scholarly journals Evaluation of Urinary Nuclear Matrix Protein as a New Marker for Urinary Bladder Cancer.

2000 ◽  
Vol 50 (3) ◽  
pp. 237-239
Author(s):  
Takanori Suzuki ◽  
Kouichi Suzuki ◽  
Hiroshi Okazaki ◽  
Yoshihiro Ono ◽  
Masashi Ozawa
Keyword(s):  
Bladder Cancer ◽  
Urinary Bladder ◽  
Nuclear Matrix ◽  
Matrix Protein ◽  
Urinary Bladder Cancer ◽  
Nuclear Matrix Protein

984: Variability in the Performance of Nuclear Matrix Protein 22 in the Detection of Bladder Cancer

2006 ◽  
Vol 175 (4S) ◽  
pp. 317-317
Author(s):  
Shahrokh F. Shariat ◽  
Michael Marberger ◽  
Yair Lotan ◽  
Marta Sanchez-Carbayo ◽  
Craig D. Zippe ◽  
...  
Keyword(s):  
Bladder Cancer ◽  
Nuclear Matrix ◽  
Matrix Protein ◽  
Nuclear Matrix Protein

Diagnostic accuracy of NMP-52, NMP-22 and urine cytology in the diagnosis of bladder cancer

2021 ◽  
Vol 16 (10) ◽  
pp. 59-62
Author(s):  
Mohamed J. Saadh
Keyword(s):  
Bladder Cancer ◽  
Nuclear Matrix ◽  
Diagnostic Performance ◽  
Matrix Protein ◽  
Urinary Cytology ◽  
Significant Relation ◽  
Nuclear Matrix Protein ◽  
Diagnostic Efficacy ◽  
Noninvasive Biomarkers ◽  
New Biomarkers

Bladder cancer (BC) is the most important tumor problem of urologic cancer. Therefore, noninvasive urinary biomarkers were used for diagnosis of BC. However, the new biomarkers failed to reach higher accuracy. The aim of this study was to assess the diagnostic efficacy of nuclear matrix protein-22 (NMP- 22), nuclear matrix protein-52 (NMP-52), urinary cytology and to investigate combinations of urine NMP-52 with urinary cytology as noninvasive biomarkers to increase diagnostic performance of bladder cancer at different grades and stages. Overall, there were 156 subjects (62 BC, 54 cystitis patients and 40 healthy volunteers). The NMP-22 and NMP-52 were quantified in urine samples by ELISA. The urinary cytology is used by some physicians routinely for diagnosis of BC. The sensitivity and specificity for NMP-52 were 94% and 82%, for NMP-22 69% and 80.8% and for cytology 56% and 94.6% respectively and also, both urinary NMP-22 and NMP-52 have extremely significant relation (p<0.0001) to BC vs. healthy individuals and cystitis patients. Moreover, the combination of NMP- 52 with urinary cytology could predict all BC stages and grade with 95.6% sensitivity and 94.3% specificity. In conclusion, NMP-52 and urinary cytology in combination improve diagnostic performance for BC detection in different pathological types.

An office-based immunodiagnostic assay for detecting urinary nuclear matrix protein 52 in patients with bladder cancer

2005 ◽  
Vol 96 (3) ◽  
pp. 334-339 ◽  
Author(s):  
Abdelfattah M. Attallah ◽  
Hanem A. Sakr ◽  
Hisham Ismail ◽  
El-Sayed K. Abdel-Hady ◽  
Ibrahim El-Dosoky
Keyword(s):  
Bladder Cancer ◽  
Nuclear Matrix ◽  
Matrix Protein ◽  
Nuclear Matrix Protein

C118 Nuclear matrix protein 22 urinary marker in diagnosing and follow up of urinary bladder tumors

2009 ◽  
Vol 8 (8) ◽  
pp. 696
Author(s):  
T. Smrkolj ◽  
M. Mihelic ◽  
A. Sedlar ◽  
I. Sterle ◽  
J. Osredkar ◽  
...  
Keyword(s):  
Urinary Bladder ◽  
Nuclear Matrix ◽  
Matrix Protein ◽  
Bladder Tumors ◽  
Nuclear Matrix Protein ◽  
Urinary Marker

Comparison of Cytology and Nuclear Matrix Protein 22 for the Detection and Follow-Up of Bladder Cancer

2001 ◽  
Vol 66 (2) ◽  
pp. 72-77 ◽  
Author(s):  
Sven Lahme ◽  
Karl-Horst Bichler ◽  
Gerhard Feil ◽  
Steffen Krause
Keyword(s):  
Bladder Cancer ◽  
Nuclear Matrix ◽  
Matrix Protein ◽  
Nuclear Matrix Protein
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