Morphogenetic aspects of deer antler development

10.2741/e505 ◽  
2012 ◽  
Vol E4 (5) ◽  
pp. 1836-1842 ◽  
Author(s):  
Chunyi Li
Keyword(s):  
Deer Antler ◽  
Antler Development

scholarly journals Comparative proteomics analysis reveals the difference during antler regeneration stage between red deer and sika deer

PeerJ ◽  
2019 ◽  
Vol 7 ◽  
pp. e7299 ◽  
Author(s):  
Hang Su ◽  
Xiaolei Tang ◽  
Xiaocui Zhang ◽  
Li Liu ◽  
Li Jing ◽  
...  
Keyword(s):  
Red Deer ◽  
Sika Deer ◽  
Differentially Expressed ◽  
Differentially Expressed Proteins ◽  
Deer Antler ◽  
Biological Difference ◽  
Regeneration Stage ◽  
The Difference ◽  
Antler Tip ◽  
Antler Development

Deer antler, as the only mammalian regenerative appendage, provides an optimal model to study regenerative medicine. Antler harvested from red deer or sika deer were mainly study objects used to disclose the mechanism underlying antler regeneration over past decades. A previous study used proteomic technology to reveal the signaling pathways of antler stem cell derived from red deer. Moreover, transcriptome of antler tip from sika deer provide us with the essential genes, which regulated antler development and regeneration. However, antler comparison between red deer and sika deer has not been well studied. In our current study, proteomics were employed to analyze the biological difference of antler regeneration between sika deer and red deer. The proteomics profile was completed by searching the UniProt database, and differentially expressed proteins were identified by bioinformatic software. Thirty-six proteins were highly expressed in red deer antler, while 144 proteins were abundant in sika deer. GO and KEGG analysis revealed that differentially expressed proteins participated in the regulation of several pathways including oxidative phosphorylation, ribosome, extracellular matrix interaction, and PI3K-Akt pathway.

Histogenetic aspects of deer antler development

10.2741/e629 ◽  
2013 ◽  
Vol E5 (2) ◽  
pp. 479-489 ◽  
Author(s):  
Chunyi Li 
Keyword(s):  
Deer Antler ◽  
Antler Development

Iodine Distribution in the Environment as a Limiting Factor for Roe Deer Antler Development

2010 ◽  
Vol 139 (2) ◽  
pp. 168-176 ◽  
Author(s):  
Róbert Lehoczki ◽  
Károly Erdélyi ◽  
Krisztina Sonkoly ◽  
László Szemethy ◽  
Sándor Csányi
Keyword(s):  
Roe Deer ◽  
Limiting Factor ◽  
Deer Antler ◽  
Antler Development

Effect of Metabolic Acidosis on White‐Tailed Deer Antler Development

2000 ◽  
Vol 73 (6) ◽  
pp. 781-789 ◽  
Author(s):  
Tyler A. Campbell ◽  
David G. Hewitt
Keyword(s):  
Metabolic Acidosis ◽  
Deer Antler ◽  
Antler Development

Pemanfaatan Tanduk Rusa Baldu Untuk Tujuan Perubatan Menurut Perspektif Halal dan Haram

Sains Insani ◽  
2018 ◽  
Vol 3 (2) ◽  
pp. 60-67
Author(s):  
Mohd Mahyeddin Mohd Salleh ◽  
Irwan Mohd Subri
Keyword(s):  
Traditional Medicine ◽  
Animal Suffering ◽  
Deer Antler ◽  
Scientific Observation ◽  
Animal Organ ◽  
Asean Countries

