scholarly journals Evaluation of Clinical Criteria for Performing Brain CT-Scan in Patients with Mild Traumatic Brain Injury; A New Diagnostic Probe

2019 ◽  
Vol 7 (3) ◽  
pp. 269-277
Author(s):  
Roghieh Molaei-Langroudi ◽  
Ahmad Alizadeh ◽  
Ehsan Kazemnejad-Leili ◽  
Vahid Monsef-Kasmaie ◽  
Seyed-Younes Moshirian
Keyword(s):  
Traumatic Brain Injury ◽  
Brain Injury ◽  
Ct Scan ◽  
Mild Traumatic Brain Injury ◽  
Clinical Criteria ◽  
Brain Ct ◽  
Diagnostic Probe ◽  
Brain Ct Scan

scholarly journals What are the strongest indicators of intracerebral hemorrhage in mild traumatic brain injury?

2021 ◽  
Vol 6 (1) ◽  
pp. e000717
Author(s):  
Panu Teeratakulpisarn ◽  
Phati Angkasith ◽  
Thanakorn Wannakul ◽  
Parichat Tanmit ◽  
Supatcha Prasertcharoensuk ◽  
...  
Keyword(s):  
Traumatic Brain Injury ◽  
Brain Injury ◽  
High Risk ◽  
Ct Scan ◽  
Mild Traumatic Brain Injury ◽  
Skull Fracture ◽  
Brain Ct ◽  
Baseline Characteristics ◽  
Gcs Score ◽  
The Brain

BackgroundAlthough there are eight factors known to indicate a high risk of intracranial hemorrhage (ICH) in mild traumatic brain injury (TBI), identification of the strongest of these factors may optimize the utility of brain CT in clinical practice. This study aimed to evaluate the predictors of ICH based on baseline characteristics/mode of injury, indications for brain CT, and a combination of both to determine the strongest indicator.MethodsThis was a descriptive, retrospective, analytical study. The inclusion criteria were diagnosis of mild TBI, high risk of ICH, and having undergone a CT scan of the brain. The outcome of the study was any type of ICH. Stepwise logistic regression analysis was used to find the strongest predictors according to three models: (1) injury pattern and baseline characteristics, (2) indications for CT scan of the brain, and (3) a combination of models 1 and 2.ResultsThere were 100 patients determined to be at risk of ICH based on indications for CT of the brain in patients with acute head injury. Of these, 24 (24.00%) had ICH. Model 1 found that injury due to motor vehicle crash was a significant predictor of ICH, with an adjusted OR (95% CI) of 11.53 (3.05 to 43.58). Models 2 and 3 showed Glasgow Coma Scale (GCS) score of 13 to 14 after 2 hours of observation and open skull or base of skull fracture to be independent predictors, with adjusted OR (95% CI) of 11.77 (1.32 to 104.96) and 5.88 (1.08 to 31.99) according to model 2.DiscussionOpen skull or base of skull fracture and GCS score of 13 to 14 after 2 hours of observation were the two strongest predictors of ICH in mild TBI.Level of evidenceIII.

scholarly journals Study protocol for investigating the performance of an automated blood test measuring GFAP and UCH-L1 in a prospective observational cohort of patients with mild traumatic brain injury: European BRAINI study

BMJ Open ◽  
2021 ◽  
Vol 11 (2) ◽  
pp. e043635
Author(s):  
Marion Richard ◽  
Alfonso Lagares ◽  
Victor Bondanese ◽  
Javier de la Cruz ◽  
Odile Mejan ◽  
...  
Keyword(s):  
Traumatic Brain Injury ◽  
Brain Injury ◽  
Ct Scan ◽  
Mild Traumatic Brain Injury ◽  
Brain Lesions ◽  
Ct Scans ◽  
Secondary Outcome ◽  
Serum Concentrations ◽  
Brain Ct ◽  
Automated Assay

