Vitamin C and contribution to the normal function of the immune system: evaluation of a health claim pursuant to Article 14 of Regulation (EC) No 1924/2006

The benefits of natural honeybee products (e.g., honey, royal jelly, beeswax, propolis, beevenom and pollen) to the immune system are remarkable, and many of them are involved in the induction of antibody production, maturation of immune cells and stimulation of the immune system. The type of plants in the geographical area, climatic conditions and production method have a significantly influence on the nutritional quality of honey. However, this variability can influence consumer liking by the sensory attributes of the product. The aim of this work was to compare the most popular honeys from Poland in terms of nutritional value, organoleptic properties and antioxidant activity. In the study, five varieties of honey (honeydew, forest, buckwheat, linden and dandelion) from conventional and organic production methods were tested. The nutritional characteristics of honey samples included acidity, content of water, sugars, vitamin C, HMF and phenolics (total and flavonoids), while honey color, taste, aroma and consistency were investigated in the organoleptic characteristics. The antioxidant activity was determined in water- and ethanol-soluble honey extracts using DPPH and ORAC tests. The results showed that organoleptic and nutritional characteristics of popular Polish honeys differ significantly in relation to plant source and production method. The significant effect of honey variety on the content of HMF, saccharose and phenolics, as well as acidity and antioxidant capacity were noted. The impact of variety and variety × production method interaction was significant in the case of the content of vitamin C, glucose and fructose. A visible difference of buckwheat and forest honeys from other samples was observed. The highest content of total phenolics with antioxidant activity based on the SET mechanism was found in buckwheat honeys, while forest honeys were richer in flavonoids.

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TINOSPORA CORDIFOLIA: A MAGICAL WAND WITH IMMENSE MEDICINAL APPLICATIONS

PLANT ARCHIVES ◽

10.51470/plantarchives.2021.v21.no2.024 ◽

2021 ◽

Vol 21 (2) ◽

Author(s):

Akanksha Arora

Keyword(s):

Immune System ◽

Vitamin C ◽

Health Benefits ◽

Tinospora Cordifolia ◽

C Protein ◽

Bioactive Phytochemicals ◽

Anti Inflammatory ◽

Significant Health ◽

Hiv Aids

Tinospora cordifolia, a herb with a potential of boosting the immune system of a person is fully packed with nutrition be it carbohydrates, vitamin C, protein, fat, bioactive phytochemicals etc which one can have for relieving the person from illness and providing significant health benefits. When it comes to healthy herbs and plants Tinospora cordifolia never fails as a choice to cure the diseases and the symptoms associated with it. It helps in the treatment and management of diabetes, cancer, HIV-AIDS, toxicity from aflatoxins, osteoporosis, inflammation, leprosy, arthritis etc by the helps of various phytochemicals present in it. Alkaloids like Tinocordiside, Palmatine, Magnoflorine helps in cancer, syringin works as a great anti-allergen, magnoflorine as an anti-inflammatory etc.

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PENENTUAN KADAR VITAMIN C BEBERAPA JENIS CABAI (Capsicum sp.) DENGAN SPEKTROFOTOMETRI UV-VIS

Jurnal Kimia Riset ◽

10.20473/jkr.v3i1.8874 ◽

2018 ◽

Vol 3 (1) ◽

pp. 1

Author(s):

Lilis Rosmainar Tambunan ◽

Widia Ningsih ◽

Ni Putu Ayu ◽

Haula Nanda

Keyword(s):

Free Radicals ◽

Immune System ◽

Vitamin C ◽

Oxidative Damage ◽

Spectrophotometric Method ◽

Fruits And Vegetables ◽

Preliminary Test ◽

The Body ◽

Red Pepper ◽

Pepper Sample

Vitamin C is one of the nutrients that act as antioxidants and effectively overcome free radicals that can damage cells or tissues, including protecting the lens from oxidative damage caused by radiation. Vitamin C is widely found in fruits, and vegetables, one of them in chili. Vitamin C in chili has a function as a good antioxidant for the body (able to increase the immune system absorbed by calcium in the body. This study aims to determine the levels of vitamin C contained in some types of chili using UV-Vis spectrophotometry method and conduct a preliminary test. The highest levels of vitamin C obtained by using spectrophotometric method at 200 nm wavelength were on red curly pepper (50 g/100 g) and followed by chili jablay orange-red (38 g/100 g), green cayenne (29 g/100 g), red pepper large (22 g/100 g), and large green chili (9 g/100 g). While based on preliminary test it was found that all chilies contain saponins, as well as only large red pepper (sample 1) and red curly pepper (sample 4) containing flavonoids Keywords: capsicum, chilly, spectrophotometry

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High-dose vitamin C enhances cancer immunotherapy

Science Translational Medicine ◽

10.1126/scitranslmed.aay8707 ◽

2020 ◽

Vol 12 (532) ◽

pp. eaay8707 ◽

Cited By ~ 17

Author(s):

Alessandro Magrì ◽

Giovanni Germano ◽

Annalisa Lorenzato ◽

Simona Lamba ◽

Rosaria Chilà ◽

...

Keyword(s):

Immune System ◽

Vitamin C ◽

Clinical Evidence ◽

High Dose ◽

Dependent Manner ◽

Cancer Cell Growth ◽

Mutational Burden ◽

Cancer Types ◽

High Doses ◽

High Dose Vitamin

Vitamin C (VitC) is known to directly impair cancer cell growth in preclinical models, but there is little clinical evidence on its antitumoral efficacy. In addition, whether and how VitC modulates anticancer immune responses is mostly unknown. Here, we show that a fully competent immune system is required to maximize the antiproliferative effect of VitC in breast, colorectal, melanoma, and pancreatic murine tumors. High-dose VitC modulates infiltration of the tumor microenvironment by cells of the immune system and delays cancer growth in a T cell–dependent manner. VitC not only enhances the cytotoxic activity of adoptively transferred CD8 T cells but also cooperates with immune checkpoint therapy (ICT) in several cancer types. Combination of VitC and ICT can be curative in models of mismatch repair–deficient tumors with high mutational burden. This work provides a rationale for clinical trials combining ICT with high doses of VitC.

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