scholarly journals UJI EFEKTIVITAS ANTIINFLAMASI KRIM TIPE M/A DARI EKSTRAK ETANOL DAUN RANDU (Ceiba pentandra.(L) Gaertn ) PADA HEWAN UJI MENCIT PUTIH JANTAN (Mus musculus.L)

2021 ◽  
Vol 4 (1) ◽  
pp. 66
Author(s):  
Setya Enti Rikomah ◽  
Luky Dharmayanti ◽  
Melandika Dwi Sakinah
Keyword(s):  
Ceiba Pentandra ◽  
One Way Anova

<p>Daun Tanaman Randu (<em>Ceiba Pentandra .(L) Gaertn</em>) dimasyarakat digunakan sebagai obat, salah satunya untuk antiinflamasi. Daun randu mempunyai kandungan flavonoid sebagai senyawa metabolit sekunder yang diduga berperan sebagai antiinflamasi. Ekstrak etanol daun randu telah diformulasikan menjadi sediaan krim. Tujuan dari penelitian ini adalah untuk mengetahui efektifitas antiinflamasi sediaan krim ekstrak etanol daun randu pada mencit jantan putih.</p><p>Efektifitas antiinflamasi diuji menggunakan metode <em>Inflammation-associated edema</em>. Hewan uji yang digunakan sebanyak 30 ekor mencit jantan putih yang dibagi menjadi 6 kelompok yaitu kontrol normal,  kontrol negatif (F0), kontrol positif (Krim Hidrokortison), dan kelompok perlakuan krim ekstrak etanol daun randu F1 (10%), F2 (15%), dan F3 (20%). Pengamatan dan pengukuran volume tebal lipat kulit punggung mencit menggunakan jangka sorong digital dilakukan saat sebelum diinduksi dan setelah diinduksi karagenan 2%. Pengamatan penurunan volume tebal lipat kulit punggung mencit dilakuan setiap satu jam sekali selama 6 jam. Data yang didapatdiolahdandianalisa menggunakan <em>one-way anova</em>danuji <em>duncan</em>dengan tingkat kepercayaan 95%.</p><p>Hasil uji <em>one-way anova </em>menunjukan tidak terdapat perbedaan yang nyata antar kelompok perlakuan (0,967&gt;0,05). Hasil uji <em>duncan</em> menunjukan bahwa antar kelompok perlakuan memiliki efektivitas antiinflamasi yang hampir sama.</p><p><strong> </strong></p><p><strong>Kata kunci: Randu, Antiinflamasi, Krim, <em>Inflammation-associated edema.</em></strong></p>

scholarly journals Solasodine and Gosipol Effectivity as a Male Contraception Inhibit LH Expression and Spermatogenesis in Rat

2019 ◽  
Vol 1 (2) ◽  
pp. 51-59
Author(s):  
Desi Wulansari ◽  
◽  
Yudit Oktanella ◽  
Viski Fitri Hendrawan ◽  
Galuh Chandra Agustina ◽  
...  
Keyword(s):  
Disease Transmission ◽  
Population Control ◽  
Sperm Concentration ◽  
Wild Animal ◽  
Solanum Torvum ◽  
Ceiba Pentandra ◽  
Animal Populations ◽  
Canine Population ◽  
Result Show ◽  
One Way Anova

Rabies related to increasing canine population in Bali. Uncontrolled wild animal populations caused disease transmission from animal to human. Various attempt at population control are carried out such as the use of natural contraception. Some compounds are known to have potential as antifertility are solasodine and gosipol. Solasodine is known have an antifertility affect. Gosipol, fenolic compound in Ceiba pentandra, inhibits spermatogenesis, reduce sperm concentration, motility and viability. This research aims to compare effectiveness of terong cepoka and Ceiba pentandra as antifertility. This research was conducted at Mei-November 2018. Eight-teen rats were used in this study and divided into three groups: control, P1 extract Solanum torvum 1g/kg BW and P2 extract Ceiba pentandra 0,1g/kg BW PO. Rats were treated with extract for 10 days and euthanazed at day 11. Testis were collected for histopathology using HE staining to observe spermatogenesis and using immunohistochemistry to observe LH expression. The result are analyzed using one way ANOVA P<0.05. the result show that extract solanum torvum 1g/kg BW and ceiba pentandra 0,1g/kgBW cannot reduce spermatogenesis and LH expression. This study used crude extract which still consist any other compound like antioxidant. Future study we need use isolated and pure solasodine and gosipol.

