scholarly journals Measurement of portal vascular resistance in patients with chronic liver diseases by simultaneous measurement of portal blood flow and portal venous pressure.

Kanzo ◽  
1985 ◽  
Vol 26 (4) ◽  
pp. 485-492
Author(s):  
Fuminori MORIYASU ◽  
Osamu NISHIDA ◽  
Nobuyuki BAN ◽  
Takefumi NAKAMURA ◽  
Yasunari SOH ◽  
...  
Keyword(s):  
Blood Flow ◽  
Vascular Resistance ◽  
Simultaneous Measurement ◽  
Liver Diseases ◽  
Venous Pressure ◽  
Portal Blood Flow ◽  
Chronic Liver ◽  
Portal Blood ◽  
Portal Venous Pressure ◽  
Chronic Liver Diseases

scholarly journals HEMODYNAMICS IN THE BRANCHES OF THE AORTIC ARCHIN CHRONIC LIVER DISEASES

2015 ◽  
Vol 7 (1) ◽  
pp. 64-67
Author(s):  
V E Kulikov ◽  
T A Emelina ◽  
V A Kornilova ◽  
M A Toneva ◽  
E R Antonova
Keyword(s):  
Blood Flow ◽  
Hepatic Encephalopathy ◽  
Vascular Resistance ◽  
Liver Diseases ◽  
Hemispheric Asymmetry ◽  
Positive Relationship ◽  
Chronic Liver ◽  
Hemodynamic Parameters ◽  
Chronic Liver Diseases ◽  
Cerebral Hemodynamic

With cirrhosis of the liver statistically significant violations of cerebral hemodynamic parameters observed in intracranial department due to hemispheric asymmetry of blood flow. Hemispheric asymmetry of blood flow is marked by the development of vascular resistance and lability of the process of atherosclerosis. Hemispheric asymmetry between blood flow and stages of hepatic encephalopathy observed a noticeable positive relationship.

scholarly journals Effect of histamine H2-receptor antagonists on the total hepatic blood flow in patients with chronic liver diseases.

Kanzo ◽  
1986 ◽  
Vol 27 (7) ◽  
pp. 908-914 ◽  
Author(s):  
Kouichi AKAMATSU ◽  
Souichiro MIYAUCHI ◽  
Kenya MURASE ◽  
Yuji WATANABE ◽  
Nobuo NISHIMURA ◽  
...  
Keyword(s):  
Blood Flow ◽  
Hepatic Blood Flow ◽  
Liver Diseases ◽  
Chronic Liver ◽  
Chronic Liver Diseases ◽  
Receptor Antagonists ◽  
H2 Receptor Antagonists ◽  
Histamine H2 Receptor ◽  
H2 Receptor ◽  
Total Hepatic Blood Flow

scholarly journals Quantitative measurement of the portal blood flow in patients with various liver diseases using an ultrasonic duplex system.

Kanzo ◽  
1985 ◽  
Vol 26 (2) ◽  
pp. 208-214 ◽  
Author(s):  
Fuminori MORIYASU ◽  
Osamu NISHIDA ◽  
Nobuyuki BAN ◽  
Takefumi NAKAMURA ◽  
Masahiko SAKAI ◽  
...  
Keyword(s):  
Blood Flow ◽  
Liver Diseases ◽  
Quantitative Measurement ◽  
Portal Blood Flow ◽  
Portal Blood ◽  
Duplex System

Effects of Hct and norepinephrine on segmental vascular resistance distribution in isolated perfused rat livers

2004 ◽  
Vol 286 (1) ◽  
pp. H121-H130 ◽  
Author(s):  
Chiaki Kamikado ◽  
Toshishige Shibamoto ◽  
Minoru Hongo ◽  
Shozo Koyama
Keyword(s):  
Blood Flow ◽  
Vascular Resistance ◽  
Venous Pressure ◽  
Regression Line ◽  
Venous Occlusion ◽  
Portal Venous Pressure ◽  
Venous Resistance ◽  
Four Levels ◽  
Rat Livers ◽  
Line Analysis

We studied the effects of blood hematocrit (Hct), blood flow, or norepinephrine on segmental vascular resistances in isolated portally perfused rat livers. Total portal hepatic venous resistance ( Rt) was assigned to the portal ( Rpv), sinusoidal ( Rsinus), and hepatic venous ( Rhv) resistances using the portal occlusion (Ppo) and the hepatic venous occlusion (Phvo) pressures that were obtained during occlusion of the respective line. Four levels of Hct (30%, 20%, 10%, and 0%) were studied. Rpv comprises 44% of Rt, 37% of Rsinus, and 19% of Rhv in livers perfused at 30% Hct and portal venous pressure of 9.1 cmH2O. As Hct increased at a given blood flow, all three segmental vascular resistances of Rpv, Rsinus, and Rhv increased at flow >15 ml/min. As blood flow increased at a given Hct, only Rsinus increased without changes in Rpv or Rhv. Norepinephrine increased predominantly Rpv, and, to a smaller extent, Rsinus, but it did not affect Rhv. Finally, we estimated Ppo and Phvo from the double occlusion maneuver, which occluded simultaneously both the portal and hepatic venous lines. The regression line analysis revealed that Ppo and Phvo were identical with those measured by double occlusion. In conclusion, changes in blood Hct affect all three segmental vascular resistances, whereas changes in blood flow affect Rsinus, but not Rpv or Rhv. Norepinephrine increases mainly presinusoidal resistance. Ppo and Phvo can be obtained by the double occlusion method in isolated perfused rat livers.

Distensibility of portacaval shunts in portal hypertensive cats: index of contractility model

1994 ◽  
Vol 72 (6) ◽  
pp. 687-692
Author(s):  
Andrés C. Inglés ◽  
Dallas J. Legare ◽  
W. Wayne Lautt
Keyword(s):  
Blood Flow ◽  
Venous Pressure ◽  
Resistance Index ◽  
Portal Blood Flow ◽  
Portal Blood ◽  
Total Occlusion ◽  
Shunt Resistance ◽  
Wide Range ◽  
Flow Through ◽  
And Control

Complete shunting of portal blood flow through portacaval shunts was obtained using a constrictor around the portal vein to gradually produce a total occlusion. After 4 weeks, acute experiments were conducted in anesthetized cats. Blood from the femoral artery was shunted through a pump to supply and control the entire portal blood flow. As shunted portal blood flow was varied over a wide range, the portal shunt resistance showed distensibility. Decreasing portal venous pressure from 15.0 ± 0.9 to 11.1 ± 0.6 mmHg (1 mmHg = 133.3 Pa) resulted in elevations of resistance of 58%. The relation between the resistance (R) and the distending pressure (Pd) was a constant, the index of contractility (IC), where IC = R∙Pd3. In steady state, the IC was 485 ± 55 mmHg4∙mL−1∙min∙kg and did not change passively in response to changes in portal blood flow. In conclusion, portacaval shunts are passively distensible, and resistance is altered as a cubic function of the distending pressure. Because resistance is altered both actively and passively, the IC should prove useful to differentiate these alternatives for evaluation of changes in portal hypertensive therapy.Key words: portacaval shunts, distensibility model, vascular resistance, index of contractility.

Sign in / Sign up

Export Citation Format

Share Document