scholarly journals Sustained viral response (SVR) in type C liver cirrhosis patients undergoing peginterferon α-2b/ribavirin combination therapy after partial splenic embolization

Kanzo ◽  
2011 ◽  
Vol 52 (1) ◽  
pp. 26-35
Author(s):  
Keisuke Shiina ◽  
Atsushi Naganuma ◽  
Tomofumi Takakusaki ◽  
Masashi Namikawa ◽  
Hiroki Tahara ◽  
...  
Keyword(s):  
Liver Cirrhosis ◽  
Combination Therapy ◽  
Sustained Viral Response ◽  
Partial Splenic Embolization ◽  
Viral Response ◽  
Splenic Embolization ◽  
Type C ◽  
Peginterferon Α

Partial splenic embolization in patients with liver cirrhosis and hepatocellular carcinoma: Effects on portal hemodynamics

1994 ◽  
Vol 1 (2) ◽  
pp. 172-175 ◽  
Author(s):  
Kazuhiro Yamashiro ◽  
Mitsuhiro Mukaiya ◽  
Hiromichi Kimura ◽  
Tadashi Katsuramaki ◽  
Kazuaki Sasaki ◽  
...  
Keyword(s):  
Hepatocellular Carcinoma ◽  
Liver Cirrhosis ◽  
Partial Splenic Embolization ◽  
Portal Hemodynamics ◽  
Splenic Embolization

631 THE EFFECT OF PARTIAL SPLENIC EMBOLIZATION FOR THROMBOCYTOPENIA IN LIVER CIRRHOSIS PATIENTS

2012 ◽  
Vol 56 ◽  
pp. S250 ◽  
Author(s):  
B.I. Kim ◽  
Y.K. Cho ◽  
H.J. Kim ◽  
J.H. Park ◽  
D.I. Park ◽  
...  
Keyword(s):  
Liver Cirrhosis ◽  
Partial Splenic Embolization ◽  
Splenic Embolization

Partial Splenic Embolization for Hypersplenism in Cirrhotic Patients. A Case Series

2014 ◽  
Vol 23 (2) ◽  
pp. 215-218 ◽  
Author(s):  
Secil Omer ◽  
Octavian Zara ◽  
Claudia Iacobescu ◽  
Ion Dina
Keyword(s):  
Liver Cirrhosis ◽  
Portal Hypertension ◽  
Interventional Procedure ◽  
Case Series ◽  
Favourable Outcome ◽  
High Morbidity ◽  
Severe Thrombocytopenia ◽  
Partial Splenic Embolization ◽  
Splenic Embolization ◽  
Prognosis Of Liver Cirrhosis

The prognosis of liver cirrhosis depends on the presence of its major complications as well as on other factors such as hypersplenism with thrombocytopenia. Partial splenic embolization is an effective interventional procedure performed in liver cirrhosis complicated with portal hypertension to improve the low platelet count. This technique represents an efficient alternative to splenectomy, which has major drawbacks and is associated with a high morbidity. We report a series of patients with liver cirrhosis and portal hypertension who presented with severe thrombocytopenia and were treated with partial splenic embolization eventually having a favourable outcome.

Risk factors for complications after partial splenic embolization for liver cirrhosis

2008 ◽  
Vol 95 (6) ◽  
pp. 744-750 ◽  
Author(s):  
H. Hayashi ◽  
T. Beppu ◽  
K. Okabe ◽  
T. Masuda ◽  
H. Okabe ◽  
...  
Keyword(s):  
Risk Factors ◽  
Liver Cirrhosis ◽  
Partial Splenic Embolization ◽  
Splenic Embolization

scholarly journals Host Immunological Effects of Partial Splenic Embolization in Patients with Liver Cirrhosis

2018 ◽  
Vol 2018 ◽  
pp. 1-8 ◽  
Author(s):  
Yasushi Matsukiyo ◽  
Hidenari Nagai ◽  
Teppei Matsui ◽  
Yoshinori Igarashi
Keyword(s):  
Liver Cirrhosis ◽  
Japanese Patients ◽  
Serum Levels ◽  
Treg Cells ◽  
Host Immunity ◽  
Th2 Cells ◽  
Partial Splenic Embolization ◽  
T Lymphocyte Subsets ◽  
Splenic Embolization ◽  
Significant Change

Purpose. Restoration of the balance between T lymphocyte subsets and between Th1/Th2 cytokines together with improvement of antitumor immunity has been reported after hepatosplenectomy in patients with liver cirrhosis (LC) and hepatocellular carcinoma (HCC). However, the detailed effects of partial splenic embolization (PSE) on host immunity are unknown. Accordingly, this study evaluated host immunity in patients with cirrhosis receiving PSE for thrombocytopenia.Methods. Twenty-three adult Japanese patients with cirrhosis and thrombocytopenia underwent PSE using straight coils at our hospital between 2010 and 2015. Blood samples were collected before PSE and 4 weeks after PSE.Results. The platelet counts were significantly higher 4 weeks after PSE compared with before PSE. The white blood cell count (neutrophils, lymphocytes, and monocytes) also increased significantly after PSE. Furthermore, Th1 cells and Th2 cells showed a significant increase at 4 weeks after PSE compared with before PSE, although there was no significant change of Treg cells. Moreover, serum levels of TNF-alpha, soluble TNF receptor I, and soluble Fas were significantly increased after PSE. There was no significant change of the Child-Pugh score.Conclusions. In patients with cirrhosis and thrombocytopenia, PSE not only promoted the recovery of leukopenia and thrombocytopenia but also induced activation of host immunity.

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