scholarly journals EFEKTIVITAS ANALGETIK KRIM TIPE M/A EKSTRAK ETANOL DAUN RANDU (Ceibapentandra (L) Gaertn) PADA HEWAN UJI MENCIT JANTAN

2022 ◽  
Vol 5 (1) ◽  
pp. 77-92
Author(s):  
Setya Enti Rikomah ◽  
Devi Novia ◽  
Muhammad Fadhly
Keyword(s):  
White Male ◽  
Ethanol Extract ◽  
Positive Control ◽  
Negative Control ◽  
Plant Leaves ◽  
Treatment Groups ◽  
Ceiba Pentandra ◽  
The One ◽  
One Way Anova ◽  
Better Than

Randu plant leaves (Ceiba pentandra (L) Gaertn) are commonly used in traditional medicine, one of which is an analgesic with secondary metabolites which are thought to be analgesics, namely flavonoids. The purpose of this study was to determine the analgesic effectiveness of the ethanol extract cream of randu leaves (Ceiba pentandra (L) Gaertn) in white male mice (Mus musculus). The research on the analgesic effectiveness of the ethanol extract cream of randum leaves used the hot plate method and used male white mice as the experimental animal media. The soles of the hind legs of the mice were heated over hot plated with a temperature of 550C then the test animals were given the treatment which was divided into 5 treatment groups, namely positive control (Conterpain cream), negative control (F0), F1 (10%), F2 (15%), F3 (20%) and 1 normal group. The response of mice was calculated every 30 minutes in 120 minutes. The data obtained were analyzed using the one-way ANOVA statistical test followed by the Duncan test with a confidence level of 99%. The results of the one-way ANOVA test showed that there were significant differences between treatment groups (0.00 <0.05). The results of the Duncan test showed that the group that provided the best analgesic effectiveness was F2 (15%) but not better than Positive Control.

scholarly journals EFFECTIVENESS ANTIPYRETIK RANDU SYRUP LEAF EXTRACT ETHANOL (Ceiba pentandra L) ONWHITE MALE Mice (Mus musculus)

2019 ◽  
Vol 6 (2) ◽  
Author(s):  
Setya Enti Rikomah
Keyword(s):  
Mus Musculus ◽  
Leaf Extract ◽  
Male Mice ◽  
Ceiba Pentandra ◽  
One Way Anova

Tumbuhan sebagai obat tradisional masih sangat di butuhkan di masyarakat Indonesia terutama di daerah pedesaan yang masih kaya dengan keanekaragaman tumbuhannya. Tanaman randu ( Ceiba pentandra L ) telah banyak digunakan di dunia kefarmasian dalam berbagai bentuk sediaan salah satunya sirup. Penelitian ini bertujuan untuk mengetahui efektifitas antipyretik sirup ekstrak etanol daun randu.    Penelitian ini menggunakan metode induksi vaksin DPT-Hb 0,022/20gr BB mencit sebagai induksi demam, menggunakan 5 kelompok perlakuan yaitu Kontrol Positif (Parasetamol), Kontrol Negatif (F0), Formula I (5%), Formula II (10%), Formula III (15%). Pengamatan dilakukan setiap 30 menit selama 180 menit. Data di analisa menggunakan One Way Anova dengan taraf kepercayaan 95%.    Hasil penelitian di dapatkan semua perlakuan Signifikan dengan nilai P 0.000 <0,05. Hasil Duncan menunjukkan Formula III memiliki efek Antipyretik lebih baik dibandingkan kontrol positif, formula II, kontrol negatif, formula I.

