scholarly journals Late Metastases from a Thin Primary Cutaneous Malignant Melanoma

2020 ◽  
Vol 78 (1) ◽  
pp. 71-74
Author(s):  
Regina Caldas ◽  
Filipa T. Almeida ◽  
Teresa Pereira ◽  
Inês Carvalho ◽  
Sofia D. Carvalho ◽  
...  
Keyword(s):  
Malignant Melanoma ◽  
Good Prognosis ◽  
Cutaneous Malignant Melanoma ◽  
Common Type ◽  
Tumor Thickness ◽  
Primary Cutaneous Malignant Melanoma ◽  
Great Ability ◽  
The Third ◽  
History Of

Cutaneous malignant melanoma is the third most common type of skin cancer, and its incidence has been rising. Its mortality rate is considerable, due to an aggressive phenotype and great ability of dissemination, mainly in the first years of follow- -up. Late recurrences, those presenting more than 10 years after diagnosis, are rare. The main prognostic factor of cutaneous malignant melanoma is tumor thickness, which also guides management. Thin tumors often have a good prognosis. We report a case of a 66-year-old woman with a history of excision of a thin primary cutaneous malignant melanoma of the dorsum, presenting 16 years later with an unexpected, rapidly progressing and lethal recurrence.

Breslow Thickness of Cutaneous Malignant Melanoma in Ravenna (Northern Italy) 1981–1990

1992 ◽  
Vol 78 (2) ◽  
pp. 94-97 ◽  
Author(s):  
Lauro Bucchi ◽  
Monica Serafini ◽  
Giuseppe Lanzanova
Keyword(s):  
Malignant Melanoma ◽  
Northern Italy ◽  
Cutaneous Malignant Melanoma ◽  
Tumor Thickness ◽  
Age Group ◽  
Primary Cutaneous Malignant Melanoma ◽  
Younger Women ◽  
Wilcoxon Rank Sum Test ◽  
The Difference ◽  
Low Incidence

The distribution of Breslow's thickness by sex, age and site of 95 of the 103 cases of primary cutaneous malignant melanoma (CMM) diagnosed in 1981–1990 in the Ravenna Health District (a low-incidence area in northern Italy) was studied. The median patient age was 57 years. The median tumor thickness was 1.33 mm in females and 2.15 mm in males (two-tailed Wilcoxon rank sum test, p = 0.153). Significantly thinner lesions were found among women up to the median age than among men of the same age group (1.05 mm vs. 1.80 mm, p = 0.034) and older women (2.20 mm, p = 0.035). The difference between males aged under 57 years and older than 57 was not significant (1.80 mm vs. 2.20 mm, p = 0.828). As a consequence, younger women compared favorably with the rest of the population as a whole (2.20 mm, p = 0.011). No significant differences in site-specific median tumor thickness were found between the sexes or between young and older males, whereas CMMs of the legs among females were thinner in the younger age group (0.67 mm vs. 2.20 mm, p = 0.007). The prevalence of younger women in the recognition of early CMM was entirely accounted for by a substantial shift observed in the most recent 5-year period (from 2.40 mm to 0.70 mm, p = 0.006). Specific educational activities have never been carried out in Ravenna.

The value of staging and serial follow-up investigations in patients with completely resected, primary, cutaneous malignant melanoma

1985 ◽  
Vol 72 (8) ◽  
pp. 614-617 ◽  
Author(s):  
Patricia A. Kersey ◽  
N. A. Iscoe ◽  
J. A. P. Gapski ◽  
D. Osoba ◽  
L. From ◽  
...  
Keyword(s):  
Malignant Melanoma ◽  
Cutaneous Malignant Melanoma ◽  
Primary Cutaneous Malignant Melanoma

Low-Grade Mucosa-Associated Lymphoid Tissue Lymphoma Involving the Kidney: Report of 3 Cases and Review of the Literature

2006 ◽  
Vol 130 (1) ◽  
pp. 86-89 ◽  
Author(s):  
Libo Qiu ◽  
Pamela D. Unger ◽  
Robert W. Dillon ◽  
James A. Strauchen
Keyword(s):  
Lymphoid Tissue ◽  
Cell Lymphoma ◽  
B Cell Lymphoma ◽  
Lymphoid Cells ◽  
Low Grade ◽  
The Third ◽  
First Case ◽  
Abundant Cytoplasm ◽  
History Of

Abstract Low-grade B-cell lymphoma of mucosa-associated lymphoid tissue involving the kidney is rare. We report a series of 3 cases. The first case occurred in an 83-year-old woman who presented with back pain. The second case was a 53-year-old man with a history of sarcoidosis who was found, in the course of evaluation of sarcoidosis, to have a right renal mass. The third case occurred in a 72-year-old man who had a history of periorbital mucosa–associated lymphoid tissue lymphoma and had been treated with surgery and radiation 1 year prior to this presentation. Histologically, all 3 patients showed infiltrate of uniform small-to-medium–sized lymphocytes with irregular nuclear contours and abundant cytoplasm resembling centrocytes or monocytoid lymphoid cells. The first patient received chemotherapy without complications. The second patient underwent a partial nephrectomy and was asymptomatic at the subsequent follow-up. The third patient developed a pulmonary embolism following nephrectomy, and further follow-up is not available.

Frequency, Predictors, and Outcome of Seizures in Patients With Myelomeningocele: Single-Center Retrospective Cohort Study

2021 ◽  
pp. 088307382110531
Author(s):  
Cemal Karakas ◽  
Emin Fidan ◽  
Kapil Arya ◽  
Troy Webber ◽  
Joan B. Cracco
Keyword(s):  
Good Prognosis ◽  
Cortical Atrophy ◽  
Seizure Freedom ◽  
Single Center ◽  
Seizure Onset ◽  
Shunt Procedure ◽  
History Of ◽  
The Mean

To determine the frequency, predictors, and outcomes of seizures in patients with myelomeningocele, we retrospectively analyzed the data from patients with myelomeningocele followed longitudinally at a single center from 1975 to 2013. We identified a total of 122 patients (61% female). The mean follow-up duration was 11.1 years (minimum-maximum = 0-34.5 years, SD = 8.8, median = 9.1 years). A total of 108 (88.5%) patients had hydrocephalus, and 98 (90.7%) of those patients required a ventriculoperitoneal shunt procedure. Twenty-four (19.7%) patients manifested with seizures, 23 of whom had hydrocephalus. The average age of seizure onset was 4.8 years (median 2 years of age). Falx dysgenesis ( P = .004), lumbar myelomeningocele ( P = .007), and cortical atrophy ( P = .028) were significantly associated with epileptic seizure development. The average seizure-free period at the last follow-up in patients with a history of myelomeningocele and seizures was 8.1 years. We conclude that myelomeningocele patients with seizures have an overall good prognosis with considerable long-term seizure freedom.

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