scholarly journals An IV Anesthetic Decision Tree for Cardiac Surgery

2020 ◽  
Author(s):  
Brian Doucette
Keyword(s):  
Systematic Review ◽  
Cardiac Surgery ◽  
Decision Tree ◽  
Structural Heart Disease ◽  
Controlled Trials ◽  
Intravenous Anesthetics ◽  
Intravenous Anesthetic ◽  
Randomized Controlled ◽  
Processing Theory ◽  
Selection Of

A thorough literature review was conducted covering the topics Intravenous anesthetics, pathophysiology of structural heart disease, and decision-making in anesthesia. A systematic review of randomized controlled trials was performed guided by the PRISMA protocol. Through the lens of Information Processing Theory, the results of the systematic review were used to guide the creation of a decision tree for the selection of the appropriate intravenous anesthetic for cardiac surgery.

scholarly journals Cardioplegia in paediatric cardiac surgery: a systematic review of randomized controlled trials

2018 ◽  
Vol 28 (1) ◽  
pp. 144-150 ◽  
Author(s):  
Nigel E Drury ◽  
Ivan Yim ◽  
Akshay J Patel ◽  
Nicola K Oswald ◽  
Cher-Rin Chong ◽  
...  
Keyword(s):  
Systematic Review ◽  
Cardiac Surgery ◽  
Randomized Controlled Trials ◽  
Controlled Trials ◽  
Randomized Controlled ◽  
Paediatric Cardiac Surgery

scholarly journals Do continuous forms of intra-operative ultrafiltration enhance recovery after adult cardiac surgery with cardiopulmonary bypass? A protocol for systematic review and meta-analysis of randomized controlled trials

2021 ◽  
Vol 10 (1) ◽  
Author(s):  
Joel Bierer ◽  
David Horne ◽  
Roger Stanzel ◽  
Mark Henderson ◽  
Leah Boulos ◽  
...  
Keyword(s):  
Systematic Review ◽  
Cardiac Surgery ◽  
Cardiopulmonary Bypass ◽  
High Risk ◽  
Meta Analysis ◽  
Risk Of Bias ◽  
Controlled Trials ◽  
Randomized Controlled ◽  
Inflammatory Syndrome ◽  
Adult Cardiac Surgery

Abstract Background Cardiac surgery with cardiopulmonary bypass (CPB) is associated with a systemic inflammatory syndrome that adversely impacts cardiopulmonary function and can contribute to prolonged postoperative recovery. Intra-operative ultrafiltration during CPB is a strategy developed by pediatric cardiac specialists, aiming to dampen the inflammatory syndrome by removing circulating cytokines and improving coagulation profiles during the cardiac operation. Although ultrafiltration is commonly used in the pediatric population, it is not routinely used in the adult population. This study aims to evaluate if randomized evidence supports the use of continuous intra-operative ultrafiltration to enhance recovery for adults undergoing cardiac surgery with CPB. Methods This systematic review and meta-analysis will include randomized controlled trials (RCT) that feature continuous forms of ultrafiltration during adult cardiac surgery with CPB, specifically assessing for benefit in mortality rates, invasive ventilation time and intensive care unit length of stay (ICU LOS). Relevant RCTs will be retrieved from databases, including MEDLINE, Embase, CENTRAL and Scopus, by a pre-defined search strategy. Search results will be screened for inclusion and exclusion criteria by two independent persons with consensus. Selected RCTs will have study demographics and outcome data extracted by two independent persons and transferred into RevMan. Risk of bias will be independently assessed by the Revised Cochrane Risk-of-Bias (RoB2) tool and studies rated as low-, some-, or high- risk of bias. Meta-analyses will compare the intervention of continuous ultrafiltration against comparators in terms of mortality, ventilation time, ICU LOS, and renal failure. Heterogeneity will be measured by the χ2 test and described by the I2 statistic. A sensitivity analysis will be completed by excluding included studies judged to have a high risk of bias. Summary of findings and certainty of the evidence, determined by the GRADE approach, will display the analysis findings. Discussion The findings of this systematic review and meta-analysis will summarize the evidence to date of continuous forms of ultrafiltration in adult cardiac surgery with CPB, to both inform adult cardiac specialists about this technique and identify critical questions for future research in this subject area. Systematic review registration This systematic review and meta-analysis is registered in PROSPERO CRD42020219309 (https://www.crd.york.ac.uk/prospero/display_record.php?ID=CRD42020219309). 

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