scholarly journals PERBEDAAN PENURUNAN KANDUNG FE (BESI) DI SUMUR GALI MENGGUNAKAN KARBON AKTIF BIJI KAPUK (CEIBA PENTANDRA) SEBAGAI ADSORBEN

2020 ◽  
Vol 8 (2) ◽  
pp. 65-70
Author(s):  
RIANG ADEKO ◽  
ANDRIANA MARWANTO
Keyword(s):  
Ceiba Pentandra ◽  
One Way Anova ◽  
Quasi Experiment

Air merupakan senyawa kimia yang sangat penting bagi kehidupan manusia dan makhluk hidup lainnya. Salah satu pencemar kimia yang paling banyak ditemukan dalam air adalah Fe. Salah satu cara yang dapat dilakukan untuk menurunkan kadar Fe adalah dengan proses adsorbsi. Tujuan penelitian ini untuk mengetahui ketebalan arang aktif  biji kapuk (ceiba pentandra) paling efektif dalam menurunkan Fe pada air sumur gali. Jenis penelitian yang dilakukan adalah quasi experiment, subjek penelitian ini adalah air sumur gali dan biji kapuk, dan objek adalah kadar Fe. Analisis data menggunakan uji One Way Anova dan uji Benferroni. Hasil penelitian ini menunjukkan bahwa adanya penurunan kadar Fe pada Air Sumur Gali setelah dilakukan adsorbsi, yaitu sebesar 44,54% - 74,09% pada setiap ketebalan. Dari hasil analisis data maka didapatkan ketebalan arang aktif biji kapuk paling efektif untuk menurunkan kadar Fe adalah 50 cm. Diharapkan peneliti lain juga memeriksa dan memperhatikan faktor-faktor yang dapat mempengaruhi proses adsorbsi.

Efektifitas Ekstrak Daun Sirih Hijau (Piper Betle) sebagai Insektisida Nabati terhadap Mortalitas Lalat Rumah (Musca domestica)

2019 ◽  
Vol 10 (2) ◽  
pp. 44-50
Author(s):  
Rinaldi Daswito ◽  
Rima Folentia ◽  
M Yusuf MF
Keyword(s):  
Musca Domestica ◽  
Leaf Extract ◽  
Effective Concentration ◽  
P Value ◽  
Piper Betle ◽  
Microbiology Laboratory ◽  
House Flies ◽  
Betel Leaf ◽  
The One ◽  
One Way Anova

One of the diseases that can be transmitted by flies is diarrhea. Green betel leaf contains essential oils, chavicol, arecoline, phenol, and tannins which function as plant-based insecticides. This study aimed to determine the effectiveness of green betel leaf extract (Piper betel) as a plant-based insecticide on the number of mortality of house flies (Musca domestica). The research was an experimental study used After Only Design used the One Way Anova test with a 95% confidence level. The samples used were 360 ​​house flies. Each treatment of 30 house flies with 4 repetitions and used three concentrations of green betel leaf extract (25%, 50%, 75%). The study was conducted at the Chemistry and Microbiology Laboratory of Health Polytechnic Tanjungpinang, while the location of the fly collection was at the Tokojo Garbage Collection Station in Bintan Regency. The number of mortality of house flies at a concentration of 25% was 81 heads (67.5%), 50% concentrations were 93 heads (77.5%), and at a concentration of 75% were 103 heads (85.83%). There was an effect of green betel leaf extract on the mortality of house flies (p-value 0.0001 <0.05) with the most effective concentration of 75%. Further research is needed to obtain a finished product utilizing green betel leaf extract as a vegetable insecticide, especially in controlling the fly vector. Need further research on the use of green betel leaf extract as a vegetable insecticide controlling the fly vector by taking into account the amount of spraying and the age of the fly.   Keywords: Green betel leaf extract , organic insecticide, houseflies

Pengaruh Pemberian Ekstrak Rumput Laut Merah (Kappaphycus alvarezii) terhadap Kadar LDL Pada Tikus Putih (Rattus Norvegicus) Jantan Galur Wistar Yang Diberi Diet Tinggi Lemak

