scholarly journals Entrepeneur Independence Model in Improving Entrepeneur's Performance in Lubuk Pakam District

2021 ◽  
Vol 2 (2) ◽  
Keyword(s):  
Independence Model

Relationship of Cognitive Style to Locus of Control

1973 ◽  
Vol 37 (2) ◽  
pp. 553-554 ◽  
Author(s):  
Walter G. McIntire ◽  
Albert S. Dreyer
Keyword(s):  
Locus Of Control ◽  
Field Independence ◽  
External Locus ◽  
Control Scale ◽  
Psychological Constructs ◽  
Independence Model ◽  
Embedded Figures Test ◽  
External Locus Of Control ◽  
Relationship Of ◽  
Psychological Dimensions

The extent to which the Rotter Internal-External Locus of Control model and the Witkin Field Dependence-Field Independence model were concerned with the same psychological dimensions was examined. Correlations between the Internal-External Locus of Control Scale and the Group Embedded-figures Test of .102 for 80 males and −.001 for 99 females were found. It was concluded that these are independent psychological constructs.

scholarly journals Farnesol increases the activity of echinocandins against Candida auris biofilms

2019 ◽  
Vol 58 (3) ◽  
pp. 404-407 ◽  
Author(s):  
Fruzsina Nagy ◽  
Zoltán Tóth ◽  
Lajos Daróczi ◽  
Adrien Székely ◽  
Andrew M Borman ◽  
...  
Keyword(s):  
Inhibitory Concentration ◽  
Candida Auris ◽  
Independence Model ◽  
Microscope Images ◽  
Vitro Effect ◽  
Volume Range ◽  
Quorum Sensing Molecule ◽  
Bliss Independence ◽  
Scanning Electron

Abstract Candida auris biofilms exhibit decreased susceptibility to echinocandins, which is associated with poorer clinical outcomes. Farnesol is a quorum-sensing molecule enhancing the activity of antifungals; therefore, we evaluated the in vitro effect of farnesol with anidulafungin, caspofungin, or micafungin against biofilms using fractional inhibitory concentration indexes (FICI), Bliss independence model, LIVE/DEAD-assay and scanning electron microscopy. Based on mathematical models, farnesol caused synergism in eleven out of twelve cases (FICIs range 0.133-0.507; Bliss synergy volume range 70.39–204.6 μM2%). This was confirmed by microscope images of combination-exposed biofilms. Our study showed the prominent effect of farnesol with echinocandins against C. auris biofilms.

Communal strength, exchange orientation, equity, and relational maintenance

2020 ◽  
Vol 37 (8-9) ◽  
pp. 2345-2365
Author(s):  
Laura Stafford
Keyword(s):  
Structural Equation ◽  
Equation Modeling ◽  
Relational Maintenance ◽  
Heterosexual Couples ◽  
Independence Model ◽  
Exchange Orientation ◽  
Maintenance Behaviors ◽  
Self Reports ◽  
Communal Orientation ◽  
Communal Strength

The purpose of this study was to explore communal strength (i.e., partner-specific communal orientation) and partner-specific exchange orientation, as well as equity, as predictors of relational maintenance. A sample of 309 heterosexual couples completed self-reports. Given the dyadic interdependence, the actor–partner independence model was used. Dyadic analyses were undertaken using structural equation modeling conducted in AMOS. Results indicated that underbenefitedness was a predictor of maintenance behaviors, but overbenefitedness was not. Communal strength was also associated with engagement in maintenance behaviors. Importantly, communal strength moderated the association between underbenefitedness and maintenance such that underbenefitedness did not result in decreases in self-reported maintenance behaviors for those with greater communal strength to the same extent as it did for those with lower communal strength. Exchange orientation also moderated the association between underbenefitedness and maintenance behaviors such that a decline in maintenance behaviors was not as pronounced for those with lower exchange orientations as those with higher exchange orientations. Findings suggest the important role relational orientations may play in enacting our relationships.

scholarly journals Combination of the Glutaminyl Cyclase Inhibitor PQ912 (Varoglutamstat) and the Murine Monoclonal Antibody PBD-C06 (m6) Shows Additive Effects on Brain Aβ Pathology in Transgenic Mice

2021 ◽  
Vol 22 (21) ◽  
pp. 11791
Author(s):  
Torsten Hoffmann ◽  
Jens-Ulrich Rahfeld ◽  
Mathias Schenk ◽  
Falk Ponath ◽  
Koki Makioka ◽  
...  
Keyword(s):  
Monoclonal Antibody ◽  
Transgenic Mice ◽  
Combination Index ◽  
Individual Compound ◽  
Additive Effects ◽  
Glutaminyl Cyclase ◽  
Independence Model ◽  
Mice Brain ◽  
The Individual ◽  
Bliss Independence

Compelling evidence suggests that pyroglutamate-modified Aβ (pGlu3-Aβ; AβN3pG) peptides play a pivotal role in the development and progression of Alzheimer’s disease (AD). Approaches targeting pGlu3-Aβ by glutaminyl cyclase (QC) inhibition (Varoglutamstat) or monoclonal antibodies (Donanemab) are currently in clinical development. Here, we aimed at an assessment of combination therapy of Varoglutamstat (PQ912) and a pGlu3-Aβ-specific antibody (m6) in transgenic mice. Whereas the single treatments at subtherapeutic doses show moderate (16–41%) but statistically insignificant reduction of Aβ42 and pGlu-Aβ42 in mice brain, the combination of both treatments resulted in significant reductions of Aβ by 45–65%. Evaluation of these data using the Bliss independence model revealed a combination index of ≈1, which is indicative for an additive effect of the compounds. The data are interpreted in terms of different pathways, in which the two drugs act. While PQ912 prevents the formation of pGlu3-Aβ in different compartments, the antibody is able to clear existing pGlu3-Aβ deposits. The results suggest that combination of the small molecule Varoglutamstat and a pE3Aβ-directed monoclonal antibody may allow a reduction of the individual compound doses while maintaining the therapeutic effect.

