impurity in cosmetics, although its use in these products is prohibited. At occupational exposure, 2-methoxypropan-1-ol may be absorbed through inhalation and skin. There are no data on the number of people exposed to this compound in Poland and no data on its toxic effects in humans. There is only one study that showed a statistically significant increase in the occurrence of birth defects in children of mothers exposed to 2-methoxypropan-1-ol. The proposed MAC value for 2-methoxypropan-1-ol (20 mg/m3) is based on the systemic toxicity demonstrated in a study on pregnant rabbits (NOAEC value of 1335 mg/m3). Due to its irritant effects, STEL value of 40 mg/m3 and “I” notation are also proposed. There is no basis for establishing a BEI value. Since dermal exposure may contribute significantly to the absorption of 2-methoxypropan-1-ol by workers, a "skin" notation is also required.

Chemical synthesis of proteinoids: Part 1

1964 ◽  
Author(s):  
Sidney W. Fox ◽  
Kaoru Harada ◽  
Gottfried Krampitz ◽  
Tadao Hayakawa ◽  
Charles Ray Windsor
Keyword(s):  
Chemical Synthesis

Molecular dynamics of poly(propylene) glycol in nanometer confinements

2000 ◽  
Vol 10 (PR7) ◽  
pp. Pr7-271-Pr7-274 ◽  
Author(s):  
A. Schönhals ◽  
H. Goering ◽  
K.-W. Brzezinka ◽  
Ch. Schick
Keyword(s):  
Molecular Dynamics ◽  
Propylene Glycol ◽  
Poly Propylene

Methods for the Concentration of Bovine Ac-Globulin (Factor V)

1961 ◽  
Vol 06 (03) ◽  
pp. 435-444 ◽  
Author(s):  
Ricardo H. Landaburu ◽  
Walter H. Seegers
Keyword(s):  
Room Temperature ◽  
Barium Carbonate ◽  
Deae Cellulose ◽  
Reducing Agents ◽  
Factor V ◽  
Isoelectric Precipitation ◽  
Stabilizing Agent ◽  
Bovine Plasma ◽  
The Stability

SummaryAn attempt was made to obtain Ac-globulin from bovine plasma. The concentrates contain mostly protein, and phosphorus is also present. The stability characteristics vary from one preparation to another, but in general there was no loss before 1 month in a deep freeze or before 1 week in an icebox, or before 5 hours at room temperature. Reducing agents destroy the activity rapidly. S-acetylmercaptosuccinic anhydride is an effective stabilizing agent. Greatest stability was at pH 6.0.In the purification bovine plasma is adsorbed with barium carbonate and diluted 6-fold with water. Protein is removed at pH 6.0 and the Ac-globulin is precipitated at pH 5.0. Rivanol and alcohol fractionation is followed by chromatography on Amberlite IRC-50 or DEAE-cellulose. The final product is obtained by isoelectric precipitation.

Sign in / Sign up

Export Citation Format

Share Document