scholarly journals Improved rubidium atomic beam clock based on lamp-pumping and fluorescence-detection scheme

2011 ◽  
Vol 6 ◽  
Author(s):  
Y. H. Wang ◽  
J. Q. Huang ◽  
Y. Gu ◽  
S. Q. Liu ◽  
T. Q. Dong ◽  
...  
Keyword(s):  
Fluorescence Detection ◽  
Atomic Beam ◽  
Detection Scheme ◽  
Lamp Pumping

Optical MEMS-based fluorescence detection scheme with applications to capillary electrophoresis

1998 ◽  
Author(s):  
Kurt D. Kramer ◽  
Kwang Wook Oh ◽  
Chong H. Ahn ◽  
James J. Bao ◽  
Kenneth R. Wehmeyer
Keyword(s):  
Capillary Electrophoresis ◽  
Fluorescence Detection ◽  
Optical Mems ◽  
Detection Scheme

MICROFLUIDIC FLOW-THROUGH REACTOR WITH ELECTROCHEMICAL SENSOR ARRAY FOR REAL-TIME PCR

2009 ◽  
Vol 23 (03) ◽  
pp. 369-372
Author(s):  
HUEY-FANG TEH ◽  
NAVEEN RAMALINGAM ◽  
HAI-QING GONG ◽  
SWEE-NGIN TAN
Keyword(s):  
Real Time ◽  
Fluorescence Detection ◽  
Microelectrode Array ◽  
Dna Amplification ◽  
Active Species ◽  
Dna Intercalator ◽  
Detection Scheme ◽  
Microfluidic Flow ◽  
Pcr Products ◽  
Flow Through

We developed an integrated microfluidic flow-through EC-PCR (EC-PCR) microdevice for the concurrent DNA amplification, PCR products EC detection and PCR products quantification instead of the current available fluorescence detection scheme. The microfluidic flow-through EC-PCR microdevice was fabricated with the state-of-the-art microfabrication technology, by bonding a bottom glass substrate having a microelectrode array to a top glass cover having the microchannels made of PDMS material. Both the amplification of the target DNA sequence and the subsequent EC detection of the PCR products were carried out concurrently on the integrated device by real-time monitoring. The underlying principle of the microfluidic flow-through EC-PCR method was based on the changes of current signal of methylene blue (MB), which worked as an electrochemically active species DNA intercalator in the PCR mixture, during the amplification process at the extension phase. The results shown in this work indicated that the nucleic acid analysis could be performed in a fast thermal cycling and true real-time quantitative electrochemical detection. The signal variation trends of the EC detection and the fluorescence detection were the same in our verification measurements for both methods, which suggested that the EC detection method was feasible for this application.

A fluorescence detection scheme for ultra large molecules after gas phase separation

Talanta ◽  
2007 ◽  
Vol 71 (5) ◽  
pp. 2126-2128 ◽  
Author(s):  
J HE ◽  
W ZHONG ◽  
A TANG ◽  
X YAN ◽  
C LEWIS ◽  
...  
Keyword(s):  
Phase Separation ◽  
Gas Phase ◽  
Fluorescence Detection ◽  
Detection Scheme ◽  
Large Molecules ◽  
Gas Phase Separation
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