scholarly journals PENERAPAN MODEL KEMANDIRIAN AKTIF SECARA DARING UNTUK MENINGKATKAN AKTIVITAS DAN PENGUASAAN MATERI FENOMENA KUANTUM SISWA SMA NEGERI 2 BANDAR LAMPUNG TAHUN PELAJARAN 2020/2021

2021 ◽  
Vol 1 (3) ◽  
pp. 282-294
Author(s):  
ATO SUHARTO
Keyword(s):  
Qualitative Data ◽  
Scientific Work ◽  
Activity Data ◽  
Student Activities ◽  
Student Activity ◽  
Independence Model ◽  
The Third ◽  
Evaluation Scores ◽  
Quantum Phenomena ◽  
Student Observation

Lack of passion in studying Physics in this Covid-19 Pandemic era, resulted in less than optimal Physics learning outcomes, this is what moves the author to conduct research with the aim of; (1). Describing student activities in learning activities using an active independence model, (2). Describing students' mastery of quantum phenomena using an active independence model. The sample in this study, namely class XII MIPA-6 which has the characteristics; students' mastery of quantum phenomena is low, and students' activities are limited to sitting, taking notes, and listening. Data collection in this study was carried out using; (1). Student observation sheet, (2). Teacher observation sheet, (3). Group work sheets and presentation review sheets were carried out at each meeting, (4) independent task sheets were carried out in each cycle, and (5) evaluation tests were carried out at the end of each cycle. The data analyzed in this study consisted of; (1). Qualitative data, is data from observations consisting of student activity data and research teacher activity data, (2). Quantitative data, in the form of values ??taken from the group's scientific work, presentation review scores, independent assignment scores and end-of-cycle evaluation scores. Based on the research results obtained; (1). The increase in student activity in the first cycle of 80.56% increased to 86.11% in the second cycle and increased again to 91.67% in the third cycle, (2). The increase in students' mastery of quantum phenomena in the first cycle was 50.85 to 68.96 in the second cycle or 18.11% and increased in the third cycle to 80.84 or an increase of 11.88%. ABSTRAKKurangnya gairah dalam belajar Fisika pada era Pandemi Covid-19 ini, mengakibatkan hasil belajar Fisika yang kurang optimal, hal ini yang menggerakan penulis untuk melakukan penelitian dengan tujuan; (1). Mendeskripsikan aktivitas siswa dalam kegiatan pembelajaran menggunakan model kemandirian aktif, (2). Mendeskripsikan penguasaan siswa terhadap materi fenomena kuantum menggunakan model kemandirian aktif. Percontoh dalam penelitian ini, yakni kelas XII MIPA-6 yang mempunyai karakteristik; penguasaan materi fenomena kuantum siswa rendah, dan aktivitas siswa terbatas pada duduk, mencatat, dan mendengarkan. Pengambilan data pada penelitian ini dilakukan menggunakan; (1). Lembar observasi siswa, (2). Lembar observasi guru, (3). Lembar kerja kelompok dan lembar review presentasi yang dilakukan pada setiap pertemuan, (4) Lembar tugas mandiri yang dilakukan pada setiap siklusnya, dan (5) Tes evaluasi yang dilaksanakan pada setiap akhir siklus. Data yang dianalisis pada penelitian ini terdiri dari; (1). Data Kualitatif, merupakan data hasil observasi yang terdiri dari data aktivitas siswa dan data aktivitas guru peneliti, (2). Data Kuantitatif, berupa nilai yang diambil dari kerja ilmiah kelomok, nilai review presentasi, nilai tugas mandiri dan nilai evaluasi akhir siklus. Berdasarkan hasil penelitian diperoleh; (1). Peningkatan aktivitas siswa pada siklus I sebesar 80,56% meningkat menjadi 86,11% pada siklus II dan meningkat lagi menjadi 91,67% pada siklus III, (2). Peningkatan penguasaan materi fenomena kuantum siswa pada siklus I sebesar 50,85 menjadi 68,96 pada siklus II atau naik 18,11% dan meningkat pada siklus III menjadi 80,84 atau mengalami kenaikan sebesar 11,88%.

Reply to Henk van den Belt’s and Rick Benjamins’ articles : The resurrection and the subject philosophy

2020 ◽  
Vol 74 (2) ◽  
pp. 149-166
Author(s):  
Dirk-Martin Grube
Keyword(s):  
Independence Model ◽  
The Subject ◽  
The Way

Abstract In the first part, Dirk-Martin Grube follows Paul Tillich’s leads by suggesting that revelation consists primarily in knowledge of knowledge rather than knowledge of facts. Grube holds that the evidence for the resurrection is such that its historicity can neither be confirmed (against Henk van den Belt) nor denied. Rather, it should be considered to be logically undecidable. Different from Van den Belt, Grube follows Tillich by sympathizing with the independence model for relating religion to science. In the second part, Grube takes up the issue Rick Benjamins focusses on, subject philosophy. After delving into the different positions on the way in which Tillich has adopted this philosophy, Grube evaluates subject philosophy, partly deviating from Benjamins, partly agreeing with him.

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