IntroductionMild traumatic brain injury (mTBI) is a common cause of clinical consultation in the emergency department. Patients with mTBI may undergo brain CT scans based on clinical criteria. However, the proportion of patients with brain lesions on CT is very low. Two serum biomarkers, glial fibrillar acidic protein (GFAP) and ubiquitin carboxy-terminal hydrolase L1 (UCH-L1), have been shown to discriminate patients regarding the presence or absence of brain lesions on initial CT scan when assessed within the first 12 hours after TBI. However, the current technique for measuring serum concentrations of GFAP and UCH-L1 is manual and time consuming, which may hinder its use in routine clinical practice. This study assesses the diagnostic accuracy of an automated assay for the measurement of serum GFAP and UCH-L1 in a cohort of patients with mTBI who received a CT scan as the standard of care.Methods and analysisThis is a prospective multicentre observational study of 1760 patients with mTBI recruited in France and Spain across 16 participating sites. Adult patients with an initial Glasgow Coma Scale score of 13–15 and a brain CT scan underwent blood sampling within 12 hours after TBI. The primary outcome measure is the diagnostic performance of an automated assay measuring serum concentrations of GFAP and UCH-L1 for discriminating between patients with positive and negative findings on brain CT-scans. Secondary outcome measures include the performance of these two biomarkers in predicting the neurological status and quality of life at 1 week and 3 months after the trauma.Ethics and disseminationEthics approval was obtained by the Institutional Review Board of Sud-Ouest Outre Mer III in France (Re#2019-A01525-52) and Hospital 12 de Octubre in Spain (Re#19/322). The results will be presented at scientific meetings and published in peer-reviewed publications.Trial registration numberClinicalTrials.gov: NCT04032509.

scholarly journals Epidemiological, Clinical and Radiological Characteristics of Patients with Head Trauma

2017 ◽  
Vol 2 (1) ◽  
pp. 7
Author(s):  
Amir Moghadamahmadi ◽  
Alireza Vakilian ◽  
Habib Farahmand ◽  
Athena Sharifi-Razav ◽  
Farzad Tajik ◽  
...  
Keyword(s):  
Traumatic Brain Injury ◽  
Brain Injury ◽  
Head Injury ◽  
Ct Scan ◽  
Head Trauma ◽  
Clinical Symptoms ◽  
Head Injuries ◽  
Major Public Health Problem ◽  
Brain Ct ◽  
Brain Ct Scan

Introduction: Head injury has been recognized as a major public health problem and is a frequent cause of death and disability in young people and makes considerable demands on health services. Motor vehicle accidents are the major causes of traumatic brain injury (TBI) that its occurrence has been increasing in our country in recent years.Objective: We decided to study head injury in our region to evaluate the Epidemiological, clinical and radiological features of this health problem.Materials and methods: We reviewed 200 TBI-patients records in Ali ebn abitaleb hospital of Rafsanjan from November 2012 – September 2013. A Questionnaire including Age, Sex, Job, Cause of trauma, GCS, Brain CT Scan findings and clinical symptoms for every head trauma patient; was completed. Data were analyzed by SPSS software. We used Chi-square test and P-Value less than 0.05 was considered significant.Results: From the total of 200 patients, 73.5% were males and 26.5% were females. The most common age group was 20-24 years. Majority of patients were students. Traffic accidents were the major cause of injuries (64.5%) and 35.5% of them were motorcyclist. The most frequent finding of Brain CT scan was skull fracture and subdural hematoma. 25% of patient had severe head injury. In clinical symptoms in conscious patients, headache, nausea, vomiting and vertigo was common.Conclusion: This study showed that we should pay more attention to traumatic brain injury young patients who are the most active potential forces of our society. Traffic accident s are the major reason for head injuries. Pay attention to prevention of this accident can perform important role in decreasing of head injuries.

scholarly journals Findings of brain computed tomography scan in motorcyclist patients with head trauma referred to Shiraz Shahid Rajaei Trauma Center in summer 2016

2021 ◽  
pp. 75-85
Keyword(s):  
Computed Tomography ◽  
Traumatic Brain Injury ◽  
Brain Injury ◽  
Ct Scan ◽  
Incidental Findings ◽  
Ct Scans ◽  
Acute Trauma ◽  
Brain Computed Tomography ◽  
Brain Ct ◽  
Brain Ct Scan

Background: Head trauma and subsequent traumatic brain injury are among the main causes of morbidity and mortality in Iran. The present study aimed to assess the abnormal findings of brain computed tomography (CT) scan in motorcyclist patients with traumatic brain injury. Materials and Methods: This retrospective cross-sectional study (July-September 2016) was conducted on all motorcyclist patients over 12 years who were referred for brain CT scan to the Emergency Department of Shahid Rajaei Hospital in Shiraz. Patients' archived medical files were reviewed, and a data collection form including age, gender, and findings related to acute trauma and incidental findings were completed. The obtained data were then statistically analyzed. Results: A total of 642 patients were enrolled. The mean age score of participants was reported as 33.61±17.12 years. All patients were male. A number of 51 (7.9%) patients had abnormal findings in their brain CT scans. The most-reported findings were skull-based (23%) and cranial linear (17%) fractures. No incidental findings (findings unrelated to acute trauma) were found. Moreover, 8 (15.7%) patients died with abnormal findings in their brain CT scans. Conclusion: Since in the present study, only 7.9% of the patients had abnormal findings in their brain CT scan and considering the comparison of the results of this research with those obtained in other similar studies, brain CT scan is highly used in this center.

Evaluating mild traumatic brain injury management at a regional emergency department

2018 ◽  
Vol 24 (5) ◽  
pp. 390-394
Author(s):  
Ashlee Maree Brown ◽  
Dara M Twomey ◽  
Anna Wong Shee
Keyword(s):  
Traumatic Brain Injury ◽  
Brain Injury ◽  
Ct Scan ◽  
Mild Traumatic Brain Injury ◽  
Best Practice ◽  
Medical Service ◽  
Regional Health ◽  
Diagnosis Codes ◽  
Retrospective Audit ◽  
Concussive Injury

BackgroundEmergency departments (EDs) are usually the first point of contact, and often the only medical service available, for patients with mild traumatic brain injury (mTBI) in rural and regional areas. Clinical practice guidelines (CPGs) have been created to ensure best practice management of mTBI in EDs. Adherence to mTBI CPGs has rarely been evaluated in rural and regional areas.AimThe aim of this paper was to assess a regional health service’s adherence to their mTBI CPG.MethodsThis was a 12-month retrospective audit of 1280 ED records of patients ≥16 years presenting with mTBI to a regional Australian ED. Case selection used the Victorian Admitted Episodes Dataset codes for suspected head injury: principal diagnosis codes (S00-T98), concussive injury recorded in diagnosis codes (S06.00-S06.05) and unintentional external cause code (V00-X59). The data were collected to determine 4-hour observation rates, CT scan rates, safe discharge and appropriate referral documentation.ResultsFewer people received a CT scan than qualified (n=245, 65.3%), only 45% had 4-hour observations recorded, safe discharge was documented in 74.1% of cases and 33% received educational resources.Discussion/conclusionSeveral key elements for the management of mTBI were under-recorded, particularly 4-hour observations, safe discharge and education. Acquired brain injury clinic referrals were received in overwhelmingly fewer cases than had a CT scan (n=19, 6.3%). Overall, this study suggests that the regional health service does not currently fully adhere to the CPG and that the referral services are potentially underutilised.

Patients with mild traumatic brain injury: Immediate and long-term outcome compared to intra-cranial injuries on CT scan

Brain Injury ◽  
2006 ◽  
Vol 20 (11) ◽  
pp. 1131-1137 ◽  
Author(s):  
Charlotte Sadowski-Cron ◽  
Jörg Schneider ◽  
Pascal Senn ◽  
Bogdan P. Radanov ◽  
Pietro Ballinari ◽  
...  
Keyword(s):  
Traumatic Brain Injury ◽  
Brain Injury ◽  
Ct Scan ◽  
Mild Traumatic Brain Injury ◽  
Term Outcome ◽  
Long Term Outcome
Sign in / Sign up

Export Citation Format

Share Document