scholarly journals Development of a spheroid-permeable polymer

2021 ◽  
Vol 36 (4) ◽  
pp. 248-255
Author(s):  
Masaya Yamamoto ◽  
Nobuyuki Morimoto
Keyword(s):  
Permeable Polymer

scholarly journals Confinement of Therapeutic Enzymes in Selectively Permeable Polymer Vesicles by Polymerization-Induced Self-Assembly (PISA) Reduces Antibody Binding and Proteolytic Susceptibility

2018 ◽  
Vol 4 (6) ◽  
pp. 718-723 ◽  
Author(s):  
Lewis D. Blackman ◽  
Spyridon Varlas ◽  
Maria C. Arno ◽  
Zachary H. Houston ◽  
Nicholas L. Fletcher ◽  
...  
Keyword(s):  
Self Assembly ◽  
Antibody Binding ◽  
Polymer Vesicles ◽  
Permeable Polymer ◽  
Therapeutic Enzymes

scholarly journals Specific detection of biomolecules in physiological solutions using graphene transistor biosensors

2016 ◽  
Vol 113 (51) ◽  
pp. 14633-14638 ◽  
Author(s):  
Ning Gao ◽  
Teng Gao ◽  
Xiao Yang ◽  
Xiaochuan Dai ◽  
Wei Zhou ◽  
...  
Keyword(s):  
Ionic Strength ◽  
Real Time ◽  
Protein Detection ◽  
High Ionic Strength ◽  
Polymer Layer ◽  
General Strategy ◽  
Detection Of Biomolecules ◽  
Permeable Polymer ◽  
Graphene Devices ◽  
Modified Graphene

Nanomaterial-based field-effect transistor (FET) sensors are capable of label-free real-time chemical and biological detection with high sensitivity and spatial resolution, although direct measurements in high–ionic-strength physiological solutions remain challenging due to the Debye screening effect. Recently, we demonstrated a general strategy to overcome this challenge by incorporating a biomolecule-permeable polymer layer on the surface of silicon nanowire FET sensors. The permeable polymer layer can increase the effective screening length immediately adjacent to the device surface and thereby enable real-time detection of biomolecules in high–ionic-strength solutions. Here, we describe studies demonstrating both the generality of this concept and application to specific protein detection using graphene FET sensors. Concentration-dependent measurements made with polyethylene glycol (PEG)-modified graphene devices exhibited real-time reversible detection of prostate specific antigen (PSA) from 1 to 1,000 nM in 100 mM phosphate buffer. In addition, comodification of graphene devices with PEG and DNA aptamers yielded specific irreversible binding and detection of PSA in pH 7.4 1x PBS solutions, whereas control experiments with proteins that do not bind to the aptamer showed smaller reversible signals. In addition, the active aptamer receptor of the modified graphene devices could be regenerated to yield multiuse selective PSA sensing under physiological conditions. The current work presents an important concept toward the application of nanomaterial-based FET sensors for biochemical sensing in physiological environments and thus could lead to powerful tools for basic research and healthcare.

scholarly journals Strength and Solidification Mechanism of Silt Solidified by Polyurethane

2020 ◽  
Vol 2020 ◽  
pp. 1-9
Author(s):  
Fengyuan Li ◽  
Chaojie Wang ◽  
Yangyang Xia ◽  
Yanjie Hao ◽  
Peng Zhao ◽  
...  
Keyword(s):  
Unconfined Compressive Strength ◽  
Immersion Time ◽  
Mercury Intrusion Porosimetry ◽  
Polymer Content ◽  
X Ray Diffraction ◽  
X Ray ◽  
Mercury Intrusion ◽  
Grouting Material ◽  
Permeable Polymer ◽  
Solidification Mechanism

To determine the mechanism and strength characteristics of solidification of silt by a permeable polyurethane grouting material, the effects of polymer content, soil moisture, and immersion time on the unconfined compressive strength (UCS) of the silt have been studied. The results showed that the permeable polymer grouting material can significantly improve the performance of silt: (1) A higher amount of polymer produced a greater strength in the solidified soil. (2) The strength of the solidified soil increased as the immersion time was increased. (3) Moisture in the soil was not conducive to improving the strength of the solidified soil. The X-ray diffraction (XRD) and energy-dispersive spectroscopy (EDS) have proven that polyurethane does not react with the silt, but they could improve the strength of the silt through physical action. Mercury intrusion porosimetry (MIP) and scanning electron microscopy (SEM) were performed to find that polymers can reduce soil porosity, and the addition of polyurethane improved the strength of the silt mainly through adhesion, wrapping, filling, and bridging.

scholarly journals Drying of channels by evaporation through a permeable medium

2019 ◽  
Vol 16 (151) ◽  
pp. 20180690 ◽  
Author(s):  
Benjamin Dollet ◽  
Jean-François Louf ◽  
Mathieu Alonzo ◽  
Kaare H. Jensen ◽  
Philippe Marmottant
Keyword(s):  
Analytical Model ◽  
Excellent Agreement ◽  
Water Diffusion ◽  
Geometrical Parameters ◽  
Pdms Layer ◽  
Plant Leaves ◽  
Drying Process ◽  
Rock Disintegration ◽  
Permeable Polymer

We study the drying of isolated channels initially filled with water moulded in a water-permeable polymer (polydimethylsiloxane, PDMS) by pervaporation, when placed in a dry atmosphere. Channel drying is monitored by tracking a meniscus, separating water from air, advancing within the channels. The role of two geometrical parameters, the channel width and the PDMS thickness, is investigated experimentally. All data show that drying displays a truncated exponential dynamics. A fully predictive analytical model, in excellent agreement with the data, is proposed to explain such a dynamics, by solving water diffusion both in the PDMS layer and in the gas inside the channel. This drying process is crucial in geological or biological systems, such as rock disintegration or the drying of plant leaves after cavitation and embolism formation.

Triggered Enzymatic Degradation of DNA within Selectively Permeable Polymer Capsule Microreactors

2009 ◽  
Vol 48 (2) ◽  
pp. 329-332 ◽  
Author(s):  
Andrew D. Price ◽  
Alexander N. Zelikin ◽  
Yajun Wang ◽  
Frank Caruso
Keyword(s):  
Enzymatic Degradation ◽  
Permeable Polymer

Highly Permeable Polymer Membranes Containing Directed Channels for Water Purification

2012 ◽  
Vol 1 (6) ◽  
pp. 723-726 ◽  
Author(s):  
Hongyang Ma ◽  
Christian Burger ◽  
Benjamin S. Hsiao ◽  
Benjamin Chu
Keyword(s):  
Water Purification ◽  
Polymer Membranes ◽  
Permeable Polymer
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