2018 ◽  
Vol 15 (2) ◽  
pp. 112
Author(s):  
MENTARI AMENDA SAPUTRI ◽  
HERIN SETIANINGSIH
Keyword(s):  
Rattus Norvegicus ◽  
Kappaphycus Alvarezii ◽  
Control Group ◽  
Control Group Design ◽  
Group Design ◽  
Post Test ◽  
One Way Anova ◽  
Test Control

<p class="Default">Penyakit kardiovaskular merupakan penyebab kematian nomor satu di dunia. Gaya hidup masyarakat terutama dalam mengkonsumsi diet yang tidak sehat dapat meningkatkan kadar LDL yang dapat menyebabkan  penyakit kardiovaskular. Rumput laut merah (<em>Kappaphycus alvarezii</em>)<em> </em>yang banyak dibudidayakan di Indonesia mengandung flavonoid dan triterpenoid yang diduga dapat menurunkan kadar LDL. Penelitian ini bertujuan untuk mengetahui pengaruh pemberian ekstrak rumput laut merah (<em>Kappaphycus alvarezii</em>) <em> </em>terhadap kadar LDL pada tikus putih (<em>Rattus norvegicus</em>) jantan galur Wistar yang diberi diet tinggi lemak. Penelitian ini adalah penelitian eksperimental murni laboratorik dengan rancangan penelitian <em>Post Test Control Group Design. </em>Sampel yang digunakan adalah 24 ekor tikus putih (<em>Rattus norvegicus</em>) jantan galur Wistar yang dibagi ke dalam tiga kelompok: kelompok yang diberi diet standar selama 28 hari (K1), kelompok yang diberi diet tinggi lemak selama 28 hari (K2), dan kelompok yang diberi diet tinggi lemak selama 28 hari dan pada hari ke-15 sampai hari ke-28 diberi ekstrak rumput laut merah (<em>Kappaphycus alvarezii</em>) dengan dosis 140mg/200grBB/hari (K3). Hasil analisis statistik <em>One Way Anova </em>menunjukkan bahwa terdapat perbedaan kadar LDL yang signifikan antara ketiga kelompok pada penelitian ini (p&lt;0,001). Kadar LDL pada K2 (=16,00±3,29) meningkat secara bermakna dibandingkan dengan K1 (=10,62±1,77). Sedangkan kadar LDL pada K3 (=6,88±2,42) menurun secara bermakna dibandingkan dengan K2. Dari hasil penelitian ini dapat disimpulkan bahwa ekstrak rumput laut merah (<em>Kappaphycus alvarezii</em>) berpengaruh terhadap kadar LDL darah pada tikus putih (<em>Rattus norvegicus</em>) jantan galur Wistar yang diberi diet tinggi lemak.</p><p><strong>Kata kunci</strong> : diet tinggi lemak, LDL, <em>Kappaphycus alvarezii</em></p>

Home ownership in Saudi Arabia: Spatial Dimensions

2018 ◽  
Author(s):  
Asharaf Abdul Salam
Keyword(s):  
Saudi Arabia ◽  
Standard Deviation ◽  
Detailed Analysis ◽  
Statistical Methods ◽  
Home Ownership ◽  
Ownership Type ◽  
Chi Square ◽  
Spatial Dimensions ◽  
One Way Anova

<p>This paper undertakes a detailed analysis of 2010 Census Population and Household Tables (Final), to assess governorate wise variations in home ownership, type of living accommodations and housing infrastructure - material used for construction, electricity, water and sewage facilities.</p> <p>The data published by the Ministry of Economics and Planning in its “Population and Housing, 2010 Census” analyzed in detail using SPSS20, applying statistical methods such as, cross tabulations and chi-square; mean and standard deviation; and One-Way ANOVA. Governorates classified into small, medium and large, according to the number of Saudi persons, have been analyzed across 13 regions quantifying homeownership status. Further governorates are classified according to the percentage of owning homes in order to analyze the type of living accommodations, built up material of housing, source of electricity, water and sewage facilities. </p> <br>

