scholarly journals Evaluation of Antibiotic Resistance and β- lactamase Production in Clinical Isolates from a Tertiary Care Hospital in Central India

2018 ◽  
Vol 2 (1) ◽  
pp. 1-5
Author(s):  
Vaibhavi Vijay Nanoty ◽  
Gopal Nandlal Agrawal ◽  
Supriya Sanjay Tankhiwale ◽  
◽  
Keyword(s):  
Antibiotic Resistance ◽  
Tertiary Care Hospital ◽  
Tertiary Care ◽  
Central India ◽  
Clinical Isolates ◽  
Care Hospital

scholarly journals Current Pattern of Antibiotic Resistance in Clinical Isolates of Acinetobacter Baumannii from Intensive Care Units of Tertiary Care Hospital

2016 ◽  
Vol 22 (1) ◽  
pp. 17 ◽  
Author(s):  
Ishrat Irfan Ali ◽  
Irfan Ali Khan ◽  
Muhammad Kashif Munir ◽  
Sheikh Ajaz Rasool
Keyword(s):  
Antibiotic Resistance ◽  
Intensive Care ◽  
Acinetobacter Baumannii ◽  
Intensive Care Units ◽  
Tertiary Care Hospital ◽  
Tertiary Care ◽  
Clinical Isolates ◽  
Hospital Environment ◽  
Care Hospital ◽  
Acinetobacter Spp

<p><strong>Abstract</strong></p><p><strong>Purpose:  </strong>To determine the pattern of antibiotic resistance in clinical isolates of Acinetobacter baumannii from ICU’s of tertiary care hospital in Karachi.</p><p><strong>Study Design:  </strong>A case control study.</p><p><strong>Methods:  </strong>Three hundred and fifteen clinical isolates of Acinetobacter baumannii collected from different ICUs were evaluated during 1 year period. The isolates were identified by morphology, growth and biochemical characteristics, susceptibility to a panel of anti-microbial agents in disc diffusion assay and molecular characterization by PCR using glt A and gyr B genes.</p><p><strong>Results:  </strong>94% of Acinetobacter spp were detected as multi drug resistant (MDR) and sensitive to Polymixin B only. About 6% Acinetobacter spp were also MDR but sensitive to Polymixin B, Meropenem and Salbactum + Cefoperazone. All tested isolates exhibited differing resistance representation, as establish by medium incorporation – replica method, against different tested antibiotics, as follows: Amoxicillin – Cal-vulanic acid, Tazobactam, Ceftriaxone, Ceftazidime, Meropenem, Imipenem, Gentamicin, Amikacin, Chlo-ramphenicol, Cotrimoxazole, Tobramycin, Salbactam, Cefoperazone, Gentamicin and Amikacin. All the isolates of Acinetobacter baumannii were PCR positive for glt A and gyr B.</p><p><strong>Conclusions:  </strong>Acinetobacter baumannii is the most frequently isolated and alarming pathogen in the health care system specifically for the patients in intensive care units (ICUs). Its survival in hospital environment is because of tolerance the antibiotics and antiseptic pressures. Multi drug resistance made this pathogen the lethal pathogen of this century to infect debilitated patients. There is a strict need to monitor the surveillance of global clones at institutional and or intra-institutional level for accurate treatment, precise prevention and batter control.</p>

Sero-Prevalence of Parvovirus B 19 Infection Among HIV Positive Patients Attending Tertiary Care Hospital in Central India

2017 ◽  
Vol 01 (04) ◽  
pp. 127-132
Author(s):  
Bhushan Shrikhande ◽  
Meena Mishra ◽  
Mohiuddin Qazi ◽  
Arvind Kurhade ◽  
Chandrashekhar Unakal ◽  
...  
Keyword(s):  
Tertiary Care Hospital ◽  
Tertiary Care ◽  
Central India ◽  
Hiv Positive ◽  
Care Hospital ◽  
Parvovirus B 19
Sign in / Sign up

Export Citation Format

Share Document