scholarly journals A study on microvascular alteration in the experimental rat liver cirrhosis. With special reference on the significance of the hepatic artery in the pseudolobular formation.

Kanzo ◽  
1991 ◽  
Vol 32 (7) ◽  
pp. 708-716 ◽  
Author(s):  
Makoto SAEGUSA ◽  
Kiyoharu WATANABE ◽  
Masahiko OKUDAIRA ◽  
Kohdo ISHII ◽  
Hisao SHIBATA
Keyword(s):  
Liver Cirrhosis ◽  
Special Reference ◽  
Hepatic Artery ◽  
Rat Liver

Studies on liver cirrhosis (III) special reference to muramidase activity in fibrous rat liver

1966 ◽  
Vol 1 (2) ◽  
pp. 60-60
Author(s):  
Y. Yoshitoshi ◽  
T. Oda ◽  
K. Ishii ◽  
H. Suzuki ◽  
H. Oka ◽  
...  
Keyword(s):  
Liver Cirrhosis ◽  
Special Reference ◽  
Rat Liver ◽  
Muramidase Activity

Comparison of Thy–1 expression in human liver cirrhosis and different models of rat liver injury

2006 ◽  
Vol 44 (01) ◽  
Author(s):  
T Mansuroglu ◽  
J Dudas ◽  
B Saile ◽  
D Batusic ◽  
G Ramadori
Keyword(s):  
Liver Cirrhosis ◽  
Liver Injury ◽  
Rat Liver ◽  
Human Liver ◽  
Human Liver Cirrhosis

scholarly journals Doppler ultrasound in liver cirrhosis: correlation of hepatic artery and portal vein measurements with model for end-stage liver disease score in Egypt

2020 ◽  
Vol 51 (1) ◽  
Author(s):  
Ahmed Abdelrahman Mohamed Baz ◽  
Rana Magdy Mohamed ◽  
Khaled Helmy El-kaffas
Keyword(s):  
Liver Cirrhosis ◽  
Liver Disease ◽  
Portal Vein ◽  
Hepatic Artery ◽  
Meld Score ◽  
Hepatic Decompensation ◽  
End Stage Liver Disease ◽  
Cirrhotic Patients ◽  
Us Findings ◽  
End Stage

Abstract Background Liver cirrhosis is a multi-etiological entity that alters the hepatic functions and vascularity by varying grades. Hereby, a cross-sectional study enrolling 100 cirrhotic patients (51 males and 49 females), who were diagnosed clinically and assessed by model for end-stage liver disease (MELD) score, then correlated to the hepatic Doppler parameters and ultrasound (US) findings of hepatic decompensation like ascites and splenomegaly. Results By Doppler and US, splenomegaly was evident in 49% of patients, while ascites was present in 44% of them. Increased hepatic artery velocity (HAV) was found in70% of cases, while 59% showed reduced portal vein velocity (PVV). There was a statistically significant correlation between HAV and MELD score (ρ = 0.000), but no significant correlation with either hepatic artery resistivity index (HARI) (ρ = 0.675) or PVV (ρ =0.266). Moreover, HAV had been correlated to splenomegaly (ρ = 0.000), whereas HARI (ρ = 0.137) and PVV (ρ = 0.241) did not significantly correlate. Also, ascites had correlated significantly to MELD score and HAV (ρ = 0.000), but neither HARI (ρ = 0.607) nor PVV (ρ = 0.143) was significantly correlated. Our results showed that HAV > 145 cm/s could confidently predict a high MELD score with 62.50% and 97.62 % sensitivity and specificity. Conclusion Doppler parameters of hepatic vessels (specifically HAV) in addition to the US findings of hepatic decompensation proved to be a non-invasive and cost-effective imaging tool for severity assessment in cirrhotic patients (scored by MELD); they could be used as additional prognostic parameters for improving the available treatment options and outcomes.

Thalidomide prevents rat liver cirrhosis via inhibition of oxidative stress

2006 ◽  
Vol 202 (11) ◽  
pp. 777-788 ◽  
Author(s):  
Peng Lv ◽  
He-Sheng Luo ◽  
Xiao-Ping Zhou ◽  
Shelley Chireyath Paul ◽  
Yan-Jv Xiao ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Liver Cirrhosis ◽  
Rat Liver

Comparative effect of nifedipine and S-adenosylmethionine, singly and in combination on experimental rat liver cirrhosis

Life Sciences ◽  
1993 ◽  
Vol 52 (20) ◽  
pp. PL217-PL220 ◽  
Author(s):  
Emilio Barrio ◽  
Carlos Cutrín ◽  
María J. Meniño ◽  
Eugenio Pérez-Becerra
Keyword(s):  
Liver Cirrhosis ◽  
Rat Liver ◽  
Comparative Effect

Gene therapy for rat liver cirrhosis by naked hepatocyte growth factor gene transffer into liver

2000 ◽  
Vol 118 (4) ◽  
pp. A1014
Author(s):  
Masaharu Takeuchi ◽  
Hiranari Kanemura ◽  
Takahiro Ueki ◽  
Kiyoshi Horiguchi ◽  
Yasukane Asano ◽  
...  
Keyword(s):  
Gene Therapy ◽  
Liver Cirrhosis ◽  
Growth Factor ◽  
Hepatocyte Growth Factor ◽  
Rat Liver ◽  
Factor Gene ◽  
Growth Factor Gene ◽  
Hepatocyte Growth
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