Home ownership in Saudi Arabia: Spatial Dimensions

2018 ◽  
Author(s):  
Asharaf Abdul Salam
Keyword(s):  
Saudi Arabia ◽  
Standard Deviation ◽  
Detailed Analysis ◽  
Statistical Methods ◽  
Home Ownership ◽  
Ownership Type ◽  
Chi Square ◽  
Spatial Dimensions ◽  
One Way Anova

<p>This paper undertakes a detailed analysis of 2010 Census Population and Household Tables (Final), to assess governorate wise variations in home ownership, type of living accommodations and housing infrastructure - material used for construction, electricity, water and sewage facilities.</p> <p>The data published by the Ministry of Economics and Planning in its “Population and Housing, 2010 Census” analyzed in detail using SPSS20, applying statistical methods such as, cross tabulations and chi-square; mean and standard deviation; and One-Way ANOVA. Governorates classified into small, medium and large, according to the number of Saudi persons, have been analyzed across 13 regions quantifying homeownership status. Further governorates are classified according to the percentage of owning homes in order to analyze the type of living accommodations, built up material of housing, source of electricity, water and sewage facilities. </p> <br>

Transplantation of coral fragment, Acropora formosa (Scleractinia)

2014 ◽  
pp. 1
Author(s):  
Hanny Tioho ◽  
Maykel A.J Karauwan
Keyword(s):  
Fragment Size ◽  
Observation Time ◽  
Minimum Size ◽  
Average Growth Rate ◽  
Average Growth ◽  
Significant Difference ◽  
Acropora Formosa ◽  
Survival And Growth ◽  
One Way Anova ◽  
Better Than

The minimum size of coral transplants, Acropora formosa, was assessed to support their survival and growth. For this, 150 coral fragments of different sizes (5, 10, 15 cm) were transplanted close to the donor colony. Their survivorship and growth were observed for 12 months. At the end of the observation time, 90% of 15 cm-transplanted coral fragments survived, while the others (10cm and 5 cm) did 86% and 82% respectively. The average growth rate of 5 cm-coral fragments was 0.860 cm/month, while 10 and 15 cm-fragments were 0.984 cm/month and 1.108 cm/month respectively. One-way ANOVA showed that there was significant difference (p<0.05) among the three (5, 10, 15 cm) transplant initial sizes in which the longest fragment size tended to survive longer than the smaller one.  However, the smaller transplants grew better than the bigger one, 10.318 cm/year (206%) for 5 cm-transplant, 11.803 cm/year (118%) for 10 cm-transplant, and 13.299 cm/year (89%) for 15 cm-transplant, respectively. Ukuran minimal fragmen karang Acropora formosa yang ditransplantasi diduga untuk mendukung ketahanan hidup dan pertumbuhannya. Untuk itu, 150 fragmen karang ditransplantasi ke lokasi yang berdekatan dengan koloni induknya.  Ketahanan hidup dan pertumbuhan semua fragmen karang yang ditransplantasi diamati selama 12 bulan.  Pada akhir pengamatan, 90% dari fragmen karang berukuran 15 cm yang ditransplantasi dapat bertahan hidup, sedangkan yang lainnya (ukuran 10 cm dan 5 cm) masing-masing sebesar 86% dan 82%.  Rata-rata laju pertumbuhan fragmen karang dengan ukuran awal 5 cm adalah 0,860 cm/bulan, sedangkan ukuran fragmen 10 dan 15 cm masing-masing adalah 0,984 cm/bulan and 1,108 cm/bulan. ANOVA satu arah menunjukkan adanya perbedaan yang nyata (p<0.05) antara ketiga ukuran fragmen yang berbeda, di mana ukuran fragmen karang yang lebih panjang cenderung mempunyai ketahanan hidup yang lebih baik. Namun demikian, ukuran transplant yang lebih kecil memiliki pertumbuhan lebih baik dibandingkan dengan ukuran yang lebih besar, yakni10,318 cm/tahun (206%) untuk transplant berukuran 5 cm, 11,803 cm/tahun (118%) untuk 10 cm, dan 13,299 cm/tahun (89%) untuk ukuran 15 cm.

Sign in / Sign up

Export Citation Format

Share Document