The Ecological Role of Sulfate-Reducing Bacteria in Anaerobic Degradation of a Long-Chain Fatty Acid.

1995 ◽  
Vol 18 (6) ◽  
pp. 499-510 ◽  
Author(s):  
Takashi YAMAGUCHI ◽  
Hideki HARADA ◽  
Kiyoshi MOMONOI ◽  
I-Cheng TSENG
Keyword(s):  
Fatty Acid ◽  
Anaerobic Degradation ◽  
Sulfate Reducing Bacteria ◽  
Chain Fatty Acid ◽  
Ecological Role ◽  
Long Chain Fatty Acid ◽  
Sulfate Reducing ◽  
Reducing Bacteria ◽  
Long Chain

scholarly journals Essential Role of ELOVL4 Protein in Very Long Chain Fatty Acid Synthesis and Retinal Function

2011 ◽  
Vol 287 (14) ◽  
pp. 11469-11480 ◽  
Author(s):  
Richard Harkewicz ◽  
Hongjun Du ◽  
Zongzhong Tong ◽  
Hisham Alkuraya ◽  
Matthew Bedell ◽  
...  
Keyword(s):  
Fatty Acid ◽  
Fatty Acid Synthesis ◽  
Essential Role ◽  
Acid Synthesis ◽  
Chain Fatty Acid ◽  
Retinal Function ◽  
Long Chain Fatty Acid ◽  
Long Chain

Flüchtige Inhaltsstoffe von Ambrosiakäfern (Coleoptera: Scolytidae), II / Volatile Substances from Ambrosia Beetles, II

1974 ◽  
Vol 29 (5-6) ◽  
pp. 246-247 ◽  
Author(s):  
W. Francke ◽  
K. Heyns
Keyword(s):  
Fatty Acid ◽  
Bark Beetles ◽  
Chain Fatty Acid ◽  
Fatty Acid Esters ◽  
Ambrosia Beetle ◽  
Long Chain Fatty Acid ◽  
Males And Females ◽  
Acid Esters ◽  
Long Chain

Methylmyristate and ethylpalmitate were identified from males and females of the ambrosia beetle Xyloterus domesticus L. The role of these compounds is discussed in connection with a brief survey concerning the occurrence of long-chain fatty-acid esters in other insects and in the phloem of softwood as attractants for bark beetles.

scholarly journals Nuclear Lipid Microdomains Regulate Daunorubicin Resistance in Hepatoma Cells

2018 ◽  
Vol 19 (11) ◽  
pp. 3424 ◽  
Author(s):  
Michela Codini ◽  
Carmela Conte ◽  
Samuela Cataldi ◽  
Cataldo Arcuri ◽  
Andrea Lazzarini ◽  
...  
Keyword(s):  
Drug Resistance ◽  
Fatty Acid ◽  
Cancer Progression ◽  
Chain Fatty Acid ◽  
Active Chromatin ◽  
Long Chain Fatty Acid ◽  
Lipid Microdomains ◽  
Neutral Sphingomyelinase ◽  
Long Chain

Daunorubicin is an anticancer drug, and cholesterol is involved in cancer progression, but their relationship has not been defined. In this study, we developed a novel experimental model that utilizes daunorubicin, cholesterol, and daunorubicin plus cholesterol in the same cells (H35) to search for the role of nuclear lipid microdomains, rich in cholesterol and sphingomyelin, in drug resistance. We find that the daunorubicin induces perturbation of nuclear lipid microdomains, localized in the inner nuclear membrane, where active chromatin is anchored. As changes of sphingomyelin species in nuclear lipid microdomains depend on neutral sphingomyelinase activity, we extended our studies to investigate whether the enzyme is modulated by daunorubicin. Indeed the drug stimulated the sphingomyelinase activity that induced reduction of saturated long chain fatty acid sphingomyelin species in nuclear lipid microdomains. Incubation of untreated-drug cells with high levels of cholesterol resulted in the inhibition of sphingomyelinase activity with increased saturated fatty acid sphingomyelin species. In daunodubicin-treated cells, incubation with cholesterol reversed the action of the drug by acting via neutral sphingomyelinase. In conclusion, we suggest that cholesterol and sphingomyelin-forming nuclear lipid microdomains are involved in the drug resistance.

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