scholarly journals Alopecia Fibrosante em Padrão de Distribuição Androgenética: Patogénese, Diagnóstico e Tratamento

2020 ◽  
Vol 78 (3) ◽  
pp. 245-249
Author(s):  
Ana Marcos-Pinto ◽  
G. De Caprio ◽  
R. Oliveira Soares
Keyword(s):  
Hair Loss ◽  
Early Treatment ◽  
Inflammatory Infiltrate ◽  
Androgenetic Alopecia ◽  
Lichen Planopilaris ◽  
Scarring Alopecia ◽  
Area Loss ◽  
Pattern Distribution

Fibrosing alopecia in a pattern distribution is a recently recognized type of scarring alopecia, with hair loss in androgens- dependent area. Loss of follicular openings, perifollicular erythema, perifollicular hyperkeratosis and anisotriquia are the trichoscopic clues and follicular lichenoid inflammatory infiltrate the important finding in histopathology. It shares features of androgenetic alopecia and lichen planopilaris. Dermatologists should be familiarized with this entity in order to optimize the diagnosis and provide early treatment to prevent irreversible follicular damage.

Break Dancing: A New Risk Factor for Scarring Hair Loss

2011 ◽  
Vol 15 (3) ◽  
pp. 177-179 ◽  
Author(s):  
Assaf Monselise ◽  
Lisa J.Y. Chan ◽  
Jerry Shapiro
Keyword(s):  
Risk Factor ◽  
Hair Loss ◽  
Early Recognition ◽  
Androgenetic Alopecia ◽  
Treatment Modalities ◽  
Lichen Planopilaris ◽  
First Case ◽  
Appropriate Treatment ◽  
Scalp Biopsy

Background: We report on a first case of lichen planopilaris (LPP) mimicking androgenetic alopecia (AGA) in an individual who has been break-dancing on his head for many years. LPP is an autoimmune inflammatory scalp condition that when left untreated can result in scarring and irreversible hair loss. The etiology of LPP is unknown. Different treatment modalities are used for LPP and AGA. Objective: To increase the awareness of physicians to the possibility of scarring hair loss (LPP) presenting like AGA. Results: Scalp examination showed scarring patches of hair loss. A scalp biopsy confirmed the diagnosis of LPP. Conclusion: Chronic scalp trauma due to break dancing may be a trigger for LPP. A meticulous scalp examination should be performed before making a diagnosis of nonscarring conditions of hair loss such as AGA. Early recognition of LPP and appropriate treatment are important before scarring and irreversible hair loss ensue.

scholarly journals Changes in the hair growth cycle in women with non-scarring alopecia

2019 ◽  
Vol 94 (5) ◽  
pp. 39-49
Author(s):  
A. A. Kubanov ◽  
Y. A. Gallyamova ◽  
O. A. Korableva
Keyword(s):  
Growth Factors ◽  
Growth Factor ◽  
Hair Loss ◽  
Reference Group ◽  
Growth Cycle ◽  
Punch Biopsy ◽  
Androgenetic Alopecia ◽  
Pharmacological Agents ◽  
Scarring Alopecia ◽  
Cycle Growth

One of the key elements in the pathophysiological process of androgenetic alopecia and telogen hair loss is the change of hair cycle. Growth factors controlling the development and cycle of the hair follicle have thus far been established. However, the role of growth factors in the pathogenesis of alopecia remains to be revealed.Objective.This study was aimed at investigating the expression of the VEGF, KGF, EGF and TGF-01 growth factors in women with androgenetic alopecia and telogen hair loss, as well as their role in the development of alopecia.Materials and methods. 60 female patients diagnosed with telogen hair loss (30 women) and androgenetic alopecia (30 women) were observed. In order to investigate the expression of the VEGF, KGF, EGF and TGF-01 growth factors, we conducted an immunofluorescent analysis of skin samples obtained by punch biopsy (4 mm) from the frontoparietal scalp area of patients with androgenetic alopecia and telogen hair loss. 15 samples obtained from healthy people were used as a reference group.Results.A change in the expression of the VEGF, KGF and TGF-01 growth factors in women with androgenetic alopecia and telogen hair loss was established in comparison with healthy individuals. A correlation was found between the expression of the growth factors under study, age (p ≤ 0.05), as well as the character and duration of the disease (p ≤ 0.05) in women with non-scarring alopecia. The expression of the growth factors is found to be dependent on the clinical form of alopecia (p < 0.001).Conclusion.The VEGF growth factor is established to have the most significant effect on the development of androgenetic alopecia in women, with the KGF, TGF-01 and EGF factors being less significant as the predictors of this disorder. The VEGF growth factor is shown to affect telogen hair loss to a greater extent compared to the EGF factor. Our study confirms differences in the pathogenesis of androgenetic alopecia and telogen hair loss in women. The findings suggest that the VEGF and KGF growth factors, as well as TGF-01 inhibitors may be used as potential pharmacological agents for treating patients suffering from androgenetic alopecia and telogen hair loss.

scholarly journals Hair transplantation in androgenetic alopecia

2021 ◽  
Vol 1 ◽  
pp. 20
Author(s):  
Kavish Chouhan ◽  
Gillian Roga
Keyword(s):  
Medical Therapy ◽  
Hair Loss ◽  
Androgenetic Alopecia ◽  
Hair Transplantation ◽  
Common Cause ◽  
The Past ◽  
Scarring Alopecia ◽  
Male Pattern