Deer antler velvet is one of the important ingredients used in traditional medicine by many Asean countries including Malaysia. However, there is doubt regarding the halalness of the medicine derived from deer antler velvet taken alive due to the conflict of fatwa. The objective of this paper is to analyse the position of medicine derives from deer antler velvet from Shariah perspectives. The qualitative methode used through documents analysis, interview and observation. The finding shows that the conflict exists because of the different of ijtihad when the deer antler velvet taken from the animal alive. It is due to the issue, whether it hurt the animal or vice versa. Based on the scientific observation, it is proven that deer antler velvet is part of the animal organ and the nerve connected can make the animal suffering if it is taken alive. It is totally different from halal animal fur that remove while they still alive. Thus, any medication derived from deer antler velvet is not permissible and unclean (najs). Alternatively, to make it halal, the animal should be slaughtered before removing the deer antler valvet.   Keywords: deer antler velvet, medicine, fatwa, halal, haram   ABSTRAK: Tanduk rusa baldu merupakan antara bahan penting yang dimanfaatkan dalam bidang perubatan herba tradisional di kebanyakan negara asia, termasuk di Malaysia. Bagaimanapun, timbul ketidakpastian hukum terhadap ubat tanduk rusa baldu yang dipotong ketika masih hidup, iaitu sama ada ia boleh dikategorikan sebagai produk yang halal atau haram untuk dimanfaatkan, lantaran wujud konflik fatwa di Malaysia mengenainya. Objektif kajian ini adalah bagi menganalisis hukum ubat daripada tanduk rusa baldu menurut perpektif halal dan haram. Bagi mencapai objektif tersebut, kaedah kualitatif digunakan menerusi pendekatan analisis dokumen, temubual dan pemerhatian. Hasil kajian mendapati antara punca perbezaan pendapat fuqaha dalam menentukan hukum tanduk yang dipotong semasa hidup adalah disebabkan ijtihad mereka yang berbeza terhadap tanduk haiwan, iaitu sama ada ia termasuk dalam kategori anggota yang menyakitkan jika dipotong atau tidak menyakitkan. Berdasarkan maklumat saintifik dan pemerhatian, terbukti bahawa tanduk rusa baldu adalah sejenis anggota yang bersaraf dan menyakitkan jika dipotong ketika hidup, dan tidak boleh disamakan dengan kes bulu haiwan halal. Justeru, produk perubatan berasaskan tanduk rusa yang diperolehi secara kaedah pemotongan tersebut adalah haram dan najis. Sebagai alternatif, pengambilan tanduk rusa menerusi kaedah penyembelihan secara syarak boleh menukar statusnya menjadi produk yang halal.   Kata kunci: tanduk rusa, baldu, perubatan, fatwa, halal, haram

Effects of the Deer Antler Extract on Scopolamine-induced Memory Impairment and Its Related Enzyme Activities

2009 ◽  
Vol 38 (4) ◽  
pp. 409-414 ◽  
Author(s):  
Mi-Ra Lee ◽  
Bai-Shen Sun ◽  
Li-Juan Gu ◽  
Chun-Yan Wang ◽  
Zhe-Ming Fang ◽  
...  
Keyword(s):  
Enzyme Activities ◽  
Memory Impairment ◽  
Deer Antler ◽  
Related Enzyme

Changes in Properties of Deer Antler by Proteolysis and Extraction Conditions

2011 ◽  
Vol 40 (1) ◽  
pp. 89-93 ◽  
Author(s):  
Jae-Hwa Kim ◽  
Cheol-Jae Yoo ◽  
Kyung-A Sin ◽  
Se-Young Jang ◽  
Nan-Young Park ◽  
...  
Keyword(s):  
Deer Antler

The effect of deer antler from East Kalimantan to increase trabecular bone density and calcium levels in serum on osteoporotic mice

2021 ◽  
Vol 0 (0) ◽  
Author(s):  
Retno Widyowati ◽  
Suciati Suciati ◽  
Dewi Melani Haryadi ◽  
Hsin-I Chang ◽  
IPG Ngurah Suryawan ◽  
...  
Keyword(s):  
Bone Density ◽  
Trabecular Bone ◽  
Aqueous Extract ◽  
Dependent Manner ◽  
Aqueous Extracts ◽  
Trabecular Bone Density ◽  
Male Mice ◽  
Deer Antler ◽  
East Kalimantan ◽  
Dose Dependent

Abstract Objectives Glucocorticoid-induced osteoporosis (dexamethasone) is a primary cause of secondary osteoporosis by the decreasing formation and increasing resorption activities. Previously, the in vitro study showed that 70% ethanol and aqueous extract of deer antler have increased alkaline phosphatase in osteoblast cell that known as marker of bone formation. The mind of this study is to analyze the effect of deer antlers in increasing the bone trabecular density of osteoporosis-induced male mice. Methods This study used a post-test control group design. A total of 54 healthy male mice were randomly divided to nine groups, i.e., healthy control, osteoporotic, positive control, 70% ethanol (4, 8, and 12 mg/kg BW), and aqueous extracts (4, 8, and 12 mg/kg BW) of deer antler groups. All of the interventions were given 1 mL of test sample for 4 weeks orally. The bone densities were determined using histomorphometry by Image J and Adobe Photoshop. The statistical data were performed using SPSS 23 and statistical significance was set at p<0.05. Results The results showed that alendronate group, 70% ethanol, and aqueous extract groups increased bone density and calcium levels in serum (p<0.05) compared to osteoporotic group in dose dependent manner. It indicated that 70% ethanol and aqueous extract of deer antler stimulating bone turnover and aqueous extract showed the highest. Conclusions Dexamethasone induction for 4 weeks caused osteoporotic mice and the administration of 70% ethanol and aqueous extracts of deer antler from East Kalimantan increased trabecular bone density and calcium levels in dose dependent manner.

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