Vibigaba (germinated brown rice) and maintenance of normal blood pressure: evaluation of a health claim pursuant to Article 13(5) of Regulation (EC) No 1924/2006

Purpose. To study the dynamics of blood pressure (BP) indicators under the influence of exogenously administered melatonin (Melatonin-SZ, Severnaya Zvezda, Russia) with various manifestations of desynchronosis of circadian BP rhythms (arterial hypertension – AH, high normal blood pressure) to determine the scheme of their effective compensation. Material and methods. The study included 101 patients with desynchronosis of circadian rhythms of blood pressure – 52 patients with hypertension, constituting the first and second groups, and 49 individuals with high normal blood pressure, representing the third and fourth groups. Patients of the second and fourth groups received conservative therapy, patients of the first and third groups combined it with melatonin. All patients underwent measurements of office blood pressure, home monitoring of blood pressure (ABPM), electrocardiography, 24-hour blood pressure monitoring (ABPM). Results and discussion. In patients of the first and third groups, compared with the traditional treatment groups, by the end of the observation period, a significantly (p < 0.05) decrease in office systolic blood pressure (SBP) / diastolic blood pressure (DBP) was established: in the first group compared with the second – 1.11 / 1.13 times, in the third group compared to the fourth – 1.43 / 1.58 times; significantly more (p < 0.05) pronounced decrease in SBP / DBP during DMAD – by 1.08 / 1.17 and 1.58 / 1.62 times, respectively, Significantly (p < 0.05) more pronounced decrease in average daily, average daily and average nighttime SBP / DBP during ABPM – by 1.13 / 1.20, 1.11 / 1.20, 1.23 / 1.25 and 1.47 / 1.31, 1.42 / 1.19, 1.54 / 1.41 times, respectively; reliably (p < 0.05) more frequent registration of the dipper rhythm type SBP / DBP – 1.6 / 1.4 and 1.6 / 1.4 times, respectively. In addition, the dynamics of patients in the first and third groups showed a significant (p < 0.05) decrease in the mean daily and mean nighttime SBP / DBP variability (SBP in the first group by 27.3 and 41.3 %, respectively; DBP in the first group by 20.1 and 26.3 %, respectively; SBP in the third group by 13.5 and 25.2 %, respectively; DBP in the third group by 12.2 and 28.2 %, respectively). Conclusions. With various manifestations of desynchronosis of circadian rhythms of blood pressure (AH, high normal blood pressure), the prescription of melatonin (Melatonin-SZ, Severnaya Zvezda, Russia) at a dose of 3 mg per day 30–40 minutes before bedtime for a month against the background of non-drug therapy and antihypertensive drugs led to a significantly more effective decrease in blood pressure at its office measurement, DMAD, ABPM with an improvement in the circadian rhythm of blood pressure and normalization of blood pressure variability.

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Posterior reversible encephalopathy syndrome (PRES) in the course of immunosuppressive therapy in A 45-year-old male with normal blood pressure – case study

Polish Annals of Medicine ◽

10.29089/2017.17.00005 ◽

2018 ◽

Author(s):

Rakesh Jalali ◽

◽

Izabela Godlewska ◽

Grzegorz Dałek ◽

Justyna Chormańska ◽

...

Keyword(s):

Blood Pressure ◽

Immunosuppressive Therapy ◽

Posterior Reversible Encephalopathy Syndrome ◽

Normal Blood ◽

Normal Blood Pressure ◽

Posterior Reversible Encephalopathy ◽

Reversible Encephalopathy

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EFFECT OF SUBMAXIMAL EXERCISE ON SYSTOLIC AND DIASTOLIC BLOOD PRESSURE IN YOUNG SEDENTARY NORMOTENSIVE NEPALESE MEDICAL STUDENTS

Journal of Nepal Medical Association ◽

10.31729/jnma.658 ◽

2003 ◽

Vol 42 (149) ◽

pp. 315-6

Author(s):

Arijit Ghosh ◽

T Pramanik

Keyword(s):

Blood Pressure ◽

Medical Students ◽

Diastolic Blood Pressure ◽

Submaximal Exercise ◽

Muscular Exercise ◽

Normal Blood ◽

Normal Blood Pressure ◽

Standing Posture ◽

Normal Range ◽

Exercise Blood Pressure

Higher exercise blood pressure represents low cardiorespiratory status of an individual and vice versa. Thechanges in systolic and diastolic blood pressure in response to rhythmic isotonic muscular exercise in sedentaryyoung normotensive Nepalese students were assessed. Normal blood pressure in standing posture in maleand female subjects are about 115 / 75 mm of Hg. and 106 / 71 mm of Hg. respectively. Just after the exercisesystolic blood pressure increases moderately in both the sexes, whereas diastolic blood pressure remainsunchanged in most of the females. Diastolic blood pressure is found to be decreased slightly in the males,just after exercise. The present study indicates the cardiorespiratory status of the Napalese medical studentsis within normal range.

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