Androgenetic alopecia is the most common cause of non-scarring alopecia in men. Even though the past couple of years have seen significant advancements in the management of patterned hair loss. Medical therapy as a standalone treatment remains unsatisfactory and surgical restoration of hair has found to be extremely gratifying as far as male pattern hair loss is concerned. In this article, we will review the latest developments in the field of hair transplantation undertaken in androgenetic alopecia.

scholarly journals Fibrosing Alopecia in a Pattern Distribution: A Case Report and Literature Review

2019 ◽  
Vol 11 (3) ◽  
pp. 297-302
Author(s):  
Korn Triyangkulsri ◽  
Ploychompoo Srisuwanwattana ◽  
Tueboon Sriphojanart ◽  
Poonkiat Suchonwanit
Keyword(s):  
Case Report ◽  
Postmenopausal Woman ◽  
Literature Review ◽  
Hair Loss ◽  
Case Reports ◽  
Lichen Planopilaris ◽  
The Family ◽  
Pattern Distribution

Fibrosing alopecia in a pattern distribution (FAPD) is a relatively new entity in the family of cicatricial alopecia. It has been categorized as a member of the lichen planopilaris (LPP) group due to its similarity in clinical and histopathological presentation. Nonetheless, the disease earns its own entity due to its lichenoid inflammation exclusively involving miniaturized hair and area of involvement mimicking pattern hair loss which differentiates itself from other types of LPP or pattern hair loss. Since its first introduction by Zinkernagel and Trüeb in 2000, there have been only few case reports and series of FAPD. We herein report a case of FAPD in a postmenopausal woman who had progressive hair loss over the course of 10 years.

scholarly journals Incidental Syringomas of the Scalp in a Patient with Scarring Alopecia

2015 ◽  
Vol 7 (2) ◽  
pp. 171-177 ◽  
Author(s):  
Kristyn Deen ◽  
Claudia Curchin ◽  
Jason Wu
Keyword(s):  
Hair Loss ◽  
Unusual Case ◽  
Middle Aged ◽  
Cutaneous Lesions ◽  
Lichen Planopilaris ◽  
Scarring Alopecia ◽  
Periorbital Region ◽  
Neoplastic Lesions ◽  
Associated Conditions ◽  
Scalp Biopsy

Syringomas are benign adnexal neoplasms of eccrine lineage, which occur most commonly in the periorbital region in middle-aged females. These cutaneous lesions rarely occur on the scalp, are typically asymptomatic and are predominantly of cosmetic significance. Involvement of the scalp may be indistinguishable from that of scarring alopecia. We present an unusual case of clinically inapparent syringomas occurring on the scalp of a 56-year-old female with alopecia who was subsequently diagnosed with lichen planopilaris after repeated scalp biopsy. In patients with unexplained hair loss, or in cases that are refractive to treatment, clinicians should perform scalp biopsy to exclude the diagnosis of rare neoplastic lesions like syringomas and to diagnose associated conditions.

scholarly journals 451 Spironolactone for treatment of concomitant female pattern hair loss in scarring alopecia patients

2021 ◽  
Vol 141 (5) ◽  
pp. S78
Author(s):  
K.E. Flanagan ◽  
J.T. Pathoulas ◽  
C.J. Walker ◽  
I. M. Pupo Wiss ◽  
M.M. Senna
Keyword(s):  
Hair Loss ◽  
Scarring Alopecia ◽  
Female Pattern Hair Loss

Anagen Effluvium after Therapeutic Scalp Surgery: Unreported Phenomenon

2021 ◽  
Vol 7 (4) ◽  
pp. 311-314
Author(s):  
Leticia Arsie Contin ◽  
Leopoldo Duailibe Nogueira Santos ◽  
Ivan José Netto Pereira ◽  
Vanessa Barreto Rocha
Keyword(s):  
Hair Loss ◽  
Spontaneous Recovery ◽  
Case Reports ◽  
Practical Importance ◽  
Transient Ischemia ◽  
Melanocytic Nevi ◽  
Scarring Alopecia ◽  
Anagen Hair ◽  
Time Required

<b><i>Introduction:</i></b> Many procedures are performed on the scalp, such as excision of pilar and sebaceous cysts, melanocytic nevi, and reduction surgery for scarring alopecia, among others. In hair transplants, telogen effluvium is often reported 3 months after surgery; however, hair loss usually happens much earlier, around second week after the procedure, not compatible with the time required for hair to enter telogen and exogenous phases in normal conditions. <b><i>Case Reports:</i></b> We report 3 cases of anagen hair loss 4 weeks after surgeries, with perilesional trichoscopy suggesting anagen effluvium, with typical signs such as black dots and exclamation hairs. <b><i>Discussion:</i></b> There are only a few reports about hair loss around operated areas. The cause of this postoperative anagen effluvium is probably a transient ischemia. <b><i>Conclusion:</i></b> The practical importance of this phenomenon is to properly orient patients because most of the hair will be lost, since 85% of them are anagens, and also will have spontaneous recovery in the next 3 months.

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