scholarly journals Advanced hepatocellular carcinoma with tumor thrombus in the right portal vein and multiple intra-hepatic metastasis - A case report of effective combined therapy with hepatic resection and transcatherter arterial embolization.

Kanzo ◽  
1986 ◽  
Vol 27 (3) ◽  
pp. 366-372 ◽  
Author(s):  
Shoji NAKAMORI ◽  
Shingi IMAOKA ◽  
Yo SASAKI ◽  
Hiroaki OHIGASHI ◽  
Osamu ISHIKAWA ◽  
...  
Keyword(s):  
Hepatocellular Carcinoma ◽  
Case Report ◽  
Portal Vein ◽  
Hepatic Resection ◽  
Hepatic Metastasis ◽  
Tumor Thrombus ◽  
Combined Therapy ◽  
Arterial Embolization ◽  
Advanced Hepatocellular Carcinoma ◽  
The Right

scholarly journals Hepatocellular carcinoma with tumor thrombus extends to the right atrium and portal vein: A case report

2020 ◽  
Vol 12 (11) ◽  
pp. 1128-1135
Author(s):  
Diego Gomez-Puerto ◽  
Oriol Mirallas ◽  
Judit Vidal-González ◽  
Victor Vargas
Keyword(s):  
Hepatocellular Carcinoma ◽  
Case Report ◽  
Portal Vein ◽  
Right Atrium ◽  
Tumor Thrombus ◽  
The Right

scholarly journals Successful Conversion Surgery for Massive Hepatocellular Carcinoma with Tumor Thrombus in Main Portal Vein after Treatment with Lenvatinib Combined with Toripalimab: A Case Report

2021 ◽  
Author(s):  
JingZhong OuYang ◽  
Yanzhao Zhou ◽  
Zhengzheng Wang ◽  
Qingjun Li ◽  
Jinxue Zhou
Keyword(s):  
Hepatocellular Carcinoma ◽  
Portal Vein ◽  
Tumor Thrombus ◽  
Inflammatory Cells ◽  
Complete Response ◽  
Advanced Hepatocellular Carcinoma ◽  
Main Portal Vein ◽  
Advanced Hcc ◽  
Dismal Prognosis ◽  
The Right

Abstract Background:Advanced hepatocellular carcinoma (HCC) with Portal vein invasion has an extremely dismal prognosis. We report a rare case of advanced HCC with portal vein tumor thrombus (PVTT). First, Lenvatinib(Len) combined with Toripalimab(Tor) was treated. The patient was successfully treated with radical surgical resection after the tumor thrombus shrank. Postoperative pathology showed complete response (CR).Case presentation:A 52-year-old male patient had a massive liver cancer in his right liver, and the tumor thrombus grew to the main portal vein. He passed 4 cycles of Len combined with Tor, the tumor shrank rapidly, the level of tumor markers dropped rapidly, The tumor thrombus was successfully confined from the main portal vein to the right branch of the portal vein. Therefore, the patient underwent a right hepatectomy and successfully removed a complete PVTT. Histopathological results showed that the primary tumor and tumor thrombus were only infiltrated by inflammatory cells, and there were no viable tumor cells.Conclusions:Len combined with Tor can be used as a preoperative neoadjuvant regimen for the treatment of advanced HCC with massive macrovascular invasion.

scholarly journals Transarterial Radioembolization Treatment of Advanced Hepatocellular Carcinoma Invading the Right Atrium

2021 ◽  
pp. 1-4
Author(s):  
Kabalane Yammine ◽  
◽  
Sarah Khalife ◽  
Keyword(s):  
Hepatocellular Carcinoma ◽  
Inferior Vena Cava ◽  
Right Atrium ◽  
Tumor Thrombus ◽  
Inferior Vena ◽  
Vena Cava ◽  
Treatment Strategies ◽  
Complete Response ◽  
Advanced Hepatocellular Carcinoma ◽  
The Right

Tumor thrombus infiltration of hepatocellular carcinoma (HCC) into the inferior vena cava and right atrium is rare and is associated with a poor prognosis due to the critical location of the tumor and the limited efficiency of the available treatment strategies. In this study, we report the case of a patient with advanced HCC and tumor thrombus in the inferior vena cava and right atrium who demonstrated complete response with mass retraction upon Yttrium-90 trans-arterial radioembolization (90Y- TARE) therapy. Throughout the 16 months follow-ups after the radioembolization, the patient was free of any complications, revealing no occurrence of radiation-induced pneumonitis or tumor recurrence.

Hepatic Resection for Hepatocellular Carcinoma with Tumor Thrombus in the Major Portal Vein

2015 ◽  
Vol 32 (6) ◽  
pp. 413-420 ◽  
Author(s):  
Hidenobu Kojima ◽  
Etsuro Hatano ◽  
Kojiro Taura ◽  
Satoru Seo ◽  
Kentaro Yasuchika ◽  
...  
Keyword(s):  
Hepatocellular Carcinoma ◽  
Portal Vein ◽  
Hepatic Resection ◽  
Tumor Thrombus ◽  
Disease Free Survival ◽  
Hepatic Arterial Infusion ◽  
Hazard Ratio ◽  
Infusion Chemotherapy ◽  
Independent Risk Factors ◽  
Tumor Thrombi

Background: The prognosis of hepatocellular carcinoma (HCC) with tumor thrombus in the major portal vein has been extremely poor. We investigated the outcome of hepatic resection in HCC with major portal vein tumor thrombus (PVTT). Methods: We retrospectively evaluated 52 consecutive patients who underwent hepatic resection for HCC with tumor thrombi in the first branch or trunk of the portal vein. Factors related to disease-free survival (DFS) and overall survival (OS) were analyzed. Results: The median DFS and OS times were 8.9 and 27.6 months for the whole cohort, respectively. Multiple tumors (hazard ratio 2.12; 95% CI 1.11-4.33; p = 0.023), positive surgical margins (hazard ratio 2.45; 95% CI 1.19-4.81; p = 0.016), and non-adjuvant hepatic arterial infusion chemotherapy (HAIC; hazard ratio 2.07; 95% CI 1.11-3.90; p = 0.023) were independent risk factors for DFS. Non-adjuvant HAIC (hazard ratio 1.84; 95% CI 1.01-3.37; p = 0.047) was an independent risk factor for OS. Conclusions: Macroscopically curative resection seems to be of benefit to HCC patients with PVTT, even with tumor thrombi in the first branch or trunk of the portal vein. Adjuvant postoperative HAIC might improve DFS and OS in such patients.

scholarly journals Cavo-atrial thrombectomy prior to hepatectomy for hepatocellular carcinoma with tumor thrombus in the right atrium: a case report

2019 ◽  
Vol 5 (1) ◽  
Author(s):  
Shun-ichi Ariizumi ◽  
Chizuo Kikuchi ◽  
Fumiaki Tokitou ◽  
Shingo Yamashita ◽  
Yoshihito Kotera ◽  
...  
Keyword(s):  
Hepatocellular Carcinoma ◽  
Case Report ◽  
Right Atrium ◽  
Tumor Thrombus ◽  
The Right

scholarly journals Hepatocellular Carcinoma With Tumor Thrombus Occupying the Right Atrium and Portal Vein

Medicine ◽  
2015 ◽  
Vol 94 (34) ◽  
pp. e1049 ◽  
Author(s):  
Xin Luo ◽  
Binhao Zhang ◽  
Shuilin Dong ◽  
Bixiang Zhang ◽  
Xiaoping Chen
Keyword(s):  
Hepatocellular Carcinoma ◽  
Portal Vein ◽  
Right Atrium ◽  
Tumor Thrombus ◽